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At-rest lateral earth pressure of compacted expansive soils:Experimental investigations and prediction approach
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作者 Zhong Han pan zhang +3 位作者 Weilie Zou Kewei Fan Sai K.Vanapalli Lianglong Wan 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第4期1425-1435,共11页
This paper presents experimental studies on a compacted expansive soil,from Nanyang,China for investigating the at-rest lateral earth pressureσL of expansive soils.The key studies include(i)relationships between the... This paper presents experimental studies on a compacted expansive soil,from Nanyang,China for investigating the at-rest lateral earth pressureσL of expansive soils.The key studies include(i)relationships between theσL and the vertical stressσV during soaking and consolidation,(ii)the influences of initial dry densityρd0 and moisture content w 0 on the vertical and lateral swelling pressures at no swelling strain(i.e.σV0 andσL0),and(iii)evolution of theσL during five long-term wetting-drying cycles.Experimental results demonstrated that the post-soakingσL-σV relationships are piecewise linear and their slopes in the passive state(σL>σV)and active state(σL<σV)are similar to that of the consolidationσL-σV relationships in the normal-and over-consolidated states,respectively.The soakingσL-σV relationships converge to the consolidationσL-σV relationships at a thresholdσV where the interparticle swelling is restrained.TheσL0 andσV0 increase monotonically withρd0;however,they show increasing-then-decreasing trends with the w 0.The extent of compaction-induced swelling anisotropy,which is evaluated byσL0/σV0,reduces with an increase in the compaction energy and molding water content.TheσL reduces over moisture cycles and the stress relaxation in theσL during soaking is observed.An approach was developed to predict the at-rest soakingσL-σV relationships,which requires conventional consolidation and shear strength properties and one measurement of theσL-σV relationships during soaking.The proposed approach was validated using the results of three different expansive soils available in the literature. 展开更多
关键词 Lateral earth pressure Expansive soil SOAKING Vertical stress Swelling pressure
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Mass transfer enhancement and hydrodynamic performance with wire mesh coupling solid particles in bubble column reactor
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作者 Chuanjun Di Jipeng Dong +3 位作者 Fei Gao Guanghui Chen pan zhang Jianlong Li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第3期195-205,共11页
It is of vital significance to investigate mass transfer enhancements for chemical engineering processes.This work focuses on investigating the coupling influence of embedding wire mesh and adding solid particles on b... It is of vital significance to investigate mass transfer enhancements for chemical engineering processes.This work focuses on investigating the coupling influence of embedding wire mesh and adding solid particles on bubble motion and gas-liquid mass transfer process in a bubble column.Particle image velocimetry(PIV)technology was employed to analyze the flow field and bubble motion behavior,and dynamic oxygen absorption technology was used to measure the gas-liquid volumetric mass transfer coefficient(kLa).The effect of embedding wire mesh,adding solid particles,and wire mesh coupling solid particles on the flow characteristic and kLa were analyzed and compared.The