Stroke is a common neurological condition and among the leading causes of death and disability worldwide.Depression is both a risk factor for and complication of stroke,and the two conditions may have a complex recipr...Stroke is a common neurological condition and among the leading causes of death and disability worldwide.Depression is both a risk factor for and complication of stroke,and the two conditions may have a complex reciprocal relationship over time.However,the secondary effects of depression on stroke are often overlooked,resulting in increased morbidity and mortality.In the previous concept of‘poststroke depression’,stroke and depression were considered as two independent diseases.It often delays the diagnosis and treatment of patients.The concept‘stroke depression’proposed in this article will emphasise more the necessity of aggressive treatment of depression in the overall management of stroke,thus to reduce the incidence of stroke and in the meantime,improve the prognosis of stroke.Hopefully,it will lead us into a new era of acute stroke intervention.展开更多
基金supported by grants from the National Key R&D Program of China(Grant No.2017YFA0505700)the Non-Profit Central Research Institute Fund of the Chinese Academy of Medical Sciences(Grant No.2019PT320002)the Natural Science Foundation Project of China(Grant No.81820108015).
文摘Stroke is a common neurological condition and among the leading causes of death and disability worldwide.Depression is both a risk factor for and complication of stroke,and the two conditions may have a complex reciprocal relationship over time.However,the secondary effects of depression on stroke are often overlooked,resulting in increased morbidity and mortality.In the previous concept of‘poststroke depression’,stroke and depression were considered as two independent diseases.It often delays the diagnosis and treatment of patients.The concept‘stroke depression’proposed in this article will emphasise more the necessity of aggressive treatment of depression in the overall management of stroke,thus to reduce the incidence of stroke and in the meantime,improve the prognosis of stroke.Hopefully,it will lead us into a new era of acute stroke intervention.