The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the...The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the on-orbit performance of our newly developed Sc/Si multi-layer reflecting mirror and the 2k×2k EUV CMOS imaging camera and to take full-disk solar images at the Ne VII 46.5 nm spectral line with a filter width of~3 nm.SUTRI employs a Ritchey-Chrétien optical system with an aperture of 18 cm.The on-orbit observations show that SUTRI images have a field of view of~416×416 and a moderate spatial resolution of~8″without an image stabilization system.The normal cadence of SUTRI images is 30 s and the solar observation time is about16 hr each day because the earth eclipse time accounts for about 1/3 of SATech-01's orbit period.Approximately15 GB data is acquired each day and made available online after processing.SUTRI images are valuable as the Ne VII 46.5 nm line is formed at a temperature regime of~0.5 MK in the solar atmosphere,which has rarely been sampled by existing solar imagers.SUTRI observations will establish connections between structures in the lower solar atmosphere and corona,and advance our understanding of various types of solar activity such as flares,filament eruptions,coronal jets and coronal mass ejections.展开更多
Cation-disordered rocksalt oxides(DRX)have been identified as promising cathode materials for high energy density applications owing to their variable elemental composition and cationic-anionic redox activity.However,...Cation-disordered rocksalt oxides(DRX)have been identified as promising cathode materials for high energy density applications owing to their variable elemental composition and cationic-anionic redox activity.However,their practical implementation has been impeded by unwanted phenomena such as irrepressible transition metal migration/dissolution and O_(2)/CO_(2)evolution,which arise due to parasitic reactions and densification-degradation mechanisms during extended cycling.To address these issues,a micron-sized DRX cathode Li_(1.2)Ni_(1/3)Ti_(1/3)W_(2/15)O_(1.85)F_(0.15)(SLNTWOF)with F substitution and ultrathin LiF coating layer is developed by alcohols assisted sol-gel method.Within this fluorination-induced integrated structure design(FISD)strategy,in-situ F substitution modifies the activity/reversibility of the cationic-anionic redox reaction,while the ultrathin LiF coating and single-crystal structure synergistically mitigate the cathode/electrolyte parasitic reaction and densification-degradation mechanism.Attributed to the multiple modifications and size effect in the FISD strategy,the SLNTWOF sample exhibits reversible cationic-anionic redox chemistry with a meliorated reversible capacity of 290.3 mA h g^(-1)at 0.05C(1C=200 mA g^(-1)),improved cycling stability of 78.5%capacity retention after 50 cycles at 0.5 C,and modified rate capability of 102.8 mA h g^(-1)at 2 C.This work reveals that the synergistic effects between bulk structure modification,surface regulation,and engineering particle size can effectively modulate the distribution and evolution of cationic-anionic redox activities in DRX cathodes.展开更多
The Solar Upper Transition Region Imager(SUTRI)focuses on the solar transition region to achieve dynamic imaging observation of the upper transition region.In this paper,we report the optical system design,mechanical ...The Solar Upper Transition Region Imager(SUTRI)focuses on the solar transition region to achieve dynamic imaging observation of the upper transition region.In this paper,we report the optical system design,mechanical design,ultrasmooth mirror manufacture and measurement,EUV multilayer film coating,prelaunch installation and calibration for the SUTRI payload at IPOE,Tongji University.Finally,the SUTRI carried by the SATech-01 satellite was successfully set to launch.All functions of this telescope were normal,and the observation results obtained in orbit were consistent with the design.展开更多
Objective:Rheumatoid arthritis(RA)is a chronic inflammatory and destructive arthritis,characterized by inflammatory infiltration and bone destruction.Huangqi Guizhi Wuwu Decoction(HGWD)is traditional Chinese medicine,...Objective:Rheumatoid arthritis(RA)is a chronic inflammatory and destructive arthritis,characterized by inflammatory infiltration and bone destruction.Huangqi Guizhi Wuwu Decoction(HGWD)is traditional Chinese medicine,which has been applied in the treatment of RA in clinical.The aim of this study was to investigate the therapeutic effect of HGWD on collagen-induced arthritis(CIA)mouse model.Methods:DBA/1J female mice were used to establish the collagen-induced arthritis(CIA)model.HGWD was administered intragastrically once a day for four weeks starting on the 22nd day after the first immunization.The body weight,hind paw thickness and clinical score were measured every five days.Gait analysis,histopathological staining,enzyme-linked immunosorbent assay(ELISA),ultrasound imaging and micro-computed tomography imaging were performed to determine the effects of HGWD treatment on inflammation and bone structure in this model.Moreover,Real-time PCR and Western blot analysis were used to detect inflammatory factors mRNA and protein levels after HGWD intervention in RAW 264.7 cells.Results:HGWD attenuated symptoms of arthritis,suppressed inflammatory synovium area and the serum levels of inflammatory factors,inhibited joint space enlargement in the knee and ankle joints,reduced numbers of osteoclasts,protected bone destruction,as well as improved motor function.HGWD decreased the expression of mRNA for inflammatory factors and the protein expression levels of p-NF-rB and IL-17.Conclusion:These results suggested that HGWD suppresses inflammation,attenuates bone erosion and maintains motor function in collagen-induced arthritis mice.展开更多
基金supported by the National Natural Science Foundation of China(NSFC)under Grants 11825301,12003016,12073077the National Key R&D Program of China No.2021YFA0718600+1 种基金the Strategic Priority Research Program of the Chinese Academy of Sciences with the Grant No.XDA15018400the Youth Innovation Promotion Association of CAS(2023061)。
文摘The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the on-orbit performance of our newly developed Sc/Si multi-layer reflecting mirror and the 2k×2k EUV CMOS imaging camera and to take full-disk solar images at the Ne VII 46.5 nm spectral line with a filter width of~3 nm.SUTRI employs a Ritchey-Chrétien optical system with an aperture of 18 cm.The on-orbit observations show that SUTRI images have a field of view of~416×416 and a moderate spatial resolution of~8″without an image stabilization system.The normal cadence of SUTRI images is 30 s and the solar observation time is about16 hr each day because the earth eclipse time accounts for about 1/3 of SATech-01's orbit period.Approximately15 GB data is acquired each day and made available online after processing.SUTRI images are valuable as the Ne VII 46.5 nm line is formed at a temperature regime of~0.5 MK in the solar atmosphere,which has rarely been sampled by existing solar imagers.SUTRI observations will establish connections between structures in the lower solar atmosphere and corona,and advance our understanding of various types of solar activity such as flares,filament eruptions,coronal jets and coronal mass ejections.
基金supported by the National Key R&D Program of China(2021YFB2401800)the National Natural Science Foundation of China(22179008,21875022)+2 种基金the Natural Science Foundation of Chongqing,China(cstc2020jcyj-msxmX0589,cstc2020jcyjmsxmX0654)the support from Beijing Institute of Technology Research Fund Program for Young Scholarsthe 4B7B beamlines radiation equipment of Beijing Synchrotron Radiation Facility(2021-BEPC-PT-005924,2021-BEPC-PT-005967)。
文摘Cation-disordered rocksalt oxides(DRX)have been identified as promising cathode materials for high energy density applications owing to their variable elemental composition and cationic-anionic redox activity.However,their practical implementation has been impeded by unwanted phenomena such as irrepressible transition metal migration/dissolution and O_(2)/CO_(2)evolution,which arise due to parasitic reactions and densification-degradation mechanisms during extended cycling.To address these issues,a micron-sized DRX cathode Li_(1.2)Ni_(1/3)Ti_(1/3)W_(2/15)O_(1.85)F_(0.15)(SLNTWOF)with F substitution and ultrathin LiF coating layer is developed by alcohols assisted sol-gel method.Within this fluorination-induced integrated structure design(FISD)strategy,in-situ F substitution modifies the activity/reversibility of the cationic-anionic redox reaction,while the ultrathin LiF coating and single-crystal structure synergistically mitigate the cathode/electrolyte parasitic reaction and densification-degradation mechanism.Attributed to the multiple modifications and size effect in the FISD strategy,the SLNTWOF sample exhibits reversible cationic-anionic redox chemistry with a meliorated reversible capacity of 290.3 mA h g^(-1)at 0.05C(1C=200 mA g^(-1)),improved cycling stability of 78.5%capacity retention after 50 cycles at 0.5 C,and modified rate capability of 102.8 mA h g^(-1)at 2 C.This work reveals that the synergistic effects between bulk structure modification,surface regulation,and engineering particle size can effectively modulate the distribution and evolution of cationic-anionic redox activities in DRX cathodes.
基金the National Key R&D Program of China(2022YFF0709101)the National Natural Science Foundation of China(NSFC)under grant Nos.61621001,62105244,12003016 and 12204353.
文摘The Solar Upper Transition Region Imager(SUTRI)focuses on the solar transition region to achieve dynamic imaging observation of the upper transition region.In this paper,we report the optical system design,mechanical design,ultrasmooth mirror manufacture and measurement,EUV multilayer film coating,prelaunch installation and calibration for the SUTRI payload at IPOE,Tongji University.Finally,the SUTRI carried by the SATech-01 satellite was successfully set to launch.All functions of this telescope were normal,and the observation results obtained in orbit were consistent with the design.
基金sponsored by National Natural Science Foundation(No.81822050,81920108032,81904227)Shanghai“Science and Technology Innovation Action Plan”Medical Innovation Research Project(No.21Y11921400)+4 种基金the Program for Innovative Research Team of Ministry of Science and Technology of China(No.2015RA4002)“Innovation Team”Development Projects(No.IRT1270)Innovative Team Project of Scientific Research Project of Traditional Chinese Medicine of Shanghai Municipal Health Commission(No.2022CX001)Shanghai TCM Medical Center of Chronic Disease(No.2022ZZ01009)Jing'an District Health Research Project of Shanghai(No.2022MS03).
文摘Objective:Rheumatoid arthritis(RA)is a chronic inflammatory and destructive arthritis,characterized by inflammatory infiltration and bone destruction.Huangqi Guizhi Wuwu Decoction(HGWD)is traditional Chinese medicine,which has been applied in the treatment of RA in clinical.The aim of this study was to investigate the therapeutic effect of HGWD on collagen-induced arthritis(CIA)mouse model.Methods:DBA/1J female mice were used to establish the collagen-induced arthritis(CIA)model.HGWD was administered intragastrically once a day for four weeks starting on the 22nd day after the first immunization.The body weight,hind paw thickness and clinical score were measured every five days.Gait analysis,histopathological staining,enzyme-linked immunosorbent assay(ELISA),ultrasound imaging and micro-computed tomography imaging were performed to determine the effects of HGWD treatment on inflammation and bone structure in this model.Moreover,Real-time PCR and Western blot analysis were used to detect inflammatory factors mRNA and protein levels after HGWD intervention in RAW 264.7 cells.Results:HGWD attenuated symptoms of arthritis,suppressed inflammatory synovium area and the serum levels of inflammatory factors,inhibited joint space enlargement in the knee and ankle joints,reduced numbers of osteoclasts,protected bone destruction,as well as improved motor function.HGWD decreased the expression of mRNA for inflammatory factors and the protein expression levels of p-NF-rB and IL-17.Conclusion:These results suggested that HGWD suppresses inflammation,attenuates bone erosion and maintains motor function in collagen-induced arthritis mice.