results show that the gas-liquid interface area increases by 33%-72%when using the wire mesh coupling solid particles strategy compared to the gas-liquid two-phase flow,which is superior to the other two strengthening methods.Compared with the system without reinforcement,kLa in the bubble column increased by 0.5-1.8 times with wire mesh coupling solid particles method,which is higher than the sum of kLa increases with inserting wire mesh and adding particles,and the coupling reinforcement mechanism for affecting gas-liquid mass transfer process was discussed to provide a new idea for enhancing gas-liquid mass transfer. 展开更多
关键词 Fluid mechanics BUBBLE Mass transfer Wire mesh coupling solid particles Particle image velocimetry Hydrodynamics
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新工科背景下“大学物理”课程考核方式改革实践
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作者 潘章 陈静 《唐山学院学报》 2024年第2期104-108,共5页
针对考核方式存在的问题,根据新工科对人才培养的新要求,提出了“大学物理”课程考核方式改革方案:增加考核次数、创新过程考核方法、增设综合能力考核,以此通过增强过程考核来加强对学生综合能力的培养。通过对考核方式进行效果评估和... 针对考核方式存在的问题,根据新工科对人才培养的新要求,提出了“大学物理”课程考核方式改革方案:增加考核次数、创新过程考核方法、增设综合能力考核,以此通过增强过程考核来加强对学生综合能力的培养。通过对考核方式进行效果评估和对比改革前后的教学效果可以看出,改革后的考核方式较好地提升了课程教学质量,并形成了良好的教学反馈机制。 展开更多
关键词 大学物理 考核方式 新工科
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Multi-source coordinated stochastic restoration for SOP in distribution networks with a two-stage algorithm 被引量:1
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作者 Xianxu Huo pan zhang +3 位作者 Tao zhang Shiting Sun Zhanyi Li Lei Dong 《Global Energy Interconnection》 EI CAS CSCD 2023年第2期141-153,共13页
After suffering from a grid blackout, distributed energy resources(DERs), such as local renewable energy and controllable distributed generators and energy storage can be used to restore loads enhancing the system’s ... After suffering from a grid blackout, distributed energy resources(DERs), such as local renewable energy and controllable distributed generators and energy storage can be used to restore loads enhancing the system’s resilience. In this study, a multi-source coordinated load restoration strategy was investigated for a distribution network with soft open points(SOPs). Here, the flexible regulation ability of the SOPs is fully utilized to improve the load restoration level while mitigating voltage deviations. Owing to the uncertainty, a scenario-based stochastic optimization approach was employed,and the load restoration problem was formulated as a mixed-integer nonlinear programming model. A computationally efficient solution algorithm was developed for the model using convex relaxation and linearization methods. The algorithm is organized into a two-stage structure, in which the energy storage system is dispatched in the first stage by solving a relaxed convex problem. In the second stage, an integer programming problem is calculated to acquire the outputs of both SOPs and power resources. A numerical test was conducted on both IEEE 33-bus and IEEE 123-bus systems to validate the effectiveness of the proposed strategy. 展开更多
关键词 Load restoration Soft open points Distribution network Stochastic optimization Two-stage algorithm
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Variational quantum simulation of thermal statistical states on a superconducting quantum processer
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作者 郭学仪 李尚书 +11 位作者 效骁 相忠诚 葛自勇 李贺康 宋鹏涛 彭益 王战 许凯 张潘 王磊 郑东宁 范桁 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第1期74-87,共14页
