Empirical mode decomposition (EMD) is an adaptive and approximately orthogonal filtering process that reflects human’s visual mechanism of differentiating textures. In this paper, we present a modified 2D EMD algorit...Empirical mode decomposition (EMD) is an adaptive and approximately orthogonal filtering process that reflects human’s visual mechanism of differentiating textures. In this paper, we present a modified 2D EMD algorithm using the FastRBF and an appropriate number of iterations in the shifting process (SP), then apply it to texture classification. Rotation-invariant texture feature vectors are extracted using auto-registration and circular regions of magnitude spectra of 2D fast Fourier transform (FFT). In the experiments, we employ a Bayesion classifier to classify a set of 15 distinct natural textures selected from the Brodatz album. The experimental results, based on different testing datasets for images with different orientations, show the effectiveness of the proposed classification scheme.展开更多
目的:研究艾拉莫德(IGU)与甲氨蝶呤(MTX)治疗类风湿关节炎(RA)的有效性及安全性。方法:对我院就诊的活动期RA患者120例,随机分为3组,MTX组、IGU组、MTX+IGU组,每组各40例。治疗24 w后进行疗效及安全性评估。结果:治疗后,MTX组ACR20(20%...目的:研究艾拉莫德(IGU)与甲氨蝶呤(MTX)治疗类风湿关节炎(RA)的有效性及安全性。方法:对我院就诊的活动期RA患者120例,随机分为3组,MTX组、IGU组、MTX+IGU组,每组各40例。治疗24 w后进行疗效及安全性评估。结果:治疗后,MTX组ACR20(20%美国风湿病学会标准改善率)有19例(47.5%),IGU组ACR20有20例(50.0%),MTX+IGU组ACR20有29例(72.5%),MTX+IGU组明显优于单药治疗组,3组比较有统计学意义( P <0.05)。治疗后DAS28(完全缓解率)比较无统计学差异,MTX+IGU组DAS28比例最高(27.5%),高于MTX组(12.5%)及IGU组(15.0%)。比较ACR标准各个项目均有所好转,且IGU与MTX疗效相当,MTX+IGU优于单药治疗,3组比较有统计学意义。不同治疗组不良反应发生率无显著性差异。结论:本研究显示IGU、MTX治疗活动期RA的疗效及安全性无显著差异,MTX+IGU治疗优于单药治疗且具有良好的安全性,可为临床用药提供参考。展开更多
In the present paper,a new criterion is derived to obtain the optimum fitting curve while using Cubic B-spline basis functions to remove the statistical noise in the spectroscopic data.In this criterion,firstly,smooth...In the present paper,a new criterion is derived to obtain the optimum fitting curve while using Cubic B-spline basis functions to remove the statistical noise in the spectroscopic data.In this criterion,firstly,smoothed fitting curves using Cubic B-spline basis functions are selected with the increasing knot number.Then,the best fitting curves are selected according to the value of the minimum residual sum of squares(RSS)of two adjacent fitting curves.In the case of more than one best fitting curves,the authors use Reinsch's first condition to find a better one.The minimum residual sum of squares(RSS)of fitting curve with noisy data is not recommended as the criterion to determine the best fitting curve,because this value decreases to zero as the number of selected channels increases and the minimum value gives no smoothing effect.Compared with Reinsch's method,the derived criterion is simple and enables the smoothing conditions to be determined automatically without any initial input parameter.With the derived criterion,the satisfactory result was obtained for the experimental spectroscopic data to remove the statistical noise using Cubic B-spline basis functions.展开更多
基金Project supported by the National Basic Research Program (973) of China (Nos. 2004CB318000 and 2002CB312104), the National Natural Science Foundation of China (Nos. 60133020 and 60325208) and the Natural Science Foundation of Beijing (No. 1062006), China
文摘Empirical mode decomposition (EMD) is an adaptive and approximately orthogonal filtering process that reflects human’s visual mechanism of differentiating textures. In this paper, we present a modified 2D EMD algorithm using the FastRBF and an appropriate number of iterations in the shifting process (SP), then apply it to texture classification. Rotation-invariant texture feature vectors are extracted using auto-registration and circular regions of magnitude spectra of 2D fast Fourier transform (FFT). In the experiments, we employ a Bayesion classifier to classify a set of 15 distinct natural textures selected from the Brodatz album. The experimental results, based on different testing datasets for images with different orientations, show the effectiveness of the proposed classification scheme.
文摘目的:研究艾拉莫德(IGU)与甲氨蝶呤(MTX)治疗类风湿关节炎(RA)的有效性及安全性。方法:对我院就诊的活动期RA患者120例,随机分为3组,MTX组、IGU组、MTX+IGU组,每组各40例。治疗24 w后进行疗效及安全性评估。结果:治疗后,MTX组ACR20(20%美国风湿病学会标准改善率)有19例(47.5%),IGU组ACR20有20例(50.0%),MTX+IGU组ACR20有29例(72.5%),MTX+IGU组明显优于单药治疗组,3组比较有统计学意义( P <0.05)。治疗后DAS28(完全缓解率)比较无统计学差异,MTX+IGU组DAS28比例最高(27.5%),高于MTX组(12.5%)及IGU组(15.0%)。比较ACR标准各个项目均有所好转,且IGU与MTX疗效相当,MTX+IGU优于单药治疗,3组比较有统计学意义。不同治疗组不良反应发生率无显著性差异。结论:本研究显示IGU、MTX治疗活动期RA的疗效及安全性无显著差异,MTX+IGU治疗优于单药治疗且具有良好的安全性,可为临床用药提供参考。
基金Supported by the Science and Technology Development Fund of Macao(China)grant(No.042/2007/A3,No.003/2008/A1)partly supported by NSFC Project(No.10631080)National Key Basic Research Project of China grant(No.2004CB318000)
文摘In the present paper,a new criterion is derived to obtain the optimum fitting curve while using Cubic B-spline basis functions to remove the statistical noise in the spectroscopic data.In this criterion,firstly,smoothed fitting curves using Cubic B-spline basis functions are selected with the increasing knot number.Then,the best fitting curves are selected according to the value of the minimum residual sum of squares(RSS)of two adjacent fitting curves.In the case of more than one best fitting curves,the authors use Reinsch's first condition to find a better one.The minimum residual sum of squares(RSS)of fitting curve with noisy data is not recommended as the criterion to determine the best fitting curve,because this value decreases to zero as the number of selected channels increases and the minimum value gives no smoothing effect.Compared with Reinsch's method,the derived criterion is simple and enables the smoothing conditions to be determined automatically without any initial input parameter.With the derived criterion,the satisfactory result was obtained for the experimental spectroscopic data to remove the statistical noise using Cubic B-spline basis functions.
