The nonlinear behavior of a soil-foundation system may alter the seismic response of a structure by providing additional flexibility to the system and dissipating hysteretic energy at the soil-foundation interface. Ho...The nonlinear behavior of a soil-foundation system may alter the seismic response of a structure by providing additional flexibility to the system and dissipating hysteretic energy at the soil-foundation interface. However, the current design practice is still reluctant to consider the nonlinearity of the soil-foundation system, primarily due to lack of reliable modeling techniques. This study is motivated towards evaluating the effect of nonlinear soil-structure interaction （SSI） on the seismic responses of low-rise steel moment resisting frame （SMRF） structures. In order to achieve this, a Winkler- based approach is adopted, where the soil beneath the foundation is assumed to be a system of closely-spaced, independent, nonlinear spring elements. Static pushover analysis and nonlinear dynamic analyses are performed on a 3-story SMRF building and the performance of the structure is evaluated through a variety of force and displacement demand parameters. It is observed that incorporation of nonlinear SSI leads to an increase in story displacement demand and a significant reduction in base moment, base shear and inter-story drift demands, indicating the importance of its consideration towards achieving an economic, yet safe seismic design.展开更多
Body mass index(BMI)and breast cancer biomarkers(BCBs)such as resistin,leptin adiponectin,monocyte chemoattractant protein-1(MCP-1)and homeostasis model assessment of insulin resistance(HOMA-IR)are highly associated w...Body mass index(BMI)and breast cancer biomarkers(BCBs)such as resistin,leptin adiponectin,monocyte chemoattractant protein-1(MCP-1)and homeostasis model assessment of insulin resistance(HOMA-IR)are highly associated with each other.The report has focused the inter-relationship between BMI and BCBs based on probabilistic modeling.It has been shown that mean BMI is directly associated with leptin(P<0.0001)and MCP-1(P=0.0002),while it is inversely associated with adiponectin(P=0.0003),HOMA-IR(P<0.0001),and it is higher for healthy women(P=0.0116)than breast cancer women.In addition,variance of BMI is inversely associated with resistin(P=0.1450).On the other hand,mean MCP-1 is directly associated with BMI(P<0.0001).Mean resistin is directly associated with the interaction effect of BMI and leptin(BMI^*Leptin)(P=0.0415),while its variance is directly associated with BMI(P=0.0942),and it is inversely associated with BMI*Adiponectin(P=0.1518).Leptin is directly associated with BMI(P<0.0001).Also adiponectin is inversely associated with BMI(P<0.0001),BMI*Leptin(P=0.1729),while it is directly associated with Age^*BMI(P=0.0017)and BMI^*Resistin(P=0.0615).It can be concluded that BMI and BCBs are strongly associated with each other.Care should be taken on BMI for breast cancer women.展开更多
A scheme for the generation of a pseudo noise(PN)sequence in the optical domain is proposed.The cascaded units of micro-ring resonator(MRR)-based D flip-flop are used to design the device.D flip-flops consist of a sin...A scheme for the generation of a pseudo noise(PN)sequence in the optical domain is proposed.The cascaded units of micro-ring resonator(MRR)-based D flip-flop are used to design the device.D flip-flops consist of a single MRR and share the same optical pump signal.Numerical analysis is performed,and simulated results are discussed.The proposed device can be used as a building block for optical computing and for creating an information processing system.展开更多
文摘The nonlinear behavior of a soil-foundation system may alter the seismic response of a structure by providing additional flexibility to the system and dissipating hysteretic energy at the soil-foundation interface. However, the current design practice is still reluctant to consider the nonlinearity of the soil-foundation system, primarily due to lack of reliable modeling techniques. This study is motivated towards evaluating the effect of nonlinear soil-structure interaction （SSI） on the seismic responses of low-rise steel moment resisting frame （SMRF） structures. In order to achieve this, a Winkler- based approach is adopted, where the soil beneath the foundation is assumed to be a system of closely-spaced, independent, nonlinear spring elements. Static pushover analysis and nonlinear dynamic analyses are performed on a 3-story SMRF building and the performance of the structure is evaluated through a variety of force and displacement demand parameters. It is observed that incorporation of nonlinear SSI leads to an increase in story displacement demand and a significant reduction in base moment, base shear and inter-story drift demands, indicating the importance of its consideration towards achieving an economic, yet safe seismic design.
文摘Body mass index(BMI)and breast cancer biomarkers(BCBs)such as resistin,leptin adiponectin,monocyte chemoattractant protein-1(MCP-1)and homeostasis model assessment of insulin resistance(HOMA-IR)are highly associated with each other.The report has focused the inter-relationship between BMI and BCBs based on probabilistic modeling.It has been shown that mean BMI is directly associated with leptin(P<0.0001)and MCP-1(P=0.0002),while it is inversely associated with adiponectin(P=0.0003),HOMA-IR(P<0.0001),and it is higher for healthy women(P=0.0116)than breast cancer women.In addition,variance of BMI is inversely associated with resistin(P=0.1450).On the other hand,mean MCP-1 is directly associated with BMI(P<0.0001).Mean resistin is directly associated with the interaction effect of BMI and leptin(BMI^*Leptin)(P=0.0415),while its variance is directly associated with BMI(P=0.0942),and it is inversely associated with BMI*Adiponectin(P=0.1518).Leptin is directly associated with BMI(P<0.0001).Also adiponectin is inversely associated with BMI(P<0.0001),BMI*Leptin(P=0.1729),while it is directly associated with Age^*BMI(P=0.0017)and BMI^*Resistin(P=0.0615).It can be concluded that BMI and BCBs are strongly associated with each other.Care should be taken on BMI for breast cancer women.
文摘A scheme for the generation of a pseudo noise(PN)sequence in the optical domain is proposed.The cascaded units of micro-ring resonator(MRR)-based D flip-flop are used to design the device.D flip-flops consist of a single MRR and share the same optical pump signal.Numerical analysis is performed,and simulated results are discussed.The proposed device can be used as a building block for optical computing and for creating an information processing system.
