Nitrogen-containing compounds are ubiquitously found in the fields of organic chemistry,pharmaceuticals,agrochemicals,medicinal chemistry and functional materials.The C-H bond amination reaction is one of the most str...Nitrogen-containing compounds are ubiquitously found in the fields of organic chemistry,pharmaceuticals,agrochemicals,medicinal chemistry and functional materials.The C-H bond amination reaction is one of the most straightforward protocols in the CN bond formation,showing"step"and"atomic"economy.As a catalyst for C-H amination reaction,copper exhibits its unique catalytic properties due to easily accessible oxidation states.The research progress of copper-catalyzed C-H amination in recent years is summarized.At the same time,reaction mechanisms are also briefly described in representative aminations to provide insights for the development prospects of highly practical and more environmentally benignprocesses.展开更多
基金We are grateful for financial support from the National Natural Science Foundation of China(Nos.21938001,21961160741,22078072)the Special Innovation Project of Guangdong Provincial Department of Education(No.2021KTSCX082)+2 种基金the Science and Technology Plan Project of Maoming City(Nos.2020581,2021009,2021012)the Guangdong Basic and Applied Basic Research Foundation(No.2019A1515110346)the Scientific Research Foundation of Guangdong University of Petrochemical Technology(Nos.517152,2019rc053).
文摘Nitrogen-containing compounds are ubiquitously found in the fields of organic chemistry,pharmaceuticals,agrochemicals,medicinal chemistry and functional materials.The C-H bond amination reaction is one of the most straightforward protocols in the CN bond formation,showing"step"and"atomic"economy.As a catalyst for C-H amination reaction,copper exhibits its unique catalytic properties due to easily accessible oxidation states.The research progress of copper-catalyzed C-H amination in recent years is summarized.At the same time,reaction mechanisms are also briefly described in representative aminations to provide insights for the development prospects of highly practical and more environmentally benignprocesses.
