The objective was to assess the impact on health due to the exposure to air pollution derived from the renewal of the urban bus fleet in S?o Paulo. The study analyzed the substitution of the bus fleet through the vari...The objective was to assess the impact on health due to the exposure to air pollution derived from the renewal of the urban bus fleet in S?o Paulo. The study analyzed the substitution of the bus fleet through the variation of the concentration of atmospheric pollutants such as PM10 in the municipality of S?o Paulo and its associated health’s benefits values compared to the investments performed in the bus fleet renewal. PM10 average annual reduction due to the bus improvement system resulted on 22.3%. A cost-benefit evaluation considered the renewal investments’ costs compared to the obtained valued health benefits and it resulted in 4.31. Although the result may suggest a not viable investment, it must be observed that air pollution reduction favors health impacts and that this relation could be improved if additional investments on sustainable transportation increase.展开更多
This study investigated the effects on the reproductive system of balb-c mice exposed to water collected from different sources near to a deactivated fertilizer waste depositary. Eighty male mice were separated in fou...This study investigated the effects on the reproductive system of balb-c mice exposed to water collected from different sources near to a deactivated fertilizer waste depositary. Eighty male mice were separated in four groups: Group A (mineral water);Group B (water from the water treatment station);Group C (water from Cubatao city);Group D (water from the waste depositary region). They were exposed to water since they were weaned until they reached sexual maturity, then they were coupled with females in reproductive age and after this mating time they were sacrificed. The evaluated parameters were testicle weight, sperm analysis, pregnancy rate, sex ratio of the offspring and Sertoli cell count. The analysis of the water did not show presence of pollutants in the Group “A” and Group “C” water. Group “B” showed low level of cadmium, 3.58 ± 0.50 μg/L. Group “D” showed the presence of PAH’s and high levels of lead (221 ± 16 μg/L), cadmiun (12.6 ± 1.2 μg/L) and mercury (5.3 ± 1.1 μg/L). The tests of Levene and Kolmogorov-Smirnov were employed to verify the homogeneity of the variances and the tack to the normal curve, respectively. ANOVA was used for parametric tests and Kruskall-Wallis was used for non-parametric tests, while Turkey tests were employed for multiple comparisons. There were no differences between groups in testicle weight, sperm analysis, pregnancy rate and Sertoli cell count. There was a significant reduction in sex-ratio of the offspring in Group B. This alteration cannot be explained by the cadmium levels in Group B water. In the present study we cannot associate the exposition to contaminated water from the waste depositary and reproductive alterations.展开更多
Studies have investigated the effects of heat and temperature variability(TV)on mortality.However,few assessed whether TV modifies the heat-mortality association.Data on daily temperature and mortality in the warm sea...Studies have investigated the effects of heat and temperature variability(TV)on mortality.However,few assessed whether TV modifies the heat-mortality association.Data on daily temperature and mortality in the warm season were collected from 717 locations across 36 countries.TV was calculated as the standard deviation of the average of the same and previous days’minimum and maximum temperatures.展开更多
文摘The objective was to assess the impact on health due to the exposure to air pollution derived from the renewal of the urban bus fleet in S?o Paulo. The study analyzed the substitution of the bus fleet through the variation of the concentration of atmospheric pollutants such as PM10 in the municipality of S?o Paulo and its associated health’s benefits values compared to the investments performed in the bus fleet renewal. PM10 average annual reduction due to the bus improvement system resulted on 22.3%. A cost-benefit evaluation considered the renewal investments’ costs compared to the obtained valued health benefits and it resulted in 4.31. Although the result may suggest a not viable investment, it must be observed that air pollution reduction favors health impacts and that this relation could be improved if additional investments on sustainable transportation increase.
