Four 1,4-benzodioxane neolignans were first synthesized from pyrogallol, in which the Claisen rearrangement was used to afford three important C-6-C-3 units.
A novel reduction system is reported here in which the compounds with terminal C-C triple bond and disubstituted C-C triple bond react with NaBH4/Pd(PPh3)(4) in a base condition and only terminal C-C triple bond is re...A novel reduction system is reported here in which the compounds with terminal C-C triple bond and disubstituted C-C triple bond react with NaBH4/Pd(PPh3)(4) in a base condition and only terminal C-C triple bond is reduced.展开更多
A novel and efficient convergent synthesis of 13-demethyldeoxofaveline. a key intermediate for deoxofaveline, faveline and faveline methyl ether, was achieved by Wittig reaction and selective oxidation. And a novel si...A novel and efficient convergent synthesis of 13-demethyldeoxofaveline. a key intermediate for deoxofaveline, faveline and faveline methyl ether, was achieved by Wittig reaction and selective oxidation. And a novel sixteen-membered ring compound has been obtained in the meantime.展开更多
A ten-step synthesis of 7-deoxy-1,2,10,20-tetrahydrataxamairin B(5). a key precursor for taxamairin A(1), B(2), has been achieved. A Friedel-Crafts annunation is the key step.
Nimbidlol 1 and epi-6-oxonimbidiol 2 have been efficiently and stereospecifically synthesized from 3-isopropoxy-5,5-dimethyl-2-cyclohexenone and iodide 3 which are readily available.
基金the National Natural Science Foundation of China (No. 29772012)
文摘Four 1,4-benzodioxane neolignans were first synthesized from pyrogallol, in which the Claisen rearrangement was used to afford three important C-6-C-3 units.
基金the National Natural Science Foundation of China (No. 29772012)
文摘A novel reduction system is reported here in which the compounds with terminal C-C triple bond and disubstituted C-C triple bond react with NaBH4/Pd(PPh3)(4) in a base condition and only terminal C-C triple bond is reduced.
文摘A novel and efficient convergent synthesis of 13-demethyldeoxofaveline. a key intermediate for deoxofaveline, faveline and faveline methyl ether, was achieved by Wittig reaction and selective oxidation. And a novel sixteen-membered ring compound has been obtained in the meantime.
文摘A ten-step synthesis of 7-deoxy-1,2,10,20-tetrahydrataxamairin B(5). a key precursor for taxamairin A(1), B(2), has been achieved. A Friedel-Crafts annunation is the key step.
文摘Nimbidlol 1 and epi-6-oxonimbidiol 2 have been efficiently and stereospecifically synthesized from 3-isopropoxy-5,5-dimethyl-2-cyclohexenone and iodide 3 which are readily available.