Quantum computers promise to solve finite-temperature properties of quantum many-body systems,which is generally challenging for classical computers due to high computational complexities.Here,we report experimental p... Quantum computers promise to solve finite-temperature properties of quantum many-body systems,which is generally challenging for classical computers due to high computational complexities.Here,we report experimental preparations of Gibbs states and excited states of Heisenberg X X and X X Z models by using a 5-qubit programmable superconducting processor.In the experiments,we apply a hybrid quantum–classical algorithm to generate finite temperature states with classical probability models and variational quantum circuits.We reveal that the Hamiltonians can be fully diagonalized with optimized quantum circuits,which enable us to prepare excited states at arbitrary energy density.We demonstrate that the approach has a self-verifying feature and can estimate fundamental thermal observables with a small statistical error.Based on numerical results,we further show that the time complexity of our approach scales polynomially in the number of qubits,revealing its potential in solving large-scale problems. 展开更多
关键词 superconducting qubit quantum simulation variational quantum algorithm quantum statistical mechanics machine learning
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Synergy mechanism of defect engineering in MoS_(2)/FeS_(2)/C heterostructure for high-performance sodium-ion battery
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作者 Linlin Ma Xiaomei Zhou +9 位作者 Jun Sun pan zhang Baoxiu Hou Shuaihua zhang Ningzhao Shang Jianjun Song Hongjun Ye Hui Shao Yongfu Tang Xiaoxian Zhao 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2023年第7期268-276,I0006,共10页
MoS_(2) is a promising anode material in sodium-ion battery technologies for possessing high theoretical capacity.However,the sluggish Na^(+) diffusion kinetics and low electronic conductivity hinder the promises.Here... MoS_(2) is a promising anode material in sodium-ion battery technologies for possessing high theoretical capacity.However,the sluggish Na^(+) diffusion kinetics and low electronic conductivity hinder the promises.Herein,a unique MoS_(2)/FeS_(2)/C heterojunction with abundant defects and hollow structure(MFCHHS)was constructed.The synergy of defect engineering in MoS_(2),FeS_(2),and the carbon layer of MFCHHS with a larger specific surface area provides multiple storage sites of Na^(+)corresponding to the surface-controlled process.The MoS_(2)/FeS_(2)/C heterostructure and rich defects in MoS_(2) and carbon layer lower the Na^(+) diffusion energy barrier.Additionally,the construction of MoS_(2)/FeS_(2) heterojunction promotes electron transfer at the interface,accompanying with excellent conductivity of the carbon layer to facilitate reversible electrochemical reactions.The abundant defects and mismatches at the interface of MoS_(2)/FeS_(2) and MoS_(2)/C heterojunctions could relieve lattice stress and volume change sequentially.As a result,the MFCHHS anode exhibits the high capacity of 613.1 mA h g^(-1)at 0.5 A g^(-1) and 306.1 mA h g^(-1) at 20 A g^(-1).The capacity retention of 85.0%after 1400 cycles at 5.0 A g^(-1) is achieved.The density functional theory(DFT)calculation and in situ transmission electron microscope(TEM),Raman,ex-situ X-ray photon spectroscopy(XPS)studies confirm the low volume change during intercalation/deintercalation process and the efficient Na^(+)storage in the layered structure of MoS_(2) and carbon layer,as well as the defects and heterostructures in MFCHHS.We believe this work could provide an inspiration for constructing heterojunction with abundant defects to foster fast electron and Na^(+) diffusion kinetics,resulting in excellent rate capability and cycling stability. 展开更多
