We recently published a review of the factors under-lying the winter seasonality and pathogenicity of respira-tory viruses[1].We showed that many respiratory viruses possess natural thermal sensitivity,meaning they re...We recently published a review of the factors under-lying the winter seasonality and pathogenicity of respira-tory viruses[1].We showed that many respiratory viruses possess natural thermal sensitivity,meaning they repli-cate faster at temperatures below their hosts’normal body temperature,confining them to the upper airways.Our hypothesis suggests that this tropism gives the virus two important advantages:(1)it is well-placed to be transmit-ted;and(2)it is less likely to immobilize its host,increas-ing transmission.展开更多
文摘We recently published a review of the factors under-lying the winter seasonality and pathogenicity of respira-tory viruses[1].We showed that many respiratory viruses possess natural thermal sensitivity,meaning they repli-cate faster at temperatures below their hosts’normal body temperature,confining them to the upper airways.Our hypothesis suggests that this tropism gives the virus two important advantages:(1)it is well-placed to be transmit-ted;and(2)it is less likely to immobilize its host,increas-ing transmission.
