体育案例研究的学理基础、基本要素与中国探索

案例研究是知识生产与理论建构的重要科学途径。相较管理学等相关学科的案例研究,体育学科兼具人文社会科学和自然科学的交叉性,为丰富体育案例的研究对象、分析内容及举证方式提供了学理基础。从案例实践到理论构建的转换过程,可基于发现独特案例,在已有体育知识基础上进行体育知识生产;也可直面已有体育知识局限,以独特案例为载体,进行体育知识生产。从学理层面分析,体育案例研究应以独特实践为主要来源,以发现问题为主要驱动,以服务教学为主要诉求,以规范流程为主要保障及以学科交叉为主要特征夯实学理基础。在此基础上,形成了具有体育学学科特色和体育实践特点的学科内涵、研究对象、基本范式、研究过程、研究工具等体育案例研究基本要素。从实践探索视角,未来开展中国特色体育案例研究,应以提出体育实践的“真问题”为导向开展研究选题,以挖掘体育实践的“真素材”为手段进行研究论证,以进入体育实践的“真情境”为途径实施研究过程,及以提炼中国体育的“真理论”为目标彰显其研究价值。

盆底重建术后泌尿道网片/吊带暴露的手术处理——单中心经验

目的对盆底重建术后网片/吊带泌尿道暴露的手术干预方法及长期治疗结局进行分析探讨。方法对2011年11月—2020年9月四川大学华西医院泌尿外科收治的因经阴道盆底重建术后网片或吊带发生泌尿道暴露再次接受手术治疗的9例患者的临床资料进行回顾性分析,探讨其一般临床特点,再次手术方式及治疗结局。结果9例患者的中位年龄为53(39~73)岁,身体质量指数中位数为23.0(19.5~27.3)。6例患者既往因盆腔脏器脱垂接受经阴道网片植入术而于术后发生网片暴露,其中3例患者接受经阴道部分网片切除术、3例接受膀胱镜下钬激光消融手术。另外3例患者既往因尿失禁接受无张力尿道中段悬吊术而于术后发生吊带暴露,其中2例接受膀胱镜下部分网片切除术治疗,1例接受膀胱镜下钬激光消融手术治疗。9例患者的中位随访时间为69(16~121)个月。截至末次随访时所有患者均未再次发生网片暴露。结论经阴道途径及经尿道途径的网片/吊带切除术均是治疗盆底重建术后泌尿道网片/吊带暴露的有效手术方法。

何以推动基层体育运动学校转型发展——以京山市体校改革为例

面对我国基层体校总体规模下降及青少年体育后备人才培养质量下降等问题,以京山市体校改革为案例,以青少年体育后备人才培养需求及基层体校转型发展要素为切口,深入分析基层体校发展的现实壁垒,系统探索推动基层体校转型发展的实践路径与内在逻辑。经研究认为,促进基层体校转型发展需要实现办学理念、培养目标、资源供给、运行机制等多维度要素融合;形成文体双优办学新模式、构建后备人才选育新体系、优化办学资源配置新路径、激发后备人才培养新活力;其核心理论运作逻辑体现为以刚性法律法规构建基层体校转型发展框架,以柔性治理方式优化基层体校转型发展环境,以高效培养机制畅通基层体校转型发展流程,三重驱动我国基层体校实现高质量转型发展。

NFT Security Matrix:Towards Modeling NFT Ecosystem Threat

Digital assets have boomed over the past few years with the emergence of Non-fungible Tokens(NFTs).To be specific,the total trading volume of digital assets reached an astounding$55.5 billion in 2022.Nevertheless,numerous security concerns have been raised by the rapid expansion of the NFT ecosystem.NFT holders are exposed to a plethora of scams and traps,putting their digital assets at risk of being lost.However,academic research on NFT security is scarce,and the security issues have aroused rare attention.In this study,the NFT ecological process is comprehensively explored.This process falls into five different stages encompassing the entire lifecycle of NFTs.Subsequently,the security issues regarding the respective stage are elaborated and analyzed in depth.A matrix model is proposed as a novel contribution to the categorization of NFT security issues.Diverse data are collected from social networks,the Ethereum blockchain,and NFT markets to substantiate our claims regarding the severity of security concerns in the NFT ecosystem.From this comprehensive dataset,nine key NFT security issues are identified from the matrix model and then subjected to qualitative and quantitative analysis.This study aims to shed light on the severity of NFT ecosystem security issues.The findings stress the need for increased attention and proactive measures to safeguard the NFT ecosystem.