关键词 Defect engineering HETEROSTRUCTURE Hollow structure Sodium-ion battery MoS_(2)/FeS_(2)
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Loss of behavioral stress response in blind cavefish reduces energy expenditure
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作者 Jiang-Hui zhang Rui Long +5 位作者 Yang-Yang Jing pan zhang Yuan Xu Wei Xiong Yan-Qiu Zhu Yi-Ping Luo 《Zoological Research》 SCIE CSCD 2023年第4期678-692,共15页
The stress response is essential for animal self-defense and survival. However, species may exhibit stress response variation depending on their specific environmental and selection pressures. Blind cavefish dwell in ... The stress response is essential for animal self-defense and survival. However, species may exhibit stress response variation depending on their specific environmental and selection pressures. Blind cavefish dwell in cave environments, which differ markedly in stressors and resource availability compared to surface aquatic environments. However, whether blind cavefish exhibit differences in stress response as an adaptation to their cave environments remains unclear. Here, we investigated differences in stress response in six closely related Triplophysa species, including three blind cavefish (T. longibarbata, T. jiarongensis, and T. rosa) and three normal-sighted river fish (T. nasobarbatula, T. dongsaiensis, and T. bleekeri). Results showed that blind cavefish exhibited a range of distinct behavioral responses compared to sighted river fish, including greater levels of activity, shorter duration of freezing, absence of erratic movements or thrashing behavior, and opposite behavioral trends over time. Furthermore, the cavefish species demonstrated attenuated increases in metabolic rate in response to stressors related to novel environments. Cave-dwelling T. rosa also exhibited lower basal hypothalamic-pituitary-inter-renal (HPI) axis-related gene expression levels and stress hormone concentrations compared to river-dwelling T. bleekeri. These results suggest that blind cavefish may have lost their behavioral stress response, potentially mediated by a reduction in basal activity of the HPI axis, thus enabling the conservation of energy by reducing unnecessary expenditure in energy-limited caves. 展开更多
关键词 CAVEFISH Stress responses BEHAVIOR Metabolic rate
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In-situ 3D contour measurement for laser powder bed fusion based on phase guidance
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作者 Yuze zhang pan zhang +3 位作者 Xin Jiang Siyuan zhang Kai Zhong Zhongwei Li 《Theoretical & Applied Mechanics Letters》 CAS CSCD 2023年第2期113-119,共7页
In-situ layerwise imaging measurement of laser powder bed fusion(LPBF)provides a wealth of forming and defect data which enables monitoring of components quality and powder bed homogeneity.Using high-resolution camera... In-situ layerwise imaging measurement of laser powder bed fusion(LPBF)provides a wealth of forming and defect data which enables monitoring of components quality and powder bed homogeneity.Using high-resolution camera layerwise imaging and image processing algorithms to monitor fusion area and powder bed geometric defects has been studied by many researchers,which successfully monitored the contours of components and evaluated their