To the Editor:Extragonadal,nongestational choriocarcinomas are very rare neoplasms that mostly arise spontaneously in midline structures,such as the retroperitoneum,mediastinum,and vicinity of the pineal body,but they...To the Editor:Extragonadal,nongestational choriocarcinomas are very rare neoplasms that mostly arise spontaneously in midline structures,such as the retroperitoneum,mediastinum,and vicinity of the pineal body,but they also have been reported in other visceral organs,such as the stomach,esophagus,small bowel,prostate, and urinary bladder. In the last seven decades,there have been only 29 cases of male primary pulmonary choriocarcinoma (PPC) reported in the literature.Extragonadal choriocarcinoma arising in the lung is thought to be unresponsive to treatment and is associated with a poor prognosis.We report a 71-year-old male patient with extragonadal,nongestational choriocarcinoma apparently arising in the lung and review the characteristics of previously reported cases to explore the diagnosis and treatment of primary choriocarcinoma of the lung.展开更多
基金the grants from the National Natural Science Foundation of China (No.81700028)Jiangsu Provincial Natural Science Foundation (No.SBK2017042749)+1 种基金Jiangsu Provincial Health and Family Planning Commission Foundation (No.Q2017001)Jiangsu Provincial Young Medical Talent Program (No.QNRC2016600).
文摘To the Editor:Extragonadal,nongestational choriocarcinomas are very rare neoplasms that mostly arise spontaneously in midline structures,such as the retroperitoneum,mediastinum,and vicinity of the pineal body,but they also have been reported in other visceral organs,such as the stomach,esophagus,small bowel,prostate, and urinary bladder. In the last seven decades,there have been only 29 cases of male primary pulmonary choriocarcinoma (PPC) reported in the literature.Extragonadal choriocarcinoma arising in the lung is thought to be unresponsive to treatment and is associated with a poor prognosis.We report a 71-year-old male patient with extragonadal,nongestational choriocarcinoma apparently arising in the lung and review the characteristics of previously reported cases to explore the diagnosis and treatment of primary choriocarcinoma of the lung.
