The nuclear factor kappa B (NF-κB) transcription factor coordinates several aspects of innate and adaptive immunity, inflammation, cell survival and proliferation . Dysregulation of the NF-κB pathway has been asso...The nuclear factor kappa B (NF-κB) transcription factor coordinates several aspects of innate and adaptive immunity, inflammation, cell survival and proliferation . Dysregulation of the NF-κB pathway has been associated with cancer development and progression as well as with other human diseases including viral infections and a number of inflammatory diseases .展开更多
文摘The nuclear factor kappa B (NF-κB) transcription factor coordinates several aspects of innate and adaptive immunity, inflammation, cell survival and proliferation . Dysregulation of the NF-κB pathway has been associated with cancer development and progression as well as with other human diseases including viral infections and a number of inflammatory diseases .