Background: Congenital heart defect exists from birth but is usually detected in a later stage of life, as in case of quadricuspid aortic valve. A great majority of quadricuspid aortic valves do not have a normal func...Background: Congenital heart defect exists from birth but is usually detected in a later stage of life, as in case of quadricuspid aortic valve. A great majority of quadricuspid aortic valves do not have a normal function and often necessitate surgical treatment. Aim: To report a case with quadricuspid aortic valve accompanied with complications. Case Presentation: We present a case of a male detected with quadricuspid aortic valve of four equal sized cusps accompanied by abnormalities, yet managed successfully under conservative treatment. Conclusion: Patients with a quadricuspid aortic valve require careful clinical evaluation and close follow up.展开更多
Familial hypercholesterolemia is an autosomal dominant genetic disease due to mutation in low-density lipoprotein-cholesterol receptor gene. It is characterized by elevated plasma low-density lipoprotein-cholesterol a...Familial hypercholesterolemia is an autosomal dominant genetic disease due to mutation in low-density lipoprotein-cholesterol receptor gene. It is characterized by elevated plasma low-density lipoprotein-cholesterol and the consequence of which leads to premature cardiovascular disease. The mainstay in the management of familial hypercholesterolemia patient is the treatment with high potency statin. However, current research shows influence of the type of low-density lipoprotein-cholesterol receptor mutations on severity of the cardiovascular disease, lipid profile, and response to statin treatment. We are here presenting a case of young Indian female patient who was diagnosed with familial hypercholesterolemia and treated with percutaneous transluminal coronary angioplasty in view of double vessel disease in the third decade of her life. She was prescribed with statin therapy for elevated low-density lipoprotein cholesterol. After 3 years, she presented once again with a triple vessel disease along with patent stented segments and abnormal lipid profile.展开更多
文摘Background: Congenital heart defect exists from birth but is usually detected in a later stage of life, as in case of quadricuspid aortic valve. A great majority of quadricuspid aortic valves do not have a normal function and often necessitate surgical treatment. Aim: To report a case with quadricuspid aortic valve accompanied with complications. Case Presentation: We present a case of a male detected with quadricuspid aortic valve of four equal sized cusps accompanied by abnormalities, yet managed successfully under conservative treatment. Conclusion: Patients with a quadricuspid aortic valve require careful clinical evaluation and close follow up.
文摘Familial hypercholesterolemia is an autosomal dominant genetic disease due to mutation in low-density lipoprotein-cholesterol receptor gene. It is characterized by elevated plasma low-density lipoprotein-cholesterol and the consequence of which leads to premature cardiovascular disease. The mainstay in the management of familial hypercholesterolemia patient is the treatment with high potency statin. However, current research shows influence of the type of low-density lipoprotein-cholesterol receptor mutations on severity of the cardiovascular disease, lipid profile, and response to statin treatment. We are here presenting a case of young Indian female patient who was diagnosed with familial hypercholesterolemia and treated with percutaneous transluminal coronary angioplasty in view of double vessel disease in the third decade of her life. She was prescribed with statin therapy for elevated low-density lipoprotein cholesterol. After 3 years, she presented once again with a triple vessel disease along with patent stented segments and abnormal lipid profile.