文摘This study investigated the effects on the reproductive system of balb-c mice exposed to water collected from different sources near to a deactivated fertilizer waste depositary. Eighty male mice were separated in four groups: Group A (mineral water);Group B (water from the water treatment station);Group C (water from Cubatao city);Group D (water from the waste depositary region). They were exposed to water since they were weaned until they reached sexual maturity, then they were coupled with females in reproductive age and after this mating time they were sacrificed. The evaluated parameters were testicle weight, sperm analysis, pregnancy rate, sex ratio of the offspring and Sertoli cell count. The analysis of the water did not show presence of pollutants in the Group “A” and Group “C” water. Group “B” showed low level of cadmium, 3.58 ± 0.50 μg/L. Group “D” showed the presence of PAH’s and high levels of lead (221 ± 16 μg/L), cadmiun (12.6 ± 1.2 μg/L) and mercury (5.3 ± 1.1 μg/L). The tests of Levene and Kolmogorov-Smirnov were employed to verify the homogeneity of the variances and the tack to the normal curve, respectively. ANOVA was used for parametric tests and Kruskall-Wallis was used for non-parametric tests, while Turkey tests were employed for multiple comparisons. There were no differences between groups in testicle weight, sperm analysis, pregnancy rate and Sertoli cell count. There was a significant reduction in sex-ratio of the offspring in Group B. This alteration cannot be explained by the cadmium levels in Group B water. In the present study we cannot associate the exposition to contaminated water from the waste depositary and reproductive alterations.
基金HaK was supported by the National Natural Science Foundation of China(92043301,82030103,and 91843302)and China Medical Board Collaborating Program(16-250)AG and FS were supported by the Medical Research Council,UK(MK/M022625/1)+10 种基金the Natural Environment Research Council,UK(NE/R009384/1)and the European Union's Horizon 2020 Project Exhaustion(820655)VH was supported by the Spanish Ministry of Science and Innovation(PCIN-2017-046)and the German Federal Ministry of Education and Research(01 LSI201A2)YH and MH were supported by the Environment Research and Technology Development Fund(JPMEERF15S11412)the Environmental Restoration and Conservation Agency,Japan.JK and AU were supported by the Czech Science Foundation(18-22125S)ST was supported by the Shanghai Municipal Science and Technology Commission(18411951600)Y-LLG was supported by a Career Development Fellowship of the Australian National Health and Medical Research Council(APP1163693)SL was supported by an Early Career Fellowship of the Australian National Health and Medical Research Council(APP1109193)JJKJJ and NR were supported by the Academy of Finland(310372)The funders had no role in considering the study design or in the collection,analysis,interpretation of data,writing of the report,or decision to submit the article for publication.
基金This study was supported by the Australian Research Council(DP210102076)the Australian National Health and Medical Research Council(APP2000581)+12 种基金Y.W and B.W.were supported by the China Scholarship Council(nos.202006010044 and 202006010043)S.L.was supported by an Emerging Leader Fellowship of the Australian National Health and Medical Research Council(no.APP2009866)Y.G.was supported by Career Development Fellowship(no.APP1163693)and Leader Fellowship(no.APP2008813)of the Australian National Health and Medical Research CouncilJ.K.and A.U.were supported by the Czech Science Foundation(project no.20-28560S)N.S.was supported by the National Institute of Environmental Health Sciences-funded HERCULES Center(no.P30ES019776)Y.H.was supported by the Environment Research and Technology Development Fund(JPMEERF15S11412)of the Environmental Restoration and Conservation AgencyM.d.S.Z.S.C.and P.H.N.S.were supported by the São Paulo Research Foundation(FAPESP)H.O.and E.I.were supported by the Estonian Ministry of Education and Research(IUT34-17)J.M.was supported by a fellowship of Fundação para a Ciência e a Tecnlogia(SFRH/BPD/115112/2016)A.G.and F.S.were supported by the Medical Research Council UK(grant ID MR/R013349/1),the Natural Environment Research Council UK(grant ID NE/R009384/1),and the EU’s Horizon 2020 project,Exhaustion(grant ID 820655)A.S.and F.d.D.were supported by the EU’s Horizon 2020 project,Exhaustion(grant ID 820655)V.H.was supported by the Spanish Ministry of Economy,Industry and Competitiveness(grant ID PCIN-2017-046)A.T.byMCIN/AEI/10.13039/501100011033(grant CEX2018-000794-S).Statistics South Africa kindly provided the mortality data,but had no other role in the study.
文摘Studies have investigated the effects of heat and temperature variability(TV)on mortality.However,few assessed whether TV modifies the heat-mortality association.Data on daily temperature and mortality in the warm season were collected from 717 locations across 36 countries.TV was calculated as the standard deviation of the average of the same and previous days’minimum and maximum temperatures.
