Hepatocellular carcinoma(HCC)is the fifth most common cancer and the second most frequent cause of cancer-related death globally,with 854,000 new cases and 810,000 deaths yearly(1).
Nonalcoholic fatty liver disease(NAFLD)is one of the most common chronic liver disease worldwide.The septum of NAFLD ranges from simple steatosis to nonalcoholic steatohepatitis,the latter of which may further progres...Nonalcoholic fatty liver disease(NAFLD)is one of the most common chronic liver disease worldwide.The septum of NAFLD ranges from simple steatosis to nonalcoholic steatohepatitis,the latter of which may further progress to liver cirrhosis and even more advanced stages in 20%patients(1,2).During last decade,nonalcoholic steatohepatitis has been identified as the most rapidly growing indication for liver transplantation in patients with hepatocellular carcinoma in the United States(3).Meanwhile,NAFLD also significantly increases risk of cardiovascular diseases,type 2 diabetes,chronic kidney disease,and colorectal neoplasia.展开更多
文摘Hepatocellular carcinoma(HCC)is the fifth most common cancer and the second most frequent cause of cancer-related death globally,with 854,000 new cases and 810,000 deaths yearly(1).
基金This study was supported by the Key Research Development Program of Zhejiang Province(2018C03018)the Traditional Chinese Medicine Scientific Research Fund Project of Zhejiang Province(2017ZA079).
文摘Nonalcoholic fatty liver disease(NAFLD)is one of the most common chronic liver disease worldwide.The septum of NAFLD ranges from simple steatosis to nonalcoholic steatohepatitis,the latter of which may further progress to liver cirrhosis and even more advanced stages in 20%patients(1,2).During last decade,nonalcoholic steatohepatitis has been identified as the most rapidly growing indication for liver transplantation in patients with hepatocellular carcinoma in the United States(3).Meanwhile,NAFLD also significantly increases risk of cardiovascular diseases,type 2 diabetes,chronic kidney disease,and colorectal neoplasia.