accuracy.However,research for the methods of in-situ 3D contour measurement or component edge warping identification is rare.In this study,a 3D contour mea-surement method combining gray intensity and phase difference is proposed,and its accuracy is verified by designed experiments.The results show that the high-precision of the 3D contours can be achieved by the constructed energy minimization function.This method can detect the deviations of common ge-ometric features as well as warpage at LPBF component edges,and provides fundamental data for in-situ quality monitoring tools. 展开更多
关键词 Laser powder bed fusion In-situ measurement Active contours 3D contour Measurement accuracy
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Preparation and Performance of n-Dodecane Microencapsulated Phase Change Cold Storage Materials
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作者 pan zhang Lingling Xu +2 位作者 Xin Shi Zemeng Guo Jiajia Cheng 《Journal of Renewable Materials》 SCIE EI 2023年第2期689-705,共17页
Cold chain transportation is currently a hot research topic.Since the traditional refrigeration methods lead to the consumption of large amounts of energy,the search for new energy storage materials is a major trend.I... Cold chain transportation is currently a hot research topic.Since the traditional refrigeration methods lead to the consumption of large amounts of energy,the search for new energy storage materials is a major trend.In the present contribution,n-dodecane/PMMA microencapsulated phase change materials were prepared by suspension polymerization for ice-temperature cold chain transportation and their preparation parameters were explored using the encapsulation ratio as optimization indicator.The results show that the n-dodecane-containing microcapsules have a maximum encapsulation ratio of 93.2%when using a core-to-wall ratio of 3:1,5%of emulsifier,30%of crosslinker,and 2000 rpm of emulsification speed.The phase transition temperature and enthalpy are-2℃and 195.9 kJ/kg,respectively.The microcapsules prepared with the optimized process parameters have good microscopic morphology,high energy storage efficiency,uniform particle size and good thermal stability,making them ideal materials for cold chain transportation. 展开更多
关键词 Phase change microcapsules N-DODECANE suspension polymerization cold storage
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RT-YOLO:A Residual Feature Fusion Triple Attention Network for Aerial Image Target Detection
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作者 pan zhang Hongwei Deng Zhong Chen 《Computers, Materials & Continua》 SCIE EI 2023年第4期1411-1430,共20页
In recent years,target detection of aerial images of unmannedaerial vehicle(UAV)has become one of the hottest topics.However,targetdetection of UAV aerial images often presents false detection and misseddetection.We p... In recent years,target detection of aerial images of unmannedaerial vehicle(UAV)has become one of the hottest topics.However,targetdetection of UAV aerial images often presents false detection and misseddetection.We proposed a modified you only look once(YOLO)model toimprove the problems arising in object detection in UAV aerial images:(1)A new residual structure is designed to improve the ability to extract featuresby enhancing the fusion of the inner features of the single layer.At the sametime,triplet attention module is added to strengthen the connection betweenspace and channel and better retain important feature information.