Our research has identified a couple of near-infrared(NIR)heptamethine indocyanine dyes exhibiting preferential tumor accumnulation property for in vriwo imaging.On the basis of our foregoing work,we describe here a p...Our research has identified a couple of near-infrared(NIR)heptamethine indocyanine dyes exhibiting preferential tumor accumnulation property for in vriwo imaging.On the basis of our foregoing work,we describe here a preliminary structure-activity relationship(SAR)study of 11 related heptamethine indocyanine dyes and several essential requirements of these structures for in vivo tumor-targeted imaging.展开更多
基金supported by State Key Basic Research Development Program(2012CB518103)Natural Science Foundation Programs(81072523 and 81130026)+1 种基金Chongqing Municipal Natural Sci-ence Foundation Program(CSTC2009BA5043)a program of New Century Excellent Talents in University(NCET)from Ministry of Education to C.S.
文摘Our research has identified a couple of near-infrared(NIR)heptamethine indocyanine dyes exhibiting preferential tumor accumnulation property for in vriwo imaging.On the basis of our foregoing work,we describe here a preliminary structure-activity relationship(SAR)study of 11 related heptamethine indocyanine dyes and several essential requirements of these structures for in vivo tumor-targeted imaging.