Bacterial sensing is important for understanding the numerous roles bacteria play in nature and in technology,understanding and managing bacterial populations,detecting pathogenic bacterial infections,and preventing t...Bacterial sensing is important for understanding the numerous roles bacteria play in nature and in technology,understanding and managing bacterial populations,detecting pathogenic bacterial infections,and preventing the outbreak of illness.Current analytical challenges in bacterial sensing center on the dilemma of rapidly acquiring quantitative information about bacteria with high detection efficiency,sensitivity,and specificity,while operating within a reasonable budget and optimizing the use of ancillary tools,such as multivariate statistics.This review starts from a general description of bacterial sensing methods and challenges,and then focuses on bacterial characterization using optical methods including Raman spectroscopy and imaging,infrared spectroscopy,fluorescence spectroscopy and imaging,and plasmonics,including both extended and localized surface plasmon resonance spectroscopy.The advantages and drawbacks of each method in relation to the others are discussed,as are their applications.A particularly promising direction in bacterial sensing lies in combining multiple approaches to achieve multiplex analysis,and examples where this has been achieved are highlighted.展开更多
With roots reaching back to the eighteenth century and pros-pects as new as the development of advanced energy storage technologies,electrochemistry is at once both old and new.With a history of development as long as...With roots reaching back to the eighteenth century and pros-pects as new as the development of advanced energy storage technologies,electrochemistry is at once both old and new.With a history of development as long as this,electrochem-istry’s obituary has been written multiple times.Neverthe-less,this fascinating science focused on understanding and manipulating electron transfer reactions continues to spawn new areas of application and fascinating fundamental dis-coveries.That is why it is such a pleasure to create and introduce this excellent collection of articles for the Jour-nal of Analysis and Testing.Composed of contributions that literally circle the globe-from Asia,Europe,and North America-these papers serve as a guide to some of the most recent and exciting new developments in electrochemistry,generally,and electroanalysis specifically.展开更多
基金the National Institute of Allergies and Infectious Diseases under Grant 1RO1AI113219-01.
文摘Bacterial sensing is important for understanding the numerous roles bacteria play in nature and in technology,understanding and managing bacterial populations,detecting pathogenic bacterial infections,and preventing the outbreak of illness.Current analytical challenges in bacterial sensing center on the dilemma of rapidly acquiring quantitative information about bacteria with high detection efficiency,sensitivity,and specificity,while operating within a reasonable budget and optimizing the use of ancillary tools,such as multivariate statistics.This review starts from a general description of bacterial sensing methods and challenges,and then focuses on bacterial characterization using optical methods including Raman spectroscopy and imaging,infrared spectroscopy,fluorescence spectroscopy and imaging,and plasmonics,including both extended and localized surface plasmon resonance spectroscopy.The advantages and drawbacks of each method in relation to the others are discussed,as are their applications.A particularly promising direction in bacterial sensing lies in combining multiple approaches to achieve multiplex analysis,and examples where this has been achieved are highlighted.
文摘With roots reaching back to the eighteenth century and pros-pects as new as the development of advanced energy storage technologies,electrochemistry is at once both old and new.With a history of development as long as this,electrochem-istry’s obituary has been written multiple times.Neverthe-less,this fascinating science focused on understanding and manipulating electron transfer reactions continues to spawn new areas of application and fascinating fundamental dis-coveries.That is why it is such a pleasure to create and introduce this excellent collection of articles for the Jour-nal of Analysis and Testing.Composed of contributions that literally circle the globe-from Asia,Europe,and North America-these papers serve as a guide to some of the most recent and exciting new developments in electrochemistry,generally,and electroanalysis specifically.