Design and prototyping of the readout electronics for the transition radiation detector in the high energy cosmic radiation detection facility

The high energy cosmic-radiation detection(HERD)facility is planned to launch in 2027 and scheduled to be installed on the China Space Station.It serves as a dark matter particle detector,a cosmic ray instrument,and an observatory for high-energy gamma rays.A transition radiation detector placed on one of its lateral sides serves dual purpose,(ⅰ)calibrating HERD's electromagnetic calorimeter in the TeV energy range,and(ⅱ)serving as an independent detector for high-energy gamma rays.In this paper,the prototype readout electronics design of the transition radiation detector is demonstrated,which aims to accurately measure the charge of the anodes using the SAMPA application specific integrated circuit chip.The electronic performance of the prototype system is evaluated in terms of noise,linearity,and resolution.Through the presented design,each electronic channel can achieve a dynamic range of 0–100 fC,the RMS noise level not exceeding 0.15 fC,and the integral nonlinearity was<0.2%.To further verify the readout electronic performance,a joint test with the detector was carried out,and the results show that the prototype system can satisfy the requirements of the detector's scientific goals.

中医治未病领域中免疫组库(TCR/BCR)作为一种新型“全息”生物标志物的应用与展望

中医“治未病”理论构成了中医药健康管理的主要内容,“治未病”思想为中医药健康管理体系赋予科学内涵,中医药健康管理体系也是“治未病”思想的外在体现,该体系的建立与完善离不开中医“治未病”思想的深度解析。“治未病”思想的深度解析需要从科学意义上深度思考三个关键问题:一是如何客观描述“未病”的生物学基础并阐明“未病”发生机制;二是如何阐释中医“治未病”科学内涵及中药复方的特殊药理效应机制;三是如何构建以中医“治未病”为内核的中医药精准健康管理新模式。本文从监管科学角度出发,首次提出“全息”生物标志物免疫组库(TCR/BCR)可作为新型“全息”生物标志物,用以客观表征中医治未病生物学基础和干预效果的科学评价体系,进而作为新的科学证据解释上述三个关键科学问题。

Does Green Food Certification promote agri-food export quality?Evidence from China

The construction of a food certification system plays a vital role in upgrading export quality, which previous studies have largely overlooked. We match China's industry-level data of Green Food Certification with its HS6-digit export data of agri-food products to quantify the impact of Green Food Certification on export quality. We identify the significant and positive effect of Green Food Certification on export quality. The 2SLS estimation based on instrumental variables and a range of robustness checks confirm the validity and robustness of the benchmark conclusions. Further analysis discloses that Green Food Certification improves export quality by raising agricultural production efficiency and brand premiums. Heterogeneity analysis shows that the effect of Green Food Certification varies across regions, notably improving the quality of agri-food products exported to developed regions and regions with high levels of import supervision. Furthermore, among various product types, Green Food Certification significantly improves the export quality of primary products and products vulnerable to non-tariff measures. The above findings could guide the future development of agri-food quality certification systems, potentially leading to a transformation and promotion of the agri-food trade.

多气源上载天然气管道工况运行适应性分析

天然气管道输送过程中,气源上载点的增加必然引起运行工况的变化。如果在缺乏科学依据的情况下,盲目进行管道新工况输送,易出现气源分配不合理或无法完成指定输量输送,管道工况运行不适应。以某ZG天然气管道为研究对象,利用SPS软件模拟分析管线气源上载增加后,分析管道正输工况的运行适应性。研究结果表明,ZG天然气管道存在运行不适应的工况,需采取调整气源输送压力、分配输量以及增启压气站等方式,提高管道运行适应性,实现多气源上载管道安全运行具有重要意义。

Focus on laboratory tests related to the pathological types of lupus nephritis to implement renal biopsy as early as possible:clinical and pathological analysis of 217 cases of single center lupus nephritis

