Osteoarthritis(OA)is a regressive ailment that affects a large population of patients.The most common symptoms of OA in humans are cartilage abnormalities.Hydrogels are excellent candidates for cartilage regeneration ...Osteoarthritis(OA)is a regressive ailment that affects a large population of patients.The most common symptoms of OA in humans are cartilage abnormalities.Hydrogels are excellent candidates for cartilage regeneration and are widely accepted as implants.In the past few decades,numerous types of hydrogels have been synthesized to repair cartilage defects.This study highlights recent advances in hydrogel development for the treatment of cartilage defects.In addition,the detailed progression of tailored nanocomposite hydrogels is summarized,and emphasis has been placed on the mechanical properties,especially the tribological behavior of the developed nanocomposite hydrogels.展开更多
文摘Osteoarthritis(OA)is a regressive ailment that affects a large population of patients.The most common symptoms of OA in humans are cartilage abnormalities.Hydrogels are excellent candidates for cartilage regeneration and are widely accepted as implants.In the past few decades,numerous types of hydrogels have been synthesized to repair cartilage defects.This study highlights recent advances in hydrogel development for the treatment of cartilage defects.In addition,the detailed progression of tailored nanocomposite hydrogels is summarized,and emphasis has been placed on the mechanical properties,especially the tribological behavior of the developed nanocomposite hydrogels.