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Bioinspired membrane-based nanomodulators for immunotherapy of autoimmune and infectious diseases 被引量:1
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作者 Yesi Shi Hongyan Qian +4 位作者 peishi rao Dan Mu Yuan Liu Gang Liu Zhongning Lin 《Acta Pharmaceutica Sinica B》 SCIE CAS CSCD 2022年第3期1126-1147,共22页
Autoimmune or infectious diseases often instigate the undesirable damages to tissues or organs to trigger immune-related diseases,which involve plenty of immune cells,pathogens and autoantibodies.Nanomedicine has a gr... Autoimmune or infectious diseases often instigate the undesirable damages to tissues or organs to trigger immune-related diseases,which involve plenty of immune cells,pathogens and autoantibodies.Nanomedicine has a great potential in modulating immune system.Particularly,biomimetic nanomodulators can be designed for prevention,diagnosis and therapy to achieve a better targeted immunotherapy.With the development of materials science and bioengineering,a wide range of membranecoated nanomodulators are available.Herein,we summarize recent advancements of bioinspired membrane-coated nanoplatform for systemic protection against immune-related diseases including autoimmune and infectious diseases.We also rethink the challenges or limitations in the progress of the therapeutic nanoplatform,and discuss the further application of the nanomodulators in the view of translational medicine for combating immune-related diseases. 展开更多
关键词 Biomimetic membrane Nanomodulators Immune system BIOENGINEERING IMMUNOTHERAPY AUTOIMMUNE Infectious diseases
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