Positive Solutions for a Class of Quasilinear Schrödinger Equations with Nonlocal Term

This paper is considered the existence of positive solutions for a class of generalized quasilinear Schrödinger equations with nonlocal term in RN which have appeared from plasma physics, as well as high-power ultrashort laser in matter. We use a charge of variables and obtain the existence of solutions via minimization argument.

Erratum to “Positive Solutions for a Class of Quasilinear Schrödinger Equations with Nonlocal Term” [Journal of Applied Mathematics and Physics (2022) 347-359]

The original online version of this article (Liao, P., Ping, R. and Chen, S. (2022) Positive Solutions for a Class of Quasilinear Schrödinger Equations with Nonlocal Term. Journal of Applied Mathematics and Physics, 10, 347-359. https://doi.org/10.4236/jamp.2022.102027) needs some further amendments and clarification.

Aflatoxin B1, zearalenone and deoxynivalenol in feed ingredients and complete feed from different Province in China

Background： The current study was carried out to provide a reference for monitory of aflatoxin B_1（AFB_1）,zearalenone（ZEN） and deoxynivalenol（DON） contamination in feed ingredients and complete feeds were collected from different Province in China from 2013 to 2015.Methods： A total of 443 feed ingredients, including 220 corn, 24 wheat, 24 domestic distillers dried grains with soluble（DDGS）, 55 bran, 20 wheat shorts and red dog, 37 imported DDGS, 34 corn germ meal and 29 soybean meal as well as 127 complete feeds including 25 pig complete feed（powder）, 90 pig complete feed（pellet）, six duck complete feed and six cattle complete feed were randomly collected from different Province in China,respectively, by high-performance chromatography in combined with UV or fluorescence analysis.Results： The incidence rates of AFB_1, ZEN and DON contamination of feed ingredients and complete feeds were80.8, 92.3 and 93.9 %, respectively. The percentage of positive samples for DON ranged from 66.7 to 100 %.Domestic DDGS and imported DDGS presented the most serious contamination AFB_1, ZEN and DON contamination levels of feeds ranged from 61.5 to 100 %, indicated that serious contamination over the studied 3-year period.Conclusion： The current data provide clear evidence that AFB_1, ZEN and DON contamination of feed ingredients and complete feeds in different Province in China is serious and differs over past 3-year. The use of corn, domestic DDGS, imported DDGS and corn germ meal, which may be contaminated with these three mycotoxins, as animal feed may triggered a health risk for animal. Feeds are most contaminated with DON followed by ZEN and AFB_1.Mycotoxins contamination in feed ingredients and complete feeds should be monitored routinely in China.

Cloning and expression analysis of GhDET3, a vacuolar H^+-ATPase subunit C gene, from cotton

