Introduction Liver cirrhosis generally occurs with the hemodynamic changes during the portal vein hypertension and finally leads to the atrophy of the right lobe of the liver and hepatic failure<sup>[1]</sup&...Introduction Liver cirrhosis generally occurs with the hemodynamic changes during the portal vein hypertension and finally leads to the atrophy of the right lobe of the liver and hepatic failure<sup>[1]</sup>.According to the hemodynamic changes,a hypothesis has been proposed that the liver volume is related to the istribution of blood from the splenic vein（SV）that involves nutrition from spleen and pancreas<sup>[2,3]</sup>.The objective of the present paper is to simulate the blood flow in real models of portal vein hypertension and validate the hypothesis using computational fluid dynamics（CFD）method.Methods This study includes 2 patients with liver cirrhosis and a set of 4 normal subjects.展开更多
What is already known about this topic?Addressing health disparities is a worldwide priority,with a well-established acknowledgment of the influence of childhood circumstances on these discrepancies.In China,particula...What is already known about this topic?Addressing health disparities is a worldwide priority,with a well-established acknowledgment of the influence of childhood circumstances on these discrepancies.In China,particularly among the elderly,health inequalities are a notable concern.What is added by this report?The inequality in healthy aging has increased from 2011 to 2020,both in general and concerning childhood factors.Nevertheless,the impact of early-life healthcare access and parental health behaviors on healthy aging gaps has reduced among older adults in better health within the top segment of healthy aging.What are the implications for public health practice?Efforts towards reducing regional health disparities and improving healthcare access for children,along with promoting the health and well-being of parents,especially in economically disadvantaged households,are crucial policy considerations.展开更多
基金supported by National Science Foundation of China(51176152)Specialized Research Fund for the Doctoral Program of Higher Education(20120201110070)the Fundamental Research Funds for the Central University(xjj2012115)
文摘Introduction Liver cirrhosis generally occurs with the hemodynamic changes during the portal vein hypertension and finally leads to the atrophy of the right lobe of the liver and hepatic failure<sup>[1]</sup>.According to the hemodynamic changes,a hypothesis has been proposed that the liver volume is related to the istribution of blood from the splenic vein（SV）that involves nutrition from spleen and pancreas<sup>[2,3]</sup>.The objective of the present paper is to simulate the blood flow in real models of portal vein hypertension and validate the hypothesis using computational fluid dynamics（CFD）method.Methods This study includes 2 patients with liver cirrhosis and a set of 4 normal subjects.
基金supported by the National Natural Sciences Foundation of China(grant numbers 71804142 and 72074178)the Start-up Fund for Young Talent Support Plan(grant number 11304222010701)。
文摘What is already known about this topic?Addressing health disparities is a worldwide priority,with a well-established acknowledgment of the influence of childhood circumstances on these discrepancies.In China,particularly among the elderly,health inequalities are a notable concern.What is added by this report?The inequality in healthy aging has increased from 2011 to 2020,both in general and concerning childhood factors.Nevertheless,the impact of early-life healthcare access and parental health behaviors on healthy aging gaps has reduced among older adults in better health within the top segment of healthy aging.What are the implications for public health practice?Efforts towards reducing regional health disparities and improving healthcare access for children,along with promoting the health and well-being of parents,especially in economically disadvantaged households,are crucial policy considerations.