(2)Thefeature information is enriched by improving the multi-scale feature pyramidstructure and strengthening the feature fusion at different scales.(3)A newloss function is created and the diagonal penalty term of the anchor frame isintroduced to improve the speed of training and the accuracy of reasoning.The proposed model is called residual feature fusion triple attention YOLO(RT-YOLO).Experiments showed that the mean average precision(mAP)ofRT-YOLO is increased from 57.2%to 60.8%on the vehicle detection in aerialimage(VEDAI)dataset,and the mAP is also increased by 1.7%on the remotesensing object detection(RSOD)dataset.The results show that theRT-YOLOoutperforms other mainstream models in UAV aerial image object detection. 展开更多
关键词 Attention mechanism small target detection YOLOv5s RT-YOLO
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Letter to editor‘Non-invasive model for predicting high-risk esophageal varices based on liver and spleen stiffness’
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作者 Xin Gao Xiao-Yan Guo +6 位作者 Long-Bao Yang Zhong-Cao Wei pan zhang Ya-Tao Wang Chen-Yu Liu Dan-Yang zhang Yan Wang 《World Journal of Hepatology》 2023年第11期1250-1252,共3页
predicting high-risk esophageal varices based on liver and spleen stiffness".Acute bleeding caused by esophageal varices is a life-threatening complication in patients with liver cirrhosis.Due to the discomfort,c... predicting high-risk esophageal varices based on liver and spleen stiffness".Acute bleeding caused by esophageal varices is a life-threatening complication in patients with liver cirrhosis.Due to the discomfort,contraindications,and associated complications of upper gastrointestinal endoscopy screening,it is crucial to identify an imaging-based non-invasive model for predicting high-risk esophageal varices in patients with cirrhosis. 展开更多
关键词 CIRRHOSIS High-risk esophageal varices Non-invasive prediction model Spleen stiffness measurement Liver stiffness measurement Upper gastrointestinal endoscopy
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毛细吸水作用对水泥砂浆电阻率的影响研究 被引量:4
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作者 曾晓辉 凌晨博 +4 位作者 潘璋 王平 李鲲鹏 罗信伟 崖尚松 《建筑材料学报》 EI CAS CSCD 北大核心 2018年第5期714-719,共6页
采用四电极法测定了水泥砂浆电阻率随毛细吸水时间的变化,并分析了水灰比、聚合物乳液、引气剂对其变化的影响.研究表明:随毛细吸水时间的增加,水泥砂浆电阻率先缓慢降低,随后迅速下降,最后保持稳定;毛细吸水可使水泥砂浆电阻率降低70%... 采用四电极法测定了水泥砂浆电阻率随毛细吸水时间的变化,并分析了水灰比、聚合物乳液、引气剂对其变化的影响.研究表明:随毛细吸水时间的增加,水泥砂浆电阻率先缓慢降低,随后迅速下降,最后保持稳定;毛细吸水可使水泥砂浆电阻率降低70%以上,这可能与吸水后砂浆内部形成的孔隙导电通道有关;增大水灰比和掺入引气剂均可大幅度提高干燥条件下砂浆的电阻率,且对吸水状态下砂浆的电阻率也有一定提高作用,但对吸水后砂浆的电阻率影响不大;6%聚合物乳液掺量(聚合物的固含量占水泥质量的百分数)不仅可提高干燥条件下的砂浆电阻率,也可提高吸水后的砂浆电阻率(提高4倍左右,且保持在360Ω·m以上),原因可能与水灰比、聚合物乳液、引气剂对砂浆毛细孔隙结构的影响有关. 展开更多
关键词 毛细吸水作用 水泥砂浆 电阻率 四电极法 孔隙结构
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在有机化学实验中设置计算化学模块 被引量:7
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作者 李田 张攀 +5 位作者 边磊 关玲 徐烜峰 张奇涵 王婕妤 王颖霞 《大学化学》 CAS 2021年第1期111-116,共6页
计算化学快速发展,对于化学研究有非常强的指导作用,因此将其引入本科低年级实验教学很有必要。本文在调研国内外高校计算化学课程开设情况的基础上,根据本院学生特点和课程的需要,在面向大一本科生的核心实验课程——有机化学实验中引... 计算化学快速发展,对于化学研究有非常强的指导作用,因此将其引入本科低年级实验教学很有必要。本文在调研国内外高校计算化学课程开设情况的基础上,根据本院学生特点和课程的需要,在面向大一本科生的核心实验课程——有机化学实验中引入了计算模块。模块设计从实验问题出发,将计算项目和实验紧密结合,采用分层次教学的模式进行。利用Canvas线上教学平台对微课、讲义、作业、测验等学习资源进行有效组织,通过直播课和微信群进行讨论和答疑,以翻转课堂的形式进行混合式教学,取得了很好的教学效果。 展开更多
关键词 计算化学 有机化学实验 Gaussian 03程序 翻转课堂 微课 Canvas教学平台
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促聚合与生物矿化改善轨道板用钠水玻璃性能 被引量:1
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作者 李茂红 潘璋 +3 位作者 凌晨博 姚宁 李书娴 王平 《西南交通大学学报》 EI CSCD 北大核心 2019年第4期879-884,共6页
