Dear Editor,Arabidopsis thaliana is an important model organism in plant biology and genetics.The