Intrapartum maternal normoglycemia seems to play an important role in the prevention of adverse perinatal, maternal and neonatal outcomes. Several glucose monitoring protocols have been developed, aiming to achieve a ...Intrapartum maternal normoglycemia seems to play an important role in the prevention of adverse perinatal, maternal and neonatal outcomes. Several glucose monitoring protocols have been developed, aiming to achieve a tight glucose monitoring and control. Depending on the type of diabetes and the optimal or suboptimal glycemic control, the treatment options include fasting status of the parturient, frequent monitoring of capillary blood glucose, intravenous dextrose infusion and subcutaneous or intravenous use of insulin. Continuous glucose monitoring system(CGMS) is a relatively new technology that measures interstitial glucose at very short time intervals over a specifi c period of time. The resulting profi le provides a more comprehensive measure of glycemic excursions than intermittent home blood glucose monitoring. Results of studies applying the CGMS technology in patients with or without diabetes mellitus(DM) have revealed new insights in glucose metabolism. Moreover, CGMS have a potential role in the improvement of glycemic control during pregnancy and labor, which may lead to a decrease in perinatal morbidity and mortality. In conclusion, the use of CGMS, with its important technical advantages compared to the conventional way of monitoring, may lead into a more etiological intrapartum management of both the mother and her fetus/infant in pregnancies complicated with DM.展开更多
Dear Editor,Human papillomavirus(HPV)is the most common sexually transmitted virus worldwide,and high-risk HPV infection is the most important risk factor for cervical cancer.1 However,few conclusive data are availabl...Dear Editor,Human papillomavirus(HPV)is the most common sexually transmitted virus worldwide,and high-risk HPV infection is the most important risk factor for cervical cancer.1 However,few conclusive data are available on the prevalence of the male HPV infection and its health consequences.It has been found that the prevalence of seminal HPV infection is higher in men with unexplained infertility,ranging between 10%and 35%compared with the general population(range:2%to 11%).2–4 In three recent systematic reviews,it was seen that HPV sperm infection may be associated with impaired sperm function that could lead to male infertility.2,4,5 HPV sperm infection with high-risk HPV among infertile men was shown to be associated with lower progressive sperm motility and higher DNA fragmentation index.6 Moreover,a high rate of pregnancy loss has been found among couples with HPV sperm infection after in vitro fertilization(IVF).7 In the majority of the studies performed to assess seminal HPV infection.展开更多
文摘Intrapartum maternal normoglycemia seems to play an important role in the prevention of adverse perinatal, maternal and neonatal outcomes. Several glucose monitoring protocols have been developed, aiming to achieve a tight glucose monitoring and control. Depending on the type of diabetes and the optimal or suboptimal glycemic control, the treatment options include fasting status of the parturient, frequent monitoring of capillary blood glucose, intravenous dextrose infusion and subcutaneous or intravenous use of insulin. Continuous glucose monitoring system(CGMS) is a relatively new technology that measures interstitial glucose at very short time intervals over a specifi c period of time. The resulting profi le provides a more comprehensive measure of glycemic excursions than intermittent home blood glucose monitoring. Results of studies applying the CGMS technology in patients with or without diabetes mellitus(DM) have revealed new insights in glucose metabolism. Moreover, CGMS have a potential role in the improvement of glycemic control during pregnancy and labor, which may lead to a decrease in perinatal morbidity and mortality. In conclusion, the use of CGMS, with its important technical advantages compared to the conventional way of monitoring, may lead into a more etiological intrapartum management of both the mother and her fetus/infant in pregnancies complicated with DM.
文摘Dear Editor,Human papillomavirus(HPV)is the most common sexually transmitted virus worldwide,and high-risk HPV infection is the most important risk factor for cervical cancer.1 However,few conclusive data are available on the prevalence of the male HPV infection and its health consequences.It has been found that the prevalence of seminal HPV infection is higher in men with unexplained infertility,ranging between 10%and 35%compared with the general population(range:2%to 11%).2–4 In three recent systematic reviews,it was seen that HPV sperm infection may be associated with impaired sperm function that could lead to male infertility.2,4,5 HPV sperm infection with high-risk HPV among infertile men was shown to be associated with lower progressive sperm motility and higher DNA fragmentation index.6 Moreover,a high rate of pregnancy loss has been found among couples with HPV sperm infection after in vitro fertilization(IVF).7 In the majority of the studies performed to assess seminal HPV infection.