Objective:To evaluate the diagnostic pharmacognostical characters of Costus speciosus(aerial parts)along with their physico-chemical parameters and fluorosence analysis.Method:The pharmacognostical characters were det...Objective:To evaluate the diagnostic pharmacognostical characters of Costus speciosus(aerial parts)along with their physico-chemical parameters and fluorosence analysis.Method:The pharmacognostical characters were determined in terms of macroscopy,microscopy,powder microscopy,leaf constant,fluorescence analysis and preliminary phytochemical investigation.Results:The findings of macroscopy revealed that leaves elliptic to oblong or oblong-lancoelate,thick,spirally arranged,with stem clasping sheaths up to 4 cm,flowers large,white,conelike terminal spikes,with bright red bracts.Transverse section of leaflet showed the presence of cuticularised epidermis with polygonal cells on adaxial surface and bluntly angled cells on abaxial surface of lamina,mesophyll cells differentiated in to single layered palisade cells on each surface and 2-3 layered spongy parenchyma,unicellular and uniseriate multicellular covering trichomes,paracytic stomata and vascular bundles surrounded by sclerenchymatous multicellular sheath.Preliminary phytochemical screening exhibited the presence of various phytochemical groups like alkaloids,glycosides,steroids,phenolic constituents.Further,the leaf constants,powder microscopy and fluorescence characteristics indicated outstanding results from this investigation Conclusions:Various pharmacognostical and physico-chemical parameters have pivotal roles in identification,authentication and establishment of quality parameters of the species.展开更多
Objective:To investigate the hepatoprotective activity of ethanolic extract of leaves of Caesalpenia crista(C.crista)against paracetamol induced hepatotoxicity in rats.Methods:Paracetamol(2 g/kg body weight)was used t...Objective:To investigate the hepatoprotective activity of ethanolic extract of leaves of Caesalpenia crista(C.crista)against paracetamol induced hepatotoxicity in rats.Methods:Paracetamol(2 g/kg body weight)was used to induce hepatotoxicity in albino rats.Ethanolic extract of leaves of C.crista was administered at the dose levels of 200 and 400 mg/kg body weight orally for 7 d.Silymarin(100 mg/kg)was used as standard drug.The hepatoprotective effect of ethanolic extract was evaluated by assessment of biochemical parameters such as serum glutamic oxaloacetic transaminase,serum glutamic pyruvic transaminase,serum alkaline phosphatase,bilirubin(total and direct),and triglycerides content.Histopathological study of rat liver was also done.Results:Administration of ethanolic extract at doses 200 mg/kg and 400 mg/kg body weight exhibited significant reduction in elevated level of serum marker enzymes,bilirubin(total and direct)and triglycerides when compared to positive control group.Conclusions:It is concluded that the ethanolic extract of C.crista leaves seems to justify the promising hepatoprotective effect on paracetamol induced liver damage in rats.展开更多
The Acanthaceae family is an important source of therapeutic drugs and the ethno pharmacological knowledge of this family requires urgent documentation as several of its species are near extinction.Justicia is the lar...The Acanthaceae family is an important source of therapeutic drugs and the ethno pharmacological knowledge of this family requires urgent documentation as several of its species are near extinction.Justicia is the largest genus of Acanthaceae with approximately 600 species.Aim of the present review is to present literature for the traditional uses&pharmacological review of Justicia picta(Family:Acanthaceae)and to discuss further priorities of research yet to be discovered.展开更多
Herbal drug therapy is the most trusted system of medicine in countries like India,where people strongly believe in Ayurveda as herbs are the part of rural Indian lifestyle.Most of the diseases which have no medicine ...Herbal drug therapy is the most trusted system of medicine in countries like India,where people strongly believe in Ayurveda as herbs are the part of rural Indian lifestyle.Most of the diseases which have no medicine in allopathic system can be cured successfully by using traditional medicines.Leea indica,a traditional Chinese medicinal plant is the sole member of the family Leeaceae,which is closely related to the economically important grape family,Vitaceae.It is widely distributed from Southern Asia to Northern Oceania.The plant parts are enriched with various bioactive compounds such as gallic acid,quercitrin,β-amyrin,β-sitosterol and lupeol,etc.Traditionally,it is used to treat itchy skin,fever,diarrhea,and body aches.The current review attempts to encompass the available literature on Leea indica with respect to its phytochemistry,traditional uses and gist of its various pharmacological activities.展开更多
