Natural product chemistry is an important area across chemistry, biology, and pharmaceutical sciences. The discovery of natural products through isolation and structural elucidation expands the chemical space of biolo...Natural product chemistry is an important area across chemistry, biology, and pharmaceutical sciences. The discovery of natural products through isolation and structural elucidation expands the chemical space of biologically active molecules in an unparallel fashion; numerous medicinally relevant compounds arise from natural product scaffolds. The chemical synthesis of natural products advances the development of organic chemistry from the theoretical, strategic, and methodological perspectives, and provides versatile access to natural product derivatives and mimics with improved pharmacological properties.展开更多
文摘Natural product chemistry is an important area across chemistry, biology, and pharmaceutical sciences. The discovery of natural products through isolation and structural elucidation expands the chemical space of biologically active molecules in an unparallel fashion; numerous medicinally relevant compounds arise from natural product scaffolds. The chemical synthesis of natural products advances the development of organic chemistry from the theoretical, strategic, and methodological perspectives, and provides versatile access to natural product derivatives and mimics with improved pharmacological properties.