Vacuolar H^+-ATPase was regarded as a key enzyme promoting the fiber cell elongation in cotton (Gossypium hirsuturm L.) through regulating turgor-driven pressure involved in polarity expansion of single cell fiber. The DET3, a V-ATPase subunit C, plays an important role in assembling subunits and regulating the enzyme activity, and is involved in Brassinosteroid-induced cell elongation. To analyze the function of GhDET3 on the elongation of cotton fibers, seven candidates of ESTs were screened and contigged for a 5'-upstream sequence, and the 3'-RACE technique was used to clone the 3'-downstream sequence for the full length of GhDET3 gene. The full length of the target clone was 1,340 bp, including a 10 bp 5'-UTR, an ORF of 1,134 bp, and a 196 bp 3'-UTR. This cDNA sequence encoded a polypepide of 377 amino acid residues with a predicted molecular mass of 43 kDa and a basic isoelectric point of 5.58. Furthermore, a length of 3,410 bp sequence from genomic DNA of GhDET3 was also cloned by PCR. The deduced amino acid sequence had a high homology with DET3 from Arabidopsis, rice, and maize. Quantitative real-time PCR (qRT-PCR) analysis showed that the GhDET3 expression pattern was ubiquitous in all the tissues and organs detected. The result also revealed that the accumulation of GhDET3 mRNA reached the highest profile at the fiber elongation stage in 12 DPA (days post anthesis) fibers, compared with the lowest level at the fiber initiation stage in 0 DPA ovules (with fibers). The transcript accumulation in fibers and ovules shared the similar variation tendency. In addition, in vitro ovule culture experiment demonstrated that exogenous 24-EBL treatment to 4 DPA ovules (with fibers) was capable of increasing the expression level of GhDET3, and the mRNA accumulation of GhDET3 increased in transgenic FBP7::GhDET2 cotton fibers in vivo. These results indicate that GhDET3 gene plays a crucial role in cotton fiber elongation.

基于AS 5100.2标准的铁路桥梁垂向活载校核计算研究及应用

介绍了澳大利亚标准AS 5100.2:2017的铁路桥梁基准活载等级及其他等级活载图式,提出了桥梁在标准活载和评估车辆载荷作用下所受最大静态剪力和弯矩的计算方法,并推导了相关的计算公式;采用Visual Basic语言编写了校核计算程序,并对计算程序的正确性进行了验证。验证计算和运用实例表明,文章所述计算方法正确,程序计算精度满足实际需求,能够有效指导出口澳大利亚铁路货车设计。

Optimization of Electricity Purchase and Sales Strategies of Electricity Retailers under the Condition of Limited Clean Energy Consumption

In the process of my country’s energy transition,the clean energy of hydropower,wind power and photovoltaic power generation has ushered in great development,but due to the randomness and volatility of its output,it has caused a certain waste of clean energy power generation resources.Regarding the purchase and sale of electricity by electricity retailers under the condition of limited clean energy consumption,this paper establishes a quantitative model of clean energy restricted electricity fromthe perspective of power system supply and demand balance.Then it analyzes the source-charge dual uncertain factors in the electricity retailer purchasing and selling scenarios in the mid-to long-term electricity market and the day-ahead market.Through the multi-scenario analysis method,the uncertain clean energy consumption and the user’s power demand are combined to form the electricity retailer’s electricity purchase and sales scene,and the typical scene is obtained by using the hierarchical clustering algorithm.This paper establishes a electricity retailer’s risk decisionmodel for purchasing and selling electricity in themid-and long-term market and reduce-abandonment market,and takes the maximum profit expectation of the electricity retailer frompurchasing and selling electricity as the objective function.At the same time,in themediumand longterm electricity market and the day-ahead market,the electricity retailer’s purchase cost,electricity sales income,deviation assessment cost and electricity purchase and sale risk are considered.The molecular results show that electricity retailers can obtain considerable profits in the reduce-abandonment market by optimizing their own electricity purchase and sales strategies,on the premise of balancing profits and risks.

Existence of the Solutions for a Class of Quasilinear Schrödinger Equations with Nonlocal Term

In this paper, we deal with the existence of solution for a class of quasilinear Schrödinger equations with a nonlocal term Where μ ∈ (0,3), the function K,V ∈ C(R3,R+) and V(x) may be vanish at infinity, g is a C1 even function with g’(t) ≤ 0 for all t ≥ 0, g(0) = 1, , 0 a F is the primitive function of f which is superlinear but subcritical at infinity in the sense of Hardy-littlewood-Sobolev inequality. By the mountain pass theorem, we prove that the above equation has a nontrivial solution.

