Dielectric optical antennas have emerged as a promising nanophotonic architecture for manipulating the propagation and localization of light.However,the optically induced Mie resonances in an isolated nanoantenna are ...Dielectric optical antennas have emerged as a promising nanophotonic architecture for manipulating the propagation and localization of light.However,the optically induced Mie resonances in an isolated nanoantenna are normally with broad spectra and poor𝑄-factors,limiting their performances in sensing,lasing,and nonlinear optics.Here,we dramatically enhance the𝑄-factors of Mie resonances in silicon(Si)nanoparticles across the optical band by arranging the nanoparticles in a periodic lattice.We select monocrystalline Si with negligible material losses and develop a unique method to fabricate nanoparticle arrays on a quartz substrate.By extinction dispersion measurements and electromagnetic analysis,we can identify three types of collective Mie resonances with𝑄-factors∼500 in the same nanocylinder arrays,including surface lattice resonances,bound states in the continuum,and quasi-guided modes.Our work paves the way for fundamental research in strong light-matter interactions and the design of highly efficient light-emitting metasurfaces.展开更多
In present investigation, we constructed recombinants expressing the HCV genotypes 1b, 2a, and 4d core proteins, and established human hepatocellular carcinoma （HepG2） cell line that expressed various genotype core ...In present investigation, we constructed recombinants expressing the HCV genotypes 1b, 2a, and 4d core proteins, and established human hepatocellular carcinoma （HepG2） cell line that expressed various genotype core proteins. The gene expression profiles in the cells expressing different HCV genotype core proteins were compared with those in the control by microarray analysis. In data analysis, a threshold was set to eliminate all genes that were not increased or decreased by 2.5-fold change in a comparison between the transfected cells and control cells. The preliminary microarray analysis suggests that the gene expression profiles regulated by three kinds of genotype core proteins are mainly involved in transport, signal transduction, regulation of transcription, protease activity, etc., and that some pathogenesis/oncogenesis gene expressions are up/down- regulated simultaneously in the HepG2 cell line. The data suggest that each core protein has its gene expressions profile and that the profiles are implicated in HCV replication and pathogenesis, which may open up a novel way to understand the function of the HCV variant core proteins biological and their pathogenic mechanism. Cellular ＆ Molecular Immunology. 2006;3（3）：227-233.展开更多
Main observation and conclusion Aqueous heterogeneous catalysis is a green,sustainable catalytic process that attracts increasing attention,but it often suffers from poor mass transfer,substrate adsorption and catalys...Main observation and conclusion Aqueous heterogeneous catalysis is a green,sustainable catalytic process that attracts increasing attention,but it often suffers from poor mass transfer,substrate adsorption and catalyst dispersion.Herein,we synthesized a type of amphiphilic core-shell catalysts with a hydrophilic polydopamine(PDA)shell and a hydrophobic dendritic organosilica nanoparticle(DON)core for heterogeneous catalysis in water.展开更多
基金the National Natural Science Foundation of China(62120106001,62275184,61875143,and 62104165)the Natural Science Foundation of Jiangsu Province(BK20200859,BK20200857,and BK20210713)the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions.JGR and PB also acknowledge financial support from Nederlandse Organisatie voor Wetenschappelijk Onderzoek(NWO)(Vici 680-47-628).
文摘Dielectric optical antennas have emerged as a promising nanophotonic architecture for manipulating the propagation and localization of light.However,the optically induced Mie resonances in an isolated nanoantenna are normally with broad spectra and poor𝑄-factors,limiting their performances in sensing,lasing,and nonlinear optics.Here,we dramatically enhance the𝑄-factors of Mie resonances in silicon(Si)nanoparticles across the optical band by arranging the nanoparticles in a periodic lattice.We select monocrystalline Si with negligible material losses and develop a unique method to fabricate nanoparticle arrays on a quartz substrate.By extinction dispersion measurements and electromagnetic analysis,we can identify three types of collective Mie resonances with𝑄-factors∼500 in the same nanocylinder arrays,including surface lattice resonances,bound states in the continuum,and quasi-guided modes.Our work paves the way for fundamental research in strong light-matter interactions and the design of highly efficient light-emitting metasurfaces.
文摘In present investigation, we constructed recombinants expressing the HCV genotypes 1b, 2a, and 4d core proteins, and established human hepatocellular carcinoma （HepG2） cell line that expressed various genotype core proteins. The gene expression profiles in the cells expressing different HCV genotype core proteins were compared with those in the control by microarray analysis. In data analysis, a threshold was set to eliminate all genes that were not increased or decreased by 2.5-fold change in a comparison between the transfected cells and control cells. The preliminary microarray analysis suggests that the gene expression profiles regulated by three kinds of genotype core proteins are mainly involved in transport, signal transduction, regulation of transcription, protease activity, etc., and that some pathogenesis/oncogenesis gene expressions are up/down- regulated simultaneously in the HepG2 cell line. The data suggest that each core protein has its gene expressions profile and that the profiles are implicated in HCV replication and pathogenesis, which may open up a novel way to understand the function of the HCV variant core proteins biological and their pathogenic mechanism. Cellular ＆ Molecular Immunology. 2006;3（3）：227-233.
基金This work was financially supported by the National Natural Science Foundation of China(Nos.21901058,21908040 and 22078081)the Science and Technology Research Project of Hebei Higher Education(ZD2019045)+2 种基金the Natural Science Foundation of Hebei province(B2017202056 and B2019202216)the Natural Science Foundation of Tianjin City(20JCYBJC00530)the Foundation of Tianjin Key Laboratory of Brine Chemical Engineering and Resource Eco-utilization(Tianjin University of Science and Technology),People's Republic of China(BCERE202001).
文摘Main observation and conclusion Aqueous heterogeneous catalysis is a green,sustainable catalytic process that attracts increasing attention,but it often suffers from poor mass transfer,substrate adsorption and catalyst dispersion.Herein,we synthesized a type of amphiphilic core-shell catalysts with a hydrophilic polydopamine(PDA)shell and a hydrophobic dendritic organosilica nanoparticle(DON)core for heterogeneous catalysis in water.