Objective:To analyze the clinical and laboratory indices of patients with lupus nephritis(LN)of different pathological types and explore the related factors of LN pathological classification,it is helpful to grasp the timing of renal biopsy.Methods:The clinical manifestations,laboratory parameters and renal pathological types of LN patients in recent 20 years were analyzed retrospectively by SPSS 26.0 software.Results:In this study,the first three pathological types were V,IV,V+IV;latent nephritis was common in type II and V;nephritic syndrome was common in type V;nephrotic syndrome was common in type V+IV;chronic renal insufficiency group was mostly type IV;pathological types were correlated with serum creatinine,C3,albumin and erythrocyte sedimentation rate(r=0.315,P<0.001),and serum creatinine was moderately correlated(r=0.315,P<0.001);AI,CI and SLEDAI scores were significantly different among LN patients of different pathological types.Conclusion:LN is closely related to clinical pathology,clinical manifestations,comprehensive analysis of laboratory indicators and SLEDAI score to make a preliminary prediction of LN pathological type,help to initially assess the severity of pathology,improve the timing of renal biopsy implementation,optimize the timing of treatment.

温针灸联合贺氏火针及消瘤汤治疗子宫肌瘤的临床疗效观察

目的 探究在子宫肌瘤患者治疗中应用温针灸联合贺氏火针以及消瘤汤的临床效果。方法 102例子宫肌瘤患者,按入院顺序进行编号,根据编号奇偶数分为对照组(奇数)和观察组(偶数),每组51例。对照组采用消瘤汤进行治疗,观察组在对照组基础上联合温针灸以及贺氏火针进行治疗。比较两组的临床治疗效果及治疗前后中医证候积分、雌激素[血清促卵泡生成素(FSH)、促黄体生成素(LH)、雌二醇(E_(2))]水平、生活质量评分。结果 观察组患者治疗总有效率为96.08%,高于对照组的80.39%,差异具有统计学意义(P<0.05)。治疗3个月后,两组患者中医证候积分均低于本组治疗前,且观察组患者中医证候积分(11.87±2.65)分低于对照组的(19.22±3.35)分,差异具有统计学意义(P<0.05)。治疗3个月后,观察组患者血清FSH、LH、E_(2)水平分别为(8.39±2.83)IU/L、(7.67±1.68)IU/L、(145.15±28.05)pmol/L,均低于对照组的(15.63±3.18)IU/L、(13.82±2.30)IU/L、(239.33±19.75)pmol/L,差异具有统计学意义(P<0.05)。治疗3个月后,观察组患者躯体功能、角色功能、社会功能评分分别为(88.40±2.32)、(88.43±3.81)、(88.90±3.46)分,高于对照组的(76.52±2.28)、(76.19±3.62)、(77.01±3.30)分,差异具有统计学意义(P<0.05)。结论 温针灸联合贺氏火针以及消瘤汤治疗子宫肌瘤患者可以获得理想的治疗效果,不仅可以缓解患者的各项临床症状,而且可以改善雌激素水平,提高生活质量,促进患者康复,值得大力在临床上进行推广。

Advances on genetic and genomic studies of ALV resistance

Avian leukosis(AL)is a general term for a variety of neoplastic diseases in avian caused by avian leukosis virus(ALV).No vaccine or drug is currently available for the disease.Therefore,the disease can result in severe economic losses in poultry flocks.Increasing the resistance of poultry to ALV may be one effective strategy.In this review,we provide an overview of the roles of genes associated with ALV infection in the poultry genome,including endogenous retroviruses,virus receptors,interferon-stimulated genes,and other immune-related genes.Furthermore,some methods and techniques that can improve ALV resistance in poultry are discussed.The objectives are willing to provide some valuable references for disease resistance breeding in poultry.

