Dear Editor,In the adult brain,the transition from neural stem cell(NSC)quiescence to activation is a focal regulatory point for neural regeneration and dysregulations in the transition lead to brain disorders.1,2 Dur...Dear Editor,In the adult brain,the transition from neural stem cell(NSC)quiescence to activation is a focal regulatory point for neural regeneration and dysregulations in the transition lead to brain disorders.1,2 During this transition,both cell cycle states and metabolism including mitochondria undergo extensive reprogramming.A deep understanding of such comprehensive changes is a prerequisite for a holistic picture of physiology and may aid disease combats.展开更多
基金This work was supported by funds from the National Key R&D Program of China(2019YFA0110300,2017YFA0104100)Shanghai Easter Scholar(8101219003)to Z.L.G.+2 种基金the National Natural Science Foundation of China(31600819 to C.H.C.,81773302 to Y.T.F.,31571058 and 32070862 to Z.L.G.,31701282 to M.J.,and 81901031 to X.X.H.)Shanghai Municipal Planning Commission of science and Research Fund(20174Y0216)to C.C.H.the Natural Science Foundation of Shanghai(19ZR1445400)to X.X.H.
文摘Dear Editor,In the adult brain,the transition from neural stem cell(NSC)quiescence to activation is a focal regulatory point for neural regeneration and dysregulations in the transition lead to brain disorders.1,2 During this transition,both cell cycle states and metabolism including mitochondria undergo extensive reprogramming.A deep understanding of such comprehensive changes is a prerequisite for a holistic picture of physiology and may aid disease combats.