铁路轻油类罐车卸油装置研制

根据国外大型矿区对铁路轻油类罐车装卸需求,研制一种下部卸油装置。通过分析国外下卸式卸油装置特点,确定卸油装置结构和关键部件,开展密封性试验并完成研制工作。研制并运用下卸式罐车,对解决我国轻油类罐车装卸存在的问题具有一定借鉴意义。

Mitochondrial dysfunction:mechanisms and advances in therapy

Mitochondria,with their intricate networks of functions and information processing,are pivotal in both health regulation and disease progression.Particularly,mitochondrial dysfunctions are identified in many common pathologies,including cardiovascular diseases,neurodegeneration,metabolic syndrome,and cancer.However,the multifaceted nature and elusive phenotypic threshold of mitochondrial dysfunction complicate our understanding of their contributions to diseases.Nonetheless,these complexities do not prevent mitochondria from being among the most important therapeutic targets.In recent years,strategies targeting mitochondrial dysfunction have continuously emerged and transitioned to clinical trials.Advanced intervention such as using healthy mitochondria to replenish or replace damaged mitochondria,has shown promise in preclinical trials of various diseases.Mitochondrial components,including mtDNA,mitochondria-located microRNA,and associated proteins can be potential therapeutic agents to augment mitochondrial function in immunometabolic diseases and tissue injuries.Here,we review current knowledge of mitochondrial pathophysiology in concrete examples of common diseases.We also summarize current strategies to treat mitochondrial dysfunction from the perspective of dietary supplements and targeted therapies,as well as the clinical translational situation of related pharmacology agents.Finally,this review discusses the innovations and potential applications of mitochondrial transplantation as an advanced and promising treatment.

High-performance Ti_(3)C_(2)T_(x)achieved by polyaniline intercalation and gelatinization as a high-energy cathode for zinc-ion capacitor

The actual manufacture of supercapacitors(SCs)is restricted by the inadequate energy density,and the energy density of devices can be properly promoted by assembling zinc-ion capacitors(ZICs)which used capacitive cathode and battery-type anode.Two-dimensional(2D)MXene has brought great focuses in the electrode research on the foundation of large redox-active surface,but the specific capacitance is still affected by the tight stacking of interlaminations.Ti_(3)C_(2)T_(x)@polyaniline(PANI)heterostructures are prepared by uniformly depositing the conductive polymer PANI nanorods as the intercalation agent into the external of Ti_(3)C_(2)T_(x)nanosheets to inhibit stacking.Subsequently,by using graphene oxide(GO)-assisted low-temperature hydrothermal self-assembly manufacture,2D heterostructures are assembled into the three-dimensional(3D)porous crosslinked Ti_(3)C_(2)T_(x)@PANI-reduced graphene oxide(RGO)hydrogels.Attributed to the synergistic work of PANI nanorods,Ti_(3)C_(2)T_(X)nanosheets,and 3D crosslinking frameworks of RGO to match capacitive and battery effects,3D porous hierarchical Ti_(3)C_(2)T_(x)@PANI-RGO heterostructure hydrogels have rich ion transport channels,a large number of active sites,and excellent reaction kinetics.ZIC is assembled by using Ti_(3)C_(2)T_(x)@PANI-RGO heterostructure hydrogels as cathodes and zinc foil as anodes.In this work,Ti_(3)C_(2)T_(x)@PANI-RGO//Zn ZIC exhibits a wide working window(2.0 V),marked specific capacitance(589.89 F·g^(−1)at 0.5 A·g−1),salient energy density(327.71 Wh·kg^(−1)at 513.61 W·kg^(−1)and 192.20 Wh·kg^(−1)at 13,005.87 W·kg^(−1)),and durable cycling stability(97.87%capacitance retention after 10,000 cycles at 10 A·g^(−1)).This study emphasizes the device design of ZICs and the broad prospect of Ti_(3)C_(2)T_(x)-based hydrogels as viable cathodes for ZICs.