文摘Objective:To evaluate the diagnostic pharmacognostical characters of Costus speciosus(aerial parts)along with their physico-chemical parameters and fluorosence analysis.Method:The pharmacognostical characters were determined in terms of macroscopy,microscopy,powder microscopy,leaf constant,fluorescence analysis and preliminary phytochemical investigation.Results:The findings of macroscopy revealed that leaves elliptic to oblong or oblong-lancoelate,thick,spirally arranged,with stem clasping sheaths up to 4 cm,flowers large,white,conelike terminal spikes,with bright red bracts.Transverse section of leaflet showed the presence of cuticularised epidermis with polygonal cells on adaxial surface and bluntly angled cells on abaxial surface of lamina,mesophyll cells differentiated in to single layered palisade cells on each surface and 2-3 layered spongy parenchyma,unicellular and uniseriate multicellular covering trichomes,paracytic stomata and vascular bundles surrounded by sclerenchymatous multicellular sheath.Preliminary phytochemical screening exhibited the presence of various phytochemical groups like alkaloids,glycosides,steroids,phenolic constituents.Further,the leaf constants,powder microscopy and fluorescence characteristics indicated outstanding results from this investigation Conclusions:Various pharmacognostical and physico-chemical parameters have pivotal roles in identification,authentication and establishment of quality parameters of the species.
基金Supported by Teerthanker Mahaveer University,Delhi Road,Bagarpur,Moradabad,Uttar Pradesh,India(Grant No.TMU/TMCOP/2013-14/RES.GRANT-05/PGN).
文摘Objective:To investigate the hepatoprotective activity of ethanolic extract of leaves of Caesalpenia crista(C.crista)against paracetamol induced hepatotoxicity in rats.Methods:Paracetamol(2 g/kg body weight)was used to induce hepatotoxicity in albino rats.Ethanolic extract of leaves of C.crista was administered at the dose levels of 200 and 400 mg/kg body weight orally for 7 d.Silymarin(100 mg/kg)was used as standard drug.The hepatoprotective effect of ethanolic extract was evaluated by assessment of biochemical parameters such as serum glutamic oxaloacetic transaminase,serum glutamic pyruvic transaminase,serum alkaline phosphatase,bilirubin(total and direct),and triglycerides content.Histopathological study of rat liver was also done.Results:Administration of ethanolic extract at doses 200 mg/kg and 400 mg/kg body weight exhibited significant reduction in elevated level of serum marker enzymes,bilirubin(total and direct)and triglycerides when compared to positive control group.Conclusions:It is concluded that the ethanolic extract of C.crista leaves seems to justify the promising hepatoprotective effect on paracetamol induced liver damage in rats.
基金Supported by Teerthanker Mahaveer University,Delhi Road,Bagarpur,Moradabad,Uttar Pradesh,India(Grant No.TMU/TMCOP/2013-14/RES.GRANT-01/PGN).
文摘The Acanthaceae family is an important source of therapeutic drugs and the ethno pharmacological knowledge of this family requires urgent documentation as several of its species are near extinction.Justicia is the largest genus of Acanthaceae with approximately 600 species.Aim of the present review is to present literature for the traditional uses&pharmacological review of Justicia picta(Family:Acanthaceae)and to discuss further priorities of research yet to be discovered.
文摘Herbal drug therapy is the most trusted system of medicine in countries like India,where people strongly believe in Ayurveda as herbs are the part of rural Indian lifestyle.Most of the diseases which have no medicine in allopathic system can be cured successfully by using traditional medicines.Leea indica,a traditional Chinese medicinal plant is the sole member of the family Leeaceae,which is closely related to the economically important grape family,Vitaceae.It is widely distributed from Southern Asia to Northern Oceania.The plant parts are enriched with various bioactive compounds such as gallic acid,quercitrin,β-amyrin,β-sitosterol and lupeol,etc.Traditionally,it is used to treat itchy skin,fever,diarrhea,and body aches.The current review attempts to encompass the available literature on Leea indica with respect to its phytochemistry,traditional uses and gist of its various pharmacological activities.
