The BnTFL1–BnGF14nu–BnFD module regulates flower development and plant architecture in Brassica napus

Flower development and plant architecture determine the efficiency of mechanized harvest and seed yield in Brassica napus.Although TERMINAL FLOWER 1(AtTFL1)is a regulator of flower development in Arabidopsis thaliana,the function and regulatory mechanism of TFL1 orthologs in B.napus remains unclear.Six BnTFL1 paralogs in the genome of the B.napus inbred line‘K407’showed steadily increasing expression during vernalization.CRISPR/Cas-induced mutagenesis of up to four BnTFL1 paralogs resulted in early flowering and alteration of plant architecture,whereas seed yield was not altered in BnTFL1 single,double,or triple mutants.Six BnTFL1 paralogs,but not BnaA02.TFL1,showed an additive and conserved effect on regulating flowering time,total and terminal flower number,and plant architecture.BnaA10.TFL1 regulates flower development by interacting with BnaA08.FD through the protein BnaA05.GF14nu,resulting in the transcriptional repression of floral integrator and floral meristem identity genes.These findings about the regulatory network controlling flower development and plant architecture present a promising route to modifying these traits in B.napus.

试论未成年人罪错行为干预体系的分层构建

目前针对未成年人罪错行为的刑事化处理与非刑事化处理呈现'二元分立、发展失衡、衔接断层'的特征,在制度层面和实践层面均存在亟待解决的现实问题。未来改革中,应当充分贯彻'以教代刑'的少年司法理念,以干预介入的及时性和教育矫治的专业性为改革方向,整合制度资源、引入社会力量,强化非刑事化处理措施的保护处分性质,提升刑事处理的行刑社会化水平,探索建立'家庭、学校教育—基地观护—收容教养—刑事处遇'的未成年人罪错社会化干预体系。

宫颈柱状上皮异位与沙眼衣原体、解脲脲原体感染相关性研究

目的:分析宫颈柱状上皮异位与沙眼衣原体感染、解脲脲原体的相关性。方法:将61例宫颈柱状上皮异位患者和60例接受妇科检查的常规体检患者分别设为实验组和对照组,采集两组宫颈分泌物进行沙眼衣原体、解脲脲原体检测。结果:实验组沙眼衣原体、解脲脲原体的阳性检出率均高于对照组(均P<0.05)。实验组中重度宫颈柱状上皮异位患者的沙眼衣原体、解脲脲原体阳性检出率均高于中度宫颈柱状上皮异位患者和轻度宫颈柱状上皮异位患者(均P<0.05)。结论:宫颈柱状上皮异位患者容易发生沙眼衣原体和解脲脲原体感染,且病变程度越严重,沙眼衣原体、解脲脲原体感染的发生率越高。

Design and simulation of fault diagnosis based on NUIO/LMI for satellite attitude control systems

This paper presents a scheme of fault diagnosis for flexible satellites during orbit maneuver. The main contribution of the paper is related to the design of the nonlinear input observer which can avoid false alarm arising from the disturbance from orbit control force. The effects of orbit control force on the fault diagnosis system for satellite attitude control systems, including the disturbing torque caused by the misalignments and the model uncertainty caused by the fuel consumed, are discussed, where standard Lu- enberger observer cannot work well. Then the nonlinear unknown input observer is proposed to decouple faults from disturbance, Besides, a linear matrix inequality approach is adopted to reduce the effect of nonlinear part and model uncertainties on the observer. The numerical and semi-physical simulation demonstrates the effectiveness of the proposed observer for the fault diagnosis system of the satellite during orbit maneuver.

A multifunctional electrolyte with highly-coordinated solvation structure-in-nonsolvent for rechargeable lithium batteries

Rechargeable lithium-based battery is hailed as next-generation high-energy-density battery systems.However, growth of lithium dendrites, shuttle effect of lithium polysulfides intermediates and unstable interphase of high-voltage intercalation-type cathodes largely prevent their practical deployment.Herein, to fully conquer the three challenges via one strategy, a novel electrolyte with highlycoordinated solvation structure-in-nonsolvent is designed. On account of the particular electrolyte structure, the shuttle effect is completely suppressed by quasi-solid conversion of S species in Li-S batteries,with a stable cycle performance even at lean electrolyte(5μL mg^(-1)). Simultaneously, in-situ-formed highly-fluorinated interphases can not only lower Li+diffusion barrier to ensure uniform nucleation of Li but also improve stability of NCM cathodes, which enable excellent capacity retention of Lik LiNi(0.5)Co(0.2)Mn(0.3)O2 batteries under conditions toward practical applications(high loading of 2.7 m Ah cm^(-2) and lean electrolyte of 5 m L Ah^(-1)). Besides, the electrolyte is also nonflammable. This electrolyte structure offers useful guidelines for the design of novel organic electrolytes for practical lithium-based batteries.