Trimethylamine oxide supplementation differentially regulates fat deposition in liver,longissimus dorsi muscle and adipose tissue of growing-finishing pigs

Trimethylamine oxide(TMAO)is a microbiota-derived metabolite,and numerous studies have shown that it could regulate fat metabolism in humans and mice.However,few studies have focused on the effects of TMAO on fat deposition in growing-finishing pigs.This study aimed to investigate the effect of TMAO on fat deposition and intestinal microbiota in growing-finishing pigs.Sixteen growing pigs were randomly divided into 2 groups and fed with a basal diet with 0 or 1 g/kg TMAO for 149 d.The intestinal microbial profiles,fat deposition indexes,and fatty acid profiles were measured.These results showed that TMAO supplementation had a tendency to decrease lean body mass(P<0.10)and significantly increased backfat thickness(P<0.05),but it did not affect growth performance.TMAO significantly increased total protein(TP)concentration,and reduced alkaline phosphatase(ALP)concentration in serum(P<0.05).TMAO increased the α diversity of the ileal microbiota community(P<0.05),and it did not affect the colonic microbial community.TMAO supplementation significantly increased acetate content in the ileum,and Proteobacteria and Escherichia-Shigella were significantly enriched in the TMAO group(P<0.05).In addition,TMAO decreased fat content,as well as the ratio of linoleic acid,n-6 polyunsaturated fatty acids(PUFA),and PUFA in the liver(P<0.05).On the contrary,TMAO increased intramuscular fat content of the longissimus dorsi muscle,whereas the C18:2n6c ratio was increased,and the n-6 PUFA:PUFA ratio was decreased(P<0.05).In vitro,1 mmol/LTMAO treatment significantly upregulated the expression of FASN and SREBP1 in C2C12 cells(P<0.05).Nevertheless,TMAO also increased adipocyte area and decreased the CPT-1B expression in subcutaneous fat(P<0.05).Taken together,TMAO supplementation regulated ileal microbial composition and acetate production,and regulated fat distribution and fatty acid composition in growing-finishing pigs.These results provide new insights for understanding the role of TMAO in humans and animals.

单双段回肠Yang-Monti管术膀胱可控性流出道在尿道损毁患者中应用的对比研究

目的探讨Yang-Monti管术膀胱可控性流出道治疗尿道损毁患者的有效性和安全性,比较单段与双段回肠管的应用效果。方法回顾性分析四川大学华西医院2009年1月至2018年2月收治的27例行Yang-Monti管术患者的临床资料,其中采用单段回肠14例(单段组),双段回肠13例(双段组)。单段组和双段组的年龄分别为(56.5±4.3)岁和(50.2±6.8)岁(P=0.220),男/女分别为2/12例和3/10例(P=0.564),体质指数分别为(19.6±1.3)kg/m^(2)和(24.2±2.1)kg/m^(2)(P<0.001),病程分别为6(3~24)个月和8(3~48)个月(P=0.650),术前生活质量(QOL)评分分别为(46.7±1.7)分和(45.5±1.7)分(P=0.061),术前发生尿路感染例数分别11例和13例(P=0.480)。单段组2例伴高血压病。单段组距回盲部约15 cm处截取2 cm带系膜血管的回肠,沿对系膜缘肠管走行方向纵行切开,将肠片横行包绕F12尿管并用3-0单乔线间断缝合卷成Yang-Monti管。于膀胱顶壁偏前外侧切开膀胱壁长约1 cm,将Yang-Monti管与膀胱壁黏膜肌层端端吻合。于髂前上棘水平腹直肌处做直径约1 cm圆形切口,用弯钳穿刺入腹形成隧道,将Yang-Monti管沿隧道引出腹壁,管口与皮下缝合固定,同时于腹腔内将管壁用4-0丝线固定于腹膜。双段组截取2段2.0 cm回肠,沿对系膜缘肠管走行方向纵行切开肠管后,先将肠片端端缝合后再卷管重建,形成直径0.6~0.8 cm、长径约12.0 cm的Yang-Monti管,将Yang-Monti管近端与膀胱黏膜肌层直接间断吻合。比较两组的手术时间、术中出血量、术后导尿间隔、术后单次导尿量、术后并发症(出血、肠梗阻、吻合口瘘、吻合口狭窄、造口感染、尿路感染)和QOL评分等。结果两组手术均顺利完成。单段组和双段组的手术时间分别为(165.8±17.8)min和(157.54±12.25)min(P=0.302),术中出血量分别为(60.0±20.0)ml和(50.0±25.0)ml(P=0.650),术后恢复进食时间分别为3(2~4)d和3(2~9)d(P=0.790),术后住院时间分别为12(9~40)d和12(10~32)d(P=0.259),术后单次导尿量分别为(240.4±42.7)ml和(261.5±36.3)ml(P=0.186),术后QOL评分分别为(22.4±2.7)分和(21.5±2.6)分(P=0.325),差异均无统计学意义。单段组术后2例发生尿路感染,双段组发生尿路感染、术后出血、肠梗阻各1例,两组比较差异无统计学意义(P=0.222)。单段组和双段组术后导尿间隔分别为(2.5±1.0)h和(3.5±1.3)h,差异有统计学意义(P=0.029)。两组的术后生活质量评分(P<0.001)和术后尿路感染发生率(P=0.011)与术前相比差异均有统计学意义。结论单段和双段回肠Yang-Monti管术对于尿道毁损患者均是可行的手术方式,两种手术效果没有差异,均能改善患者生活质量,并发症发生率低。