Analysis on the spatial pattern and evolution of China's petroleum trade under the dual effect of international oil price and “Belt and Road” Framework

“Belt and Road” is the important origin of oil import in China. Based on social network analysis and stochastic frontier gravity model, this paper studied the characteristic evolution and influence factor of oil import network between China and “Belt and Road” countries. Then by constructing a stochastic frontier gravity model including the crude oil future price and oil importing price, it found that the international crude oil future price, the oil importing price, the political situation, the trade agreements have the effects on the China's oil import from “Belt and Road” region. It provided suggestions for improving the spatial pattern of China's petroleum trade.

氨甲环酸联合阿司匹林对老年人工全膝关节置换术围术期出血量、膝关节功能恢复及内皮功能的影响

目的探讨氨甲环酸联合阿司匹林对老年人工全膝关节置换术(TKA)围术期出血量、膝关节功能恢复及内皮功能的影响。方法选取2016年1月—2018年1月我院收治的行TKA的老年患者170例为研究对象,按治疗方法不同分为观察组和对照组,每组85例。观察组给予TKA术中关节腔内注射氨甲环酸+口服阿司匹林;对照组给予TKA术中注射0.9%氯化钠注射液+皮下注射低分子肝素,评估2组失血量(术后24 h引流袋内引流量、总失血量、隐性失血量。于手术前、术后72 h测定并比较2组血红蛋白(Hb)、C反应蛋白(CRP)及血管内皮损伤相关因子[可溶性血栓调节蛋白(sTM)、E-选择素及血管内皮生长因子(VEGF)]水平;术中及术后3 h测定凝血指标[纤维蛋白原(FIB)、凝血酶原时间(PT)及活化部分凝血活酶时间(APTT)]水平,评估2组膝关节功能恢复及并发症发生情况。结果观察组总失血量、隐性失血量及术后24 h引流管引流量均低于对照组(P<0.05)。2组手术后美国特种外科膝关节评分均高于手术前,且观察组高于对照组(P<0.05)。与治疗前相比,2组术后72 h的Hb、sTM、E-选择素、VEGF水平下降,CRP明显上升,且观察组上述指标优于对照组,差异有统计学意义(P<0.05)。2组患者术中及术后3 h的FIB、PT、APTT水平比较差异均无统计学意义(P>0.05)。观察组并发症总发生率明显低于对照组(P<0.05)。结论对老年TKA患者给予氨甲环酸联合阿司匹林可有效减少围术期出血量,同时可对老年患者的内皮功能进行保护,减少炎症内皮损伤。

生物质改性吸附材料的制备工艺优化及对氨氮的吸附特性

为探究农业生物质再利用方法,以香蕉皮为原料,通过化学改性制备改性吸附剂,去除水中的氨氮。通过对比实验选择Na OH作为改性剂对香蕉皮粉末进行改性,单因素实验探讨了改性剂浓度、改性时间、原材料粒径及固液比对制备过程的影响及最佳制备工艺参数,结果表明:香蕉皮粉末粒径为100~120目,以0.2 mol·L^(-1)的Na OH水溶液作为改性剂,以10 g·L^(-1)的固液比,对香蕉皮粉末改性20 min为最佳的制备条件,在此条件下制得的改性吸附剂产率为64.83%。扫描电镜(SEM)、傅里叶变换红外光谱(FT-IR)、BET法测定比表面积及孔径分析结果显示,材料经改性后,表面孔道结构和官能团的变化有利于吸附氨氮。利用制得的材料吸附不同浓度的氨氮废水,并对实验结果进行等温拟合分析,Langmuir拟合结果表明改性香蕉皮吸附剂对水中的氨氮具有较高的吸附容量(qm=16.051 mg·g-1),优于沸石和活性炭,Freundlich拟合结果表明材料吸附氨氮属于较易发生的吸附(1/n=0.681)。研究表明,改性香蕉皮对氨氮具有较高的吸附容量,优于沸石和活性炭,对氨氮的吸附较易发生。