为改善高铁轨道板涂料用钠水玻璃力学强度和耐水性,通过添加Ca(H2PO4)2,达到促进钠水玻璃生物矿化、提高硅氧聚合程度的目的.首先在钠水玻璃中添加Ca(H2PO4)2制作样品,以未添加Ca(H2PO4)2的样品作空白对照;然后用万能材料试验机、耐水... 为改善高铁轨道板涂料用钠水玻璃力学强度和耐水性,通过添加Ca(H2PO4)2,达到促进钠水玻璃生物矿化、提高硅氧聚合程度的目的.首先在钠水玻璃中添加Ca(H2PO4)2制作样品,以未添加Ca(H2PO4)2的样品作空白对照;然后用万能材料试验机、耐水性试验检测样品性能,并用X-射线衍射仪、傅里叶红外光谱仪、固体核磁共振仪测试其微观组成和结构.研究结果表明:Ca(H2PO4)2添加导致钠水玻璃力学强度提高160%,耐水性由浸水2 h完全溃散提高至浸水7 d无明显损坏;促使钠水玻璃仿生矿化形成力学强度高、耐水性好的人体骨主要无机成分Ca8H2(PO4)6?H2O-NaHCO3-H2O;增强钠水玻璃中硅氧的聚合,使之形成耐水性更好的硅氧聚合体.可推断得,添加Ca(H2PO4)2可明显提高钠水玻璃凝结硬化后力学强度和耐水性,具有应用于轨道板涂料的前景. 展开更多
关键词 聚合 生物矿化 钠水玻璃 耐水性 力学强度
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乳化沥青对水化硅酸钙孔结构及微观形貌的影响 被引量:3
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作者 曾晓辉 朱华胜 +2 位作者 潘璋 刘海川 凌晨博 《建筑材料学报》 EI CAS CSCD 北大核心 2019年第5期756-763,共8页
针对未掺乳化沥青的纯水化硅酸钙和用Na2SiO3·9H2O,Ca(NO3)2·4H2O,NaOH,去离子水及阴离子乳化沥青合成的水化硅酸钙,采用氮吸附-脱附试验、X射线衍射(XRD)和扫描电镜(SEM)等测试方法对比研究了乳化沥青对水化硅酸钙孔结构及... 针对未掺乳化沥青的纯水化硅酸钙和用Na2SiO3·9H2O,Ca(NO3)2·4H2O,NaOH,去离子水及阴离子乳化沥青合成的水化硅酸钙,采用氮吸附-脱附试验、X射线衍射(XRD)和扫描电镜(SEM)等测试方法对比研究了乳化沥青对水化硅酸钙孔结构及微观形貌的影响,并运用FHH模型分析了其表面分形特征.结果表明:纯水化硅酸钙和掺杂乳化沥青的水化硅酸钙比表面积相差较小,且微孔分布几乎一致,说明掺杂乳化沥青后插层作用和"开孔"效应并未发生;乳化沥青可促进水化硅酸钙形成孔径较大的中孔,减少孔径较小的中孔,而对大孔及微孔的孔结构几乎没有影响;纯水化硅酸钙和掺杂乳化沥青的水化硅酸钙表面分形特征存在差异;沥青表面乳化剂中的-COOM基团与Ca键合可使水化硅酸钙胶束包裹在乳化沥青颗粒表面. 展开更多
关键词 水化硅酸钙 乳化沥青 氮吸附 孔结构 分形特征
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事件要素注意力与编码层融合的触发词抽取研究 被引量:9
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作者 潘璋 黄德根 《小型微型计算机系统》 CSCD 北大核心 2021年第4期673-677,共5页
事件抽取是信息抽取的主要任务之一,而触发词抽取是事件抽取的重要子任务.事件要素与事件触发词之间存在关联信息,现有的事件触发词抽取方法主要关注事件触发词本身,没有充分的利用事件要素信息.因此,提出一种事件要素注意力与编码层融... 事件抽取是信息抽取的主要任务之一,而触发词抽取是事件抽取的重要子任务.事件要素与事件触发词之间存在关联信息,现有的事件触发词抽取方法主要关注事件触发词本身,没有充分的利用事件要素信息.因此,提出一种事件要素注意力与编码层融合的事件触发词抽取模型,能够有效地利用事件要素信息,提高触发词抽取性能.通过事件要素与事件触发词之间的相关性来显示利用事件要素信息,同时利用编码层的多头自注意力机制间接学习事件要素与事件触发词之间的依赖关系,并将两个方法得到的输出向量进行处理,作为特征送入到编码层中进行训练.此外,通过词特征模型获取语义信息.该方法在ACE2005英文语料上对事件触发词抽取的F值达到71.95%. 展开更多
关键词 事件触发词抽取 事件要素注意力 编码层 词特征
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结构可控串珠状异质纤维薄膜的制备及在药物释放领域的应用 被引量:5
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作者 张盼 潘凯 《高分子材料科学与工程》 EI CAS CSCD 北大核心 2018年第7期167-172,共6页
通过结合静电喷雾和静电纺丝的方法,运用低浓度的聚乳酸溶液进行静电喷雾制备珠粒,同时用高浓度的聚丙烯腈溶液进行静电纺丝制备纤维,在接收板上成功制得均匀可控的串珠状异质纤维。运用制备得到的串珠纤维加载地塞米松进行药物释放研究... 通过结合静电喷雾和静电纺丝的方法,运用低浓度的聚乳酸溶液进行静电喷雾制备珠粒,同时用高浓度的聚丙烯腈溶液进行静电纺丝制备纤维,在接收板上成功制得均匀可控的串珠状异质纤维。运用制备得到的串珠纤维加载地塞米松进行药物释放研究,在波长为241 nm处测量载药纤维薄膜在磷酸盐模拟体液中溶出液的吸光度,测得地塞米松随着时间的延长,溶出速度加快,到2 h左右时,药物释放量达60%左右,到6 h左右已基本全部溶出,具有良好的药物缓释效果。 展开更多
关键词 串珠状 异质纤维 静电喷雾 静电纺丝 药物释放
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象似性手势在儿童早期词汇学习中的作用 被引量:3
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作者 张攀 王娟 《学前教育研究》 CSSCI 北大核心 2021年第4期48-57,共10页
象似性手势是指在形式和表达方式上与其所伴随的言语的语义内容密切相关的手势。儿童通常在18~24个月产生象似性手势,到3岁时能准确理解象似性手势的含义。象似性手势的产生和理解与儿童年龄呈正相关,且受文化等社会因素的影响较大。象... 象似性手势是指在形式和表达方式上与其所伴随的言语的语义内容密切相关的手势。儿童通常在18~24个月产生象似性手势,到3岁时能准确理解象似性手势的含义。象似性手势的产生和理解与儿童年龄呈正相关,且受文化等社会因素的影响较大。象似性手势能够揭示儿童的象征发展水平,解释并再现言语组织过程,补充言语中未表达的信息,促进多通道表征,提高词汇加工效率,因而有助于儿童的词汇理解、记忆和泛化。未来相关研究应进一步扩大象似性手势的研究对象,考察象似性手势与具身认知的关系及其对儿童词汇学习的多方面影响,这将有助于提高未来研究成果对教育实践的指导作用。 展开更多
关键词 象似性手势 词汇学习 早期语言发展
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Regulation of extracellular signal-regulated kinase 1/2 influences hippocampal neuronal survival in a rat model of diabetic cerebral ischemia 被引量:10
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作者 Yaning Zhao Jianmin Li +4 位作者 Qiqun Tang pan zhang Liwei Jing Changxiang Chen Shuxing Li 《Neural Regeneration Research》 SCIE CAS CSCD 2014年第7期749-756,共8页
