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The aryl hydrocarbon receptor and the gut–brain axis 被引量:4
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作者 Andreia Barroso João Vitor Mahler +1 位作者 pedro henrique fonseca-castro Francisco J.Quintana 《Cellular & Molecular Immunology》 SCIE CAS CSCD 2021年第2期259-268,共10页
The aryl hydrocarbon receptor(AHR)is a ligand-activated transcription factor initially identified as the receptor for dioxin.Almost half a century after its discovery,AHR is now recognized as a receptor for multiple p... The aryl hydrocarbon receptor(AHR)is a ligand-activated transcription factor initially identified as the receptor for dioxin.Almost half a century after its discovery,AHR is now recognized as a receptor for multiple physiological ligands,with important roles in health and disease.In this review,we discuss the role of AHR in the gut–brain axis and its potential value as a therapeutic target for immune-mediated diseases. 展开更多
关键词 Aryl hydrocarbon receptor Autoimmune diseases Infectious diseases CANCER
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