A self-healing liquid metal anode for lithium-ion batteries

The gallium-based liquid metal as one of the self-healing materials has gained wide attention, especially in the energy storage system. However, volume expansion with the ‘‘liquid-solid-liquid”transformation process still leads to un-controlled electrode failure, which stimulates the irreversibility of liquid metal and hinders their self-healing effect as the anode for lithium-ion batteries. Herein, the polypyrrole(PPy) with highly conductive and adhesive features is first introduced to fasten the liquid metal nanoparticles(gallium-tin alloy, EGaSn) in the integrated electrode and applied as the anode for lithium-ion batteries. A tightly PPy wrapped EGaSn nanoparticles structure is formed during the in-situ polymerization synthesis process, which effectively avoids the detachment of solid alloyed products. Based on the features of PPy, polyacrylic acid is added to facilitate strengthening the integrity of the electrode by constructing the hydrogen bond. The ‘‘dual-insurance” design endows the EGaSn to exhibit superior electrochemical kinetics and an astonishing self-healing effect. As a result, the customized anode displays superior cycling stability(499.8 mAh g^(-1) after 500 cycles at 1.0 A g^(-1))and rate capability(350 mAh g^(-1) at 2.0 A g^(-1)).This work enriches the electrode engineering technology of liquid metal nanoparticles and opens up a new way to customize the self-healing anode for lithium-ion batteries.

锂金属电池电解液的理论计算模拟研究

锂金属电池电解液的调控对锂枝晶生长抑制具有重要意义。传统的电解液设计思路主要依赖经验直觉与实验试错,较少借助计算模拟方法以高通量筛选电解液配方。理论计算模拟手段能够建立电解液微观特征与宏观性质之间的联系,从原子尺度上指导电解液设计、预测电解液性能,在电解液研究领域发挥了重要作用。本文综述了锂金属电池电解液在理论计算模拟方面的相关进展。首先,介绍了电解液研究中量子化学计算和分子动力学模拟的基本原理与计算方法;其次,总结了这两种计算模拟手段在电解液组分静态化学性质、电解液体相和电极-电解液界面的微观结构与性质研究中的应用,如配位络合物中的结合能,电解液组分的氧化还原稳定性、静电势,体相电解液的溶剂化结构、离子电导率、介电常数,电极-电解液界面的微观结构、性质与化学反应;最后,讨论了理论计算模拟面临的挑战及未来的发展方向,为锂金属电池电解液的计算模拟提供了新的研究思路。

Chitosan/LiCl composite scaffolds promote skin regeneration in full-thickness loss

Small molecules loaded into biological materials present a promising strategy for stimulating endogenous repair mechanisms for in situ skin regeneration.Lithium can modulate various biologic processes,promoting proliferation,angiogenesis,and decreasing inflammation.However,its role in skin repair is rarely reported.In this study,we loaded lithium chloride(LiCl)into the chitosan(CHI)hydrogel and develop a sterile and biocompatible sponge scaffold through freeze-drying.In-vitro assessment demonstrated that the CHI-LiCl composite scaffolds(CLiS)possessed favorable cytocompatibility,swelling and biodegradation.We created full-thickness skin wounds in male C57BL/c mice to evaluate the healing capacity of CLiS.Compared with the wounds of control and CHI scaffold(CS)groups,the wounds in the CLiS-treated group showed reduced inflammation,improved angiogenesis,accelerated re-epithelialization,sustained high expression ofβ-catenin with a small amount of regenerated hair follicles.Therefore,CLiS may be a promising therapeutic dressing for skin wound repair and regeneration.

Uniform-dispersed ZnS quantum dots loading on graphene as a promising anode for potassium-ion batteries

The potassium-ion batteries(PIBs)have become the promising energy storage devices due to their relatively moderate cost and plenteous potassium resources.Whereas,the main drawback of PIBs is unsatisfacto ry electrochemical perfo rmance induced by the larger ionic radius of potassium ion.Herein,we report a well-designed,uniform-dispersed,and morphology-controllable zinc sulfide(ZnS)quantum dots loading on graphene as an anode in the PIBs.The directed uniform dispersion of the in-situ growing ZnS quantum dots(~2.8 nm in size)on graphene can mitigate the volume effect during the insertionextraction process and shorten the migration path of potassium ions.As a result,the battery exhibits superior cycling stability(350.4 mAh/g over 200 cycles at 0.1 A/g)and rate performance(98.8 mAh/g at2.0 A/g).We believe the design of active material with quantum dot-minimized size provides a novel route into PIBs and contributes to eliminating the major electrode failure issues of the system.