Activation of extracellular signal-regulated kinase 1/2 has been demonstrated in acute brain ischemia. We hypothesized that activated extracellular signal-regulated kinase 1/2 can protect hippocampal neurons from inju... Activation of extracellular signal-regulated kinase 1/2 has been demonstrated in acute brain ischemia. We hypothesized that activated extracellular signal-regulated kinase 1/2 can protect hippocampal neurons from injury in a diabetic model after cerebral ischemia/reperfusion. In this study, transient whole-brain ischemia was induced by four-vessel occlusion in normal and diabetic rats, and extracellular signal-regulated kinase 1/2 inhibitor (U0126) was administered into diabetic rats 30 minutes before ischemia as a pretreatment. Results showed that the number of surviving neurons in the hippocampal CA1 region was reduced, extracellular signal-regulated kinase 1/2 phosphorylation and KuT0 activity were decreased, and pro-apoptotic Bax expression was upregulated after intervention using U0126. These findings demonstrate that inhibition of extracellular signal-regulated kinase 1/2 activity aggravated neuronal loss in the hippocampus in a diabetic rat after cerebral ischemia/reperfusion, further decreased DNA repairing ability and ac- celerated apoptosis in hippocampal neurons. Extracellular signal-regulated kinase 1/2 activation plays a neuroprotective role in hippocampal neurons in a diabetic rat after cerebral ischemia/ reperfusion. 展开更多
关键词 nerve regeneration brain injury cerebral ischemia/reperfusion DNA dependent proteinkinase extracellular signal-regulated kinase Bax apoptosis HIPPOCAMPUS neural regeneration
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Protective effects of dl-3n-butylphthalide against diffuse brain injury 被引量:7
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作者 Yaning Zhao Jianmin Li +2 位作者 pan zhang Changxiang Chen Shuxing Li 《Neural Regeneration Research》 SCIE CAS CSCD 2013年第28期2615-2624,共10页
DI-3n-butyiphthalide can effectively treat cerebral ischemia; however, the mechanisms underlying the effects of dl-3n-butylphthalide on microcirculation disorders following diffuse brain injury remain unclear. In this... DI-3n-butyiphthalide can effectively treat cerebral ischemia; however, the mechanisms underlying the effects of dl-3n-butylphthalide on microcirculation disorders following diffuse brain injury remain unclear. In this study, models of diffuse brain injury were established in Sprague-Dawley rats with the vertical impact method. DI-3n-butylphthalide at 80 and 160 mg/kg was given via intraperitoneal injection immediately after diffuse brain injury. Ultrastructural changes in the cerebral cortex were observed using electron microscopy. Cerebral blood flow was measured by laser Doppler flowmetry, vascular density was marked by tannic acid-ferric chloride staining, vascular permeability was es- timated by the Evans blue method, brain water content was measured using the dry-wet method, and rat behavior was measured by motor function and sensory function tests. At 6, 24, 48, and 72 hours after administration of dl-3n-butylphthalide, reduced cerebral ultrastructure damage, in- creased vascular density and cerebral blood flow, and improved motor and sensory functions were observed. Our findings demonstrate that dl-3n-butylphthalide may have protective effects against diffuse brain injury by ameliorating microcirculation disorder and reducing blood-brain barrier dam- age and cerebral edema. 展开更多
关键词 neural regeneration brain injury diffuse brain injury blood-brain barrier brain edema vasculardensity cerebral blood flow vascular permeability brain water content grants-supported paper NEUROREGENERATION
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