The objective of this study was to determine the integrity of the homoeostatic coupling relationship between neuronal electrical function and cerebral metabol ism in the vegetative and minimally conscious states. Ten ...The objective of this study was to determine the integrity of the homoeostatic coupling relationship between neuronal electrical function and cerebral metabol ism in the vegetative and minimally conscious states. Ten patients who met recog nised diagnostic criteria (six in the vegetative state and four minimally consci ous) were investigated using simultaneous electroencephalography and positron em ission tomography. It was found that the coupling between neuronal electrical ac tivity and regional glucose metabolism was preserved in all the minimally consci ous patients but was absent in all the vegetative state patients. Our preliminar y results suggest patients in the vegetative state may endure an impaired coupli ng relation between neuronal electrical function and cerebral energy metabolism.展开更多
文摘The objective of this study was to determine the integrity of the homoeostatic coupling relationship between neuronal electrical function and cerebral metabol ism in the vegetative and minimally conscious states. Ten patients who met recog nised diagnostic criteria (six in the vegetative state and four minimally consci ous) were investigated using simultaneous electroencephalography and positron em ission tomography. It was found that the coupling between neuronal electrical ac tivity and regional glucose metabolism was preserved in all the minimally consci ous patients but was absent in all the vegetative state patients. Our preliminar y results suggest patients in the vegetative state may endure an impaired coupli ng relation between neuronal electrical function and cerebral energy metabolism.
