It is well-documented that male overweight and obesity causes endocrine disorders that might diminish the male reproductive capacity; however, reports have been conflicting regarding the influence of male body mass in...It is well-documented that male overweight and obesity causes endocrine disorders that might diminish the male reproductive capacity; however, reports have been conflicting regarding the influence of male body mass index （BMI） on semen quality and the outcome of assisted reproductive technology （ART）. The aim of this study was to investigate whether increased male BMI affects sperm quality and the outcome of assisted reproduction in couples with an overweight or obese man and a non-obese partner. Data was prospectively collected from 612 infertile couples undergoing ART at a Danish fertility center. Self-reported information on paternal height and weight were recorded and BMI was calculated. The men were divided into four BMI categories： underweight BMI 〈 20 kgm^-2, normal BMI 20-24.9 kg m^-2, overweight BMI 25-29.9 kgm^-2 and obese BMI 〉 30 kgm^-2. Conventional semen analysis was performed according to the World Health Organization guideline and sperm DNA integrity was analyzed by the Sperm Chromatin Structure Assay （SCSA）. No statistically significant effect of male BMI was seen on conventional semen parameters （sperm concentration, total sperm count, seminal volume and motility） or on SCSA-results. Furthermore, the outcome of ART regarding fertilization rate, number of good quality embryos （GQE）, implantation and pregnancy outcome was not influenced by the increasing male BMIo展开更多
Dear Editor,During the last decade,there has been an increase in the usage of dietary protein supplements for bodybuilding,especially among young men who work out in commercial gyms.1 Recently,it was shown that 23 of ...Dear Editor,During the last decade,there has been an increase in the usage of dietary protein supplements for bodybuilding,especially among young men who work out in commercial gyms.1 Recently,it was shown that 23 of 24 dietary supplements available in fitness equipment and online shops contained anabolic steroids.2 However,these supposedly pro-androgenic supplements presumably differ from the more commonly used whey and soy protein supplements.3,4 Notwithstanding,both products are listed as dietary supplements rather than medical drugs;thus,they are not rigorously tested,5 do not necessarily list all contents,2 and consequently might contain known and unknown active components3,6.展开更多
文摘It is well-documented that male overweight and obesity causes endocrine disorders that might diminish the male reproductive capacity; however, reports have been conflicting regarding the influence of male body mass index （BMI） on semen quality and the outcome of assisted reproductive technology （ART）. The aim of this study was to investigate whether increased male BMI affects sperm quality and the outcome of assisted reproduction in couples with an overweight or obese man and a non-obese partner. Data was prospectively collected from 612 infertile couples undergoing ART at a Danish fertility center. Self-reported information on paternal height and weight were recorded and BMI was calculated. The men were divided into four BMI categories： underweight BMI 〈 20 kgm^-2, normal BMI 20-24.9 kg m^-2, overweight BMI 25-29.9 kgm^-2 and obese BMI 〉 30 kgm^-2. Conventional semen analysis was performed according to the World Health Organization guideline and sperm DNA integrity was analyzed by the Sperm Chromatin Structure Assay （SCSA）. No statistically significant effect of male BMI was seen on conventional semen parameters （sperm concentration, total sperm count, seminal volume and motility） or on SCSA-results. Furthermore, the outcome of ART regarding fertilization rate, number of good quality embryos （GQE）, implantation and pregnancy outcome was not influenced by the increasing male BMIo
文摘Dear Editor,During the last decade,there has been an increase in the usage of dietary protein supplements for bodybuilding,especially among young men who work out in commercial gyms.1 Recently,it was shown that 23 of 24 dietary supplements available in fitness equipment and online shops contained anabolic steroids.2 However,these supposedly pro-androgenic supplements presumably differ from the more commonly used whey and soy protein supplements.3,4 Notwithstanding,both products are listed as dietary supplements rather than medical drugs;thus,they are not rigorously tested,5 do not necessarily list all contents,2 and consequently might contain known and unknown active components3,6.
