Because of the small size of coronary plaque and its continuous beating with the heart,the assessment of the nature of coronary atherosclerotic plaques by magnetic resonance imaging remains a challenge in current rese...Because of the small size of coronary plaque and its continuous beating with the heart,the assessment of the nature of coronary atherosclerotic plaques by magnetic resonance imaging remains a challenge in current research.Recent studies have shown that changes in the pericoronary fat environment are closely related to the nature of coronary atherosclerotic plaques.At present,the new multi-modal magnetic resonance technology can quantitatively assess the changes of pericorral fat environment,which is expected to effectively evaluate the properties of coronary artery plaque.Therefore,it is of greater clinical importance to study pericoronary fat.Advances in the biological significance of pericoronary fat,comparative imaging for pericoronary fat assessment and clinical applications of its imaging will be reviewed.展开更多
水通道蛋白-4(aquaporin-4,AQP4)是一种具有高度选择性的膜蛋白,它对机体维持细胞内外环境水平衡具有重要意义,研究发现AQP4异常表达与许多疾病的发生有关。脑水肿是脑创伤最常见、最严重的并发症,其发病机制与AQP4密切相关。多模态磁...水通道蛋白-4(aquaporin-4,AQP4)是一种具有高度选择性的膜蛋白,它对机体维持细胞内外环境水平衡具有重要意义,研究发现AQP4异常表达与许多疾病的发生有关。脑水肿是脑创伤最常见、最严重的并发症,其发病机制与AQP4密切相关。多模态磁共振成像(multimodal magnetic resonance imaging,M-MRI)技术的发展为创伤性脑水肿的精准诊断提供了影像依据。近年来AQP4与MRI的相关性研究已成为热点。本文就AQP4在创伤性脑水肿组织中的表达及MRI的相关性研究进展进行综述。展开更多
基金Hainan Provincial Natural Science Foundation of China(822RC873)Sanya Medical Science and Technology Innovation Project of China(2019YW01)。
文摘Because of the small size of coronary plaque and its continuous beating with the heart,the assessment of the nature of coronary atherosclerotic plaques by magnetic resonance imaging remains a challenge in current research.Recent studies have shown that changes in the pericoronary fat environment are closely related to the nature of coronary atherosclerotic plaques.At present,the new multi-modal magnetic resonance technology can quantitatively assess the changes of pericorral fat environment,which is expected to effectively evaluate the properties of coronary artery plaque.Therefore,it is of greater clinical importance to study pericoronary fat.Advances in the biological significance of pericoronary fat,comparative imaging for pericoronary fat assessment and clinical applications of its imaging will be reviewed.
文摘水通道蛋白-4(aquaporin-4,AQP4)是一种具有高度选择性的膜蛋白,它对机体维持细胞内外环境水平衡具有重要意义,研究发现AQP4异常表达与许多疾病的发生有关。脑水肿是脑创伤最常见、最严重的并发症,其发病机制与AQP4密切相关。多模态磁共振成像(multimodal magnetic resonance imaging,M-MRI)技术的发展为创伤性脑水肿的精准诊断提供了影像依据。近年来AQP4与MRI的相关性研究已成为热点。本文就AQP4在创伤性脑水肿组织中的表达及MRI的相关性研究进展进行综述。
