BACKGROUND Hypersensitivity pneumonitis(HP)is an immune-mediated syndrome caused by allergen inhalation.High-resolution computed tomography(HRCT)of HP may show diffuse ground-glass opacity,centrilobular ground-glass n...BACKGROUND Hypersensitivity pneumonitis(HP)is an immune-mediated syndrome caused by allergen inhalation.High-resolution computed tomography(HRCT)of HP may show diffuse ground-glass opacity,centrilobular ground-glass nodules,areas of air-trapping,thin-walled cysts,or fibrotic changes.CASE SUMMARY A 47-year-old male patient went to the hospital complaining of cough and gradual aggravation of shortness of breath.HRCT of the lung showed that multiple nodules and ground-glass high-density shadows were present in both lungs.In addition,circular high-density shadows of various sizes were widely distributed in both lungs with relatively normal lung markings inside them.But other tests did not have a positive finding that can clarify the cause.Therefore,the patient underwent a lung biopsy.The pathological results showed that the lesions tended to be HP.After 4 mo of follow-up,the lesions in the patient's lungs were absorbed spontaneously,and the symptoms of cough and shortness of breath have disappeared.The review results suggested that the patient's disease was self-healing,which was consistent with the characteristics of HP.CONCLUSION For some patients with HP,abnormal HRCT findings,such as the lesions in the lungs,can be absorbed on their own,which is an important clue in the diagnosis of the disease.Early diagnosis by lung biopsy is necessary when antigen exposure is unknown.展开更多
To the Editor： In China and neighboring countries, there is increasing health concern over the dust storm fine particulate matter （PM） originating in the Gansu Corridor and Mongolian regions of China. PM is a mixtu...To the Editor： In China and neighboring countries, there is increasing health concern over the dust storm fine particulate matter （PM） originating in the Gansu Corridor and Mongolian regions of China. PM is a mixture of various particles including crustal material, metals, and bioaerosols. Elevated levels of ambient PM were also reported to be associated with increased cardiopulmonary morbidity and mortality.A recent World Health Organization report indicated that exposure to fine PM air pollution and other pollutants caused approximately seven million deaths in 2012 worldwide, while the Global Burden of Disease Study showed that PM exposure was responsible for 2.9 million deaths and 69.7 million disability-adjusted life-years in 2013. Finally, studies showed that reduced PM concentrations were associated with reduced mortality risk.展开更多
基金the Scientific Research Project of Gansu Provincial People's Hospital,No.2019-290。
文摘BACKGROUND Hypersensitivity pneumonitis(HP)is an immune-mediated syndrome caused by allergen inhalation.High-resolution computed tomography(HRCT)of HP may show diffuse ground-glass opacity,centrilobular ground-glass nodules,areas of air-trapping,thin-walled cysts,or fibrotic changes.CASE SUMMARY A 47-year-old male patient went to the hospital complaining of cough and gradual aggravation of shortness of breath.HRCT of the lung showed that multiple nodules and ground-glass high-density shadows were present in both lungs.In addition,circular high-density shadows of various sizes were widely distributed in both lungs with relatively normal lung markings inside them.But other tests did not have a positive finding that can clarify the cause.Therefore,the patient underwent a lung biopsy.The pathological results showed that the lesions tended to be HP.After 4 mo of follow-up,the lesions in the patient's lungs were absorbed spontaneously,and the symptoms of cough and shortness of breath have disappeared.The review results suggested that the patient's disease was self-healing,which was consistent with the characteristics of HP.CONCLUSION For some patients with HP,abnormal HRCT findings,such as the lesions in the lungs,can be absorbed on their own,which is an important clue in the diagnosis of the disease.Early diagnosis by lung biopsy is necessary when antigen exposure is unknown.
基金This study was supported by grants from the National Natural Science Foundation of China （No, 41461020 and No. 41161019）.
文摘To the Editor： In China and neighboring countries, there is increasing health concern over the dust storm fine particulate matter （PM） originating in the Gansu Corridor and Mongolian regions of China. PM is a mixture of various particles including crustal material, metals, and bioaerosols. Elevated levels of ambient PM were also reported to be associated with increased cardiopulmonary morbidity and mortality.A recent World Health Organization report indicated that exposure to fine PM air pollution and other pollutants caused approximately seven million deaths in 2012 worldwide, while the Global Burden of Disease Study showed that PM exposure was responsible for 2.9 million deaths and 69.7 million disability-adjusted life-years in 2013. Finally, studies showed that reduced PM concentrations were associated with reduced mortality risk.