钬激光剜除术和绿激光选择性汽化术治疗良性前列腺增生有效性及安全性的Meta分析

目的:比较钬激光前列腺剜除术(HoLEP)和绿激光选择性前列腺汽化术(PVP)治疗良性前列腺增生(BPH)的安全性和有效性。方法:检索PubMed、EMBASE、Cochrane library、CKNI、万方数据库,筛选符合要求的HoLEP和PVP的对照研究,并对文献进行质量评价和资料提取,最后应用统计软件RevMan 5.3完成M eta分析。结果:最终纳入5篇文献,总样本量为1 094例。Meta分析结果显示:在激光使用总能量上,HoLEP组明显少于PVP组,差异有统计学意义[-72.67,95%CI(-109.69,-35.65),P<0.01]。HoLEP组术后国际前列腺症状评分(IPSS)评分优于PVP组[-2.02,95%CI(-3.67,-0.36),P<0.05],HoLEP组术后最大尿流率(Q_(max))明显高于PVP组,差异有统计学意义[5.74,95%CI(2.23,9.25),P<0.01]。两组患者在手术时间和导尿管留置时间,术后生活质量评分(QOL)、残余尿量(PVR)、前列腺特异性抗原(PSA)、前列腺体积及部分术后并发症发生率方面差异均无统计学意义(P>0.05)。结论:HoLEP与PVP在改善患者QOL评分、PVR、PSA、前列腺体积方面有相似的临床疗效,然而HoLEP组激光所用总能量明显更少,术后IPSS明显降低,Q_(max)明显增加,更具优势。因此,HoLEP有望成为更适用于治疗BPH的激光手术方式。