氨甲环酸在全膝关节置换术围术期的应用效果分析

目的分析氨甲环酸在全膝关节置换术围术期的应用效果。方法以2018年12月至2020年3月本院关节外科收治的老年膝骨关节炎患者120例为研究对象,采用随机数字表法分为对照组和观察组,各60例。对照组采用全膝关节置换术进行治疗,观察组在全膝关节置换术的术中和术后分别使用氨甲环酸注射液进行治疗,均使用1次,两组术后均随访6个月。比较两组手术相关指标,术前和术后48 h凝血功能,术前和术后6个月膝关节功能,统计两组住院期间并发症发生情况。结果观察组患者术中失血量、隐性失血量、术后引流量均低于对照组(P<0.05),且术后引流时间、创面干燥时间、创面愈合时间均短于对照组(P<0.05)。与术前比较,术后48 h两组凝血酶原时间(PT)、部分凝血活酶时间(APTT)和全血纤维蛋白原(FIB)比较,差异无统计学意义(P>0.05),组间比较,差异无统计学意义(P>0.05)。与术前比较,术后6个月两组疼痛情况、行走稳定情况、行走距离、行走辅助、伸屈情况、肌力水平得分均升高,观察组高于对照组(P<0.05)。观察组患者并发症总发生率为8.33%,对照组患者并发症总发生率为13.33%,组间比较,差异无统计学意义(P>0.05)。结论氨甲环酸可有效减少老年膝骨关节炎患者全膝关节置换术中失血,降低术后引流量,缩短术后引流时间,促进创面愈合,同时改善患者膝关节功能,且对凝血功能影响小,术后并发症少。

稻壳粉添加剂提高污泥的脱水效果研究

利用农业废弃物稻壳粉能有效提高污泥的脱水性能。该文研究了稻壳粉投加量对污泥脱水性能的影响及调理机理,同时分析稻壳粉调理对污泥滤液和脱水后污泥主要性质的影响,并进行技术经济分析。试验结果表明,稻壳粉的最佳投加量为70%污泥干质量(DS);在最佳调理条件下,与单独投加三氯化铁(FeCl_3,138.09g/kg)相比,污泥比阻降低了59.73%,污泥净产率提高了45.27%,污泥泥饼的含固率从13.99%提高到23.97%;扫描电镜结果表明,稻壳粉调理后的污泥泥饼具有不可压缩性和可渗透性,有利于污泥中水分的脱出;同时,稻壳粉的投加可有效降低滤液浊度和溶解性化学需氧量。因此,利用稻壳粉来调理污泥具有较大的潜力。

香蕉皮改性材料对废水中二价Cd离子的吸附特性与机理

为探究农业生物质制备绿色吸附材料处理含Cd^(2+)废水方法,以香蕉皮为原料,制备改性吸附材料。采用单因素试验,优化了改性工艺条件。通过静态吸附试验,结合等温模型和吸附动力学模型探讨了其对Cd^(2+)吸附过程。利用比表面及孔径分析(brunner-emmet-teller)、扫描电镜(scanning electron microscope)、能谱仪(energy disperse spectroscopy)、元素分析仪、傅里叶变换红外光谱(Fourier transform infrared spectroscopy)等手段对改性前后材料的表面形态和结构进行表征,并分析了改性和吸附过程的机理。结果表明:改性较佳工艺条件为Na OH浓度为0.25 mol/L,改性时间为30 min。在此条件下香蕉皮改性后,对水中Cd^(2+)的理论饱和吸附量由37.61 mg/g提高到87.15 mg/g,平衡时间由60 min缩短到45 min。吸附符合Langmuir等温模型(R^2=0.998)和准二级动力学模型(R2=0.999)。改性后的香蕉皮对水中Cd^(2+)的吸附以离子交换吸附为主。研究结果可为木质纤维素生物质改性制备绿色吸附材料处理含重金属废水提供理论依据。

Inflammatory myofibroblastic tumor successfully treated with chemotherapy and nonsteroidals:A case report

