On the basis of a series of control experiments and nuclear magnetic resonance analyses,it is discovered that Boc-protected amino acid ligand coordinated to Pd center is partly replaced by N,N-dimethylformamide,and H2...On the basis of a series of control experiments and nuclear magnetic resonance analyses,it is discovered that Boc-protected amino acid ligand coordinated to Pd center is partly replaced by N,N-dimethylformamide,and H2O can inhibit coordination of N,N-dimethylformamide to Pd center.The novel action mechanism perfectly explains H2O promotion for stereoselectivity in Pd(II)-catalyzed C—H aryiation of diarylphosphinamides with arylboronic acids.展开更多
基金Supported by the National Natural Science Foundation of China(No.21772190).
文摘On the basis of a series of control experiments and nuclear magnetic resonance analyses,it is discovered that Boc-protected amino acid ligand coordinated to Pd center is partly replaced by N,N-dimethylformamide,and H2O can inhibit coordination of N,N-dimethylformamide to Pd center.The novel action mechanism perfectly explains H2O promotion for stereoselectivity in Pd(II)-catalyzed C—H aryiation of diarylphosphinamides with arylboronic acids.
