In order to study the influence of rubidium(Rb)addition on the phase composition,microstructure,mechanical properties and cell response of bioactive glass-ceramics,CaO−SiO2−Na2O−B2O3−MgO−ZnO−P2O5 glass system was desi...In order to study the influence of rubidium(Rb)addition on the phase composition,microstructure,mechanical properties and cell response of bioactive glass-ceramics,CaO−SiO2−Na2O−B2O3−MgO−ZnO−P2O5 glass system was designed with and without addition of Rb.The results show that hydroxyapatite(HA)and Mg−whitelockite(Ca18Mg2H2(PO4)14)crystalline phases are formed in the glass matrix without Rb.After the addition of Rb,only HA phase is detected.The grain size of the crystals in the glass-ceramics is larger with the addition of Rb than that of samples without Rb.Rb addition can improve the bending strength of glass-ceramics.The cultivation of human bone marrow mesenchymal stem cells(hBMSCs)on Rb-containing glass-ceramics demonstrates enhanced cell adhesion,proliferation and ALP activity.In conclusion,Rb-modified glass-ceramics exhibit good mechanical property,excellent bioactivity and biocompatibility,which have potential for bone regeneration application.展开更多
Ti−Zr alloys(oxygen content 0.42−0.54 wt.%)were prepared via powder metallurgy and hot working.The results indicate that the Ti−Zr alloys exhibit Zr-rich and Zr-lean areas with the sameα-phase structure,and the Zr-ri...Ti−Zr alloys(oxygen content 0.42−0.54 wt.%)were prepared via powder metallurgy and hot working.The results indicate that the Ti−Zr alloys exhibit Zr-rich and Zr-lean areas with the sameα-phase structure,and the Zr-rich area shows a slightly higher oxygen content and a much finer grain size.The Ti−Zr alloys present a good combination of high strength(σs=700−900 MPa)and total elongation(>20%),and solid solution strengthening of oxygen plays a major role.Zr does not influence much the oxygen-induced brittleness due to its high structural similarity to Ti.Therefore,the high value of 0.54 wt.%is still within the critical oxygen content for the ductile-to-brittle transition of Ti and does not degrade the ductility.展开更多
基金The authors are grateful for the financial supports from the Natural Science Foundation of Hunan Province,China(2019JJ50797)the Postdoctoral Science Foundation of China(2019T120711).
文摘In order to study the influence of rubidium(Rb)addition on the phase composition,microstructure,mechanical properties and cell response of bioactive glass-ceramics,CaO−SiO2−Na2O−B2O3−MgO−ZnO−P2O5 glass system was designed with and without addition of Rb.The results show that hydroxyapatite(HA)and Mg−whitelockite(Ca18Mg2H2(PO4)14)crystalline phases are formed in the glass matrix without Rb.After the addition of Rb,only HA phase is detected.The grain size of the crystals in the glass-ceramics is larger with the addition of Rb than that of samples without Rb.Rb addition can improve the bending strength of glass-ceramics.The cultivation of human bone marrow mesenchymal stem cells(hBMSCs)on Rb-containing glass-ceramics demonstrates enhanced cell adhesion,proliferation and ALP activity.In conclusion,Rb-modified glass-ceramics exhibit good mechanical property,excellent bioactivity and biocompatibility,which have potential for bone regeneration application.
基金Project(51625404)supported by the National Natural Science Foundation for Distinguished Young Scholar of China。
文摘Ti−Zr alloys(oxygen content 0.42−0.54 wt.%)were prepared via powder metallurgy and hot working.The results indicate that the Ti−Zr alloys exhibit Zr-rich and Zr-lean areas with the sameα-phase structure,and the Zr-rich area shows a slightly higher oxygen content and a much finer grain size.The Ti−Zr alloys present a good combination of high strength(σs=700−900 MPa)and total elongation(>20%),and solid solution strengthening of oxygen plays a major role.Zr does not influence much the oxygen-induced brittleness due to its high structural similarity to Ti.Therefore,the high value of 0.54 wt.%is still within the critical oxygen content for the ductile-to-brittle transition of Ti and does not degrade the ductility.