Inflammatory myofibroblastic tumor(IMT) occurring at retroperitoneal sites has rarely been reported.We report the case of a previously well 14-year-old girl with no history of abdominal disease whose past medical history and family tumor history were unremarkable.She complained of intermittent abdominal pain for one month.An abdominal mass was found on physical examination and abdominal contrast-enhanced computed tomography(CT) showed a hypodense soft mass,the size and location of which suggested a well delineated retroperitoneal tumor surrounding the superior mesenteric vessels measuring 3.3 cm × 4.5 cm × 4.5 cm with enlarged lymph nodes.The patient underwent an exploratory laparotomy followed by biopsy and was subsequently diagnosed with retroperitoneal IMT.She was successfully treated with postoperative chemotherapy and oral diclofenac sodium.Following completion of therapy the mass was no longer palpable and no longer visible on CT scanning.The use of methotrexate and cisplatin for aggressive myofibroblastic tumors is also reviewed.

Synthesis of a New Rigid Bicyclic AMPP Ligand (TIAMPP) and Application in Asymmetric Hydrogenation

The new rigid bicyclic AMPP（（S）-TIAMPP） has been synthesized from the corresponding Ticol and Ph2PCI. The application of （S）-TIAMPP in Rh-catalyzed asymmetric hydrogenation of α-dehydroamino acids derivatives has been examined. Up to 93% ee was obtained.

基于优化卷积神经网络结构的人体行为识别

为了提高卷积神经网络对非线性特征以及复杂图像隐含的抽象特征提取能力,提出优化卷积神经网络结构的人体行为识别方法。通过优化卷积神经网络模型,构建嵌套Maxout多层感知器层的网络结构,增强卷积神经网络的卷积层对前景目标特征提取能力。通过嵌套Maxout多层感知器层网络结构可以线性地组合特征图并选择最有效特征信息,获取的特征图经过矢量化处理,分类器Softmax完成人体行为识别。仿真实验结果表明,该方法对人体行为识别准确率取得较好结果。

基于DES算法与RSA算法的数据加密技术在电子商务中的应用

随着电子商务的迅猛发展,交易中数据传输的保密性和安全性要求日益提高。采取分析和比较方法,对目前常用的对称加密算法DES、非对称加密算法RSA进行了研究,阐述了两者的运算过程。在比较优缺点的基础上,利用公开密钥技术的SSL协议(安全套接层协议)和SET交易协议,根据电子商务交易过程需求选择算法,既能迅速对数据进行加解密,又能有效提升运算效率。

基于ABAQUS的底部钻具组合下垂误差校正分析

井眼轨迹姿态计算精确度受井斜角、方位角以及测深三个关键参数影响,其中底部钻具组合下垂误差是影响井眼轨迹计算精度的主要误差源,对底部钻具组合下垂误差的精确校正能够使井眼轨迹更接近真实值。参照实钻井眼钻具组合,借用ABAQUS仿真软件构建重力场下底部钻具组合受力变形分析模型,求解钻柱轴线各点下垂误差值并获取测点位置下垂误差校正曲线。结果显示,底部钻具组合下垂误差随井斜的增大而增大,在水平井段达到最大值,且该值受传感器安放位置影响,最后用实际测井数据进行验证。

物联网环境下档案馆智能监控系统研究

针对档案馆安防系统存在维护成本高、移动性能差等缺点,提出一种基于物联网技术的档案馆智能监控系统。以Raspberry Pi嵌入式平台作为系统中央控制服务器,Arduino作为控制器,智能手机为移动终端。系统具有安全事务报警、报警记录生成、现场图像拍摄、预警信息传送、实时远程监控、本地和远程设置阈值、智能控制馆内环境信息等功能,对档案馆进行安全防范和远程智能控制。实验测试结果显示,该系统能有效进行智能监控,提高移动性能,降低投入成本,具有良好的应用前景。