2型糖尿病肾病患者血清GDF-15、sVCAM-1、YKL-40、α-klotho蛋白水平与糖脂代谢、胰岛素抵抗及肾功能的相关性分析

目的:探讨2型糖尿病(T2DM)肾病患者血清可溶性血管细胞黏附分子-1(s VCAM-1)、生长分化因子-15(GDF-15)、α-klotho蛋白、几丁质酶3样蛋白1(YKL-40)水平与糖脂代谢、胰岛素抵抗及肾功能的关系。方法:选取2017年2月2020年5月期间我院收治的T2DM患者80例,将T2DM患者根据有无糖尿病肾病分为T2DM无肾病组(n=43)、T2DM肾病组(n=37)。并选取同期于我院体检的健康志愿者50例作为对照组。检测所有受试者的血脂指标:总胆固醇(TC)、高密度脂蛋白(HDL)、甘油三酯(TG)、低密度脂蛋白(LDL),肾功能指标:尿素氮(BUN)、肌酐(Scr),血糖指标:糖化血红蛋白(HbA1c)、空腹血糖(FPG),胰岛素抵抗指标:稳态模型-胰岛素抵抗指数(HOMA-IR),GDF-15、s VCAM-1、α-klotho蛋白、YKL-40水平。分析血清GDF-15、s VCAM-1、YKL-40、α-klotho蛋白水平与血糖指标、血脂指标、胰岛素抵抗指标、肾功能指标的相关性。结果:T2DM肾病组GDF-15、s VCAM-1、YKL-40较对照组、T2DM无肾病组高(P<0.05),T2DM肾病组α-klotho蛋白低于T2DM无肾病组、对照组(P<0.05)。T2DM肾病组、T2DM无肾病组TC、TG、LDL、BUN、HOMA-IR、Scr、FPG、HbA1c水平较对照组高,且T2DM肾病组高于T2DM无肾病组(P<0.05),T2DM肾病组、T2DM无肾病组HDL水平低于对照组,且T2DM肾病组低于T2DM无肾病组(P<0.05)。Pearson相关性分析结果显示,GDF-15、sVCAM-1、YKL-40与TC、TG、LDL、BUN、Scr、FPG、HbA1c、HOMA-IR均呈正相关,而与HDL呈负相关(P<0.05),α-klotho蛋白与TC、TG、LDL、BUN、Scr、FPG、HbA1c、HOMA-IR均呈负相关,而与HDL呈正相关(P<0.05)。结论:GDF-15、sVCAM-1、YKL-40、α-klotho蛋白在T2DM肾病患者血清中异常表达,可能参与该疾病的发生、发展。

原位新膀胱的尿流动力学评估及改善尿控功能的重建技术

根治性膀胱全切术联合原位新膀胱是浸润性膀胱癌患者的最佳治疗选择。目前新膀胱术后功能评价标准尚不完善。尿流动力学检查作为评估膀胱功能的客观手段,在临床上应用广泛。完善标准化尿流动力学检查可对术后新膀胱的功能进行持续监测以指导管理,从而提高术后生活质量。理想的原位新膀胱应有适宜尿流率、足够的容量、残余尿少、低压、高顺应性、稳定、具有良好的排尿和控尿能力。针对保护排尿及控尿机制的重建技术,对于解决原位新膀胱术后新膀胱功能障碍至关重要。本文基于尿流动力学对原位新膀胱功能评价内容进行综述,并对促进尿控功能的重建技术加以总结,为临床治疗及术后功能评价提供参考。

腹腔镜与开放输尿管膀胱再植术治疗输尿管阴道瘘的临床效果对比分析

目的:对比我院既往腹腔镜下与开放手术行输尿管再植术治疗输尿管阴道瘘的处理情况及患者结局,进而分析并总结腹腔镜下输尿管再植术的临床效果。方法:回顾性分析了2008年—2018在四川大学华西医院就诊的80例患者资料,依据手术方式分为开放组(60例)和腹腔镜组(20例),比较了两组在住院时间、手术结局及并发症等方面的差异。结果:开放组同腹腔镜组在手术结局(58/60 vs.19/20,P=1),术后并发症(伤口感染:3.33%vs.0,P=1;切口疼痛:11.67%vs.0,P=0.25;慢性尿路感染:5.00%vs.0,P=0.57)等方面差异无统计学意义,住院时间腹腔镜组显著短于开放组(8 d vs.6 d,P<0.001)。结论:对于输尿管阴道瘘这一损伤,腹腔镜下输尿管再植术具有住院时间短、恢复快等优点,且疗效确切,未增加并发症的发生率,值得临床推广。