This paper reports the primary results of the study on β-lactam derivatives of 2,4-diaryl-2, 3-di hydro-1, 5 -benzothiazepines. Five titie compounds have been synthesized, and their configUration and conformation wer...This paper reports the primary results of the study on β-lactam derivatives of 2,4-diaryl-2, 3-di hydro-1, 5 -benzothiazepines. Five titie compounds have been synthesized, and their configUration and conformation were detendned by X-ray crystallographic analysis.展开更多
The modified Hofmann degradation of koumine(1) has proved abortive. The struture and stereochemistry of the main product(3) were deduced by spectral methods and confirmed by X-ray diffration analysis. From the roots o...The modified Hofmann degradation of koumine(1) has proved abortive. The struture and stereochemistry of the main product(3) were deduced by spectral methods and confirmed by X-ray diffration analysis. From the roots of Gelsemium elegans, dihydrokounine was first isolated as a natural product.展开更多
The neuroexcitotoxic nonprotein amino acidβ-N-oxalo-L-α,β-diaminopropionic acid(β-N-ODAP)and its isomer a-N-oxalo-L-α,β-diaminopropionic acid(α-N-ODAP)in Panax ginseng C.A.Meyer(cultivated ih Northeastern China...The neuroexcitotoxic nonprotein amino acidβ-N-oxalo-L-α,β-diaminopropionic acid(β-N-ODAP)and its isomer a-N-oxalo-L-α,β-diaminopropionic acid(α-N-ODAP)in Panax ginseng C.A.Meyer(cultivated ih Northeastern China),Panax quinquefolius L.,Panax notoginseng F.H.Chen(cultivated in Southwestern China),Korean red ginseng and Jilin red ginseng were isolated and identified.Efficient separation and purification methods forβ-N-ODAP andα-N-ODAP were developed.展开更多
文摘This paper reports the primary results of the study on β-lactam derivatives of 2,4-diaryl-2, 3-di hydro-1, 5 -benzothiazepines. Five titie compounds have been synthesized, and their configUration and conformation were detendned by X-ray crystallographic analysis.
文摘The modified Hofmann degradation of koumine(1) has proved abortive. The struture and stereochemistry of the main product(3) were deduced by spectral methods and confirmed by X-ray diffration analysis. From the roots of Gelsemium elegans, dihydrokounine was first isolated as a natural product.
基金The project supported by National Natural Science Foundation of China
文摘The neuroexcitotoxic nonprotein amino acidβ-N-oxalo-L-α,β-diaminopropionic acid(β-N-ODAP)and its isomer a-N-oxalo-L-α,β-diaminopropionic acid(α-N-ODAP)in Panax ginseng C.A.Meyer(cultivated ih Northeastern China),Panax quinquefolius L.,Panax notoginseng F.H.Chen(cultivated in Southwestern China),Korean red ginseng and Jilin red ginseng were isolated and identified.Efficient separation and purification methods forβ-N-ODAP andα-N-ODAP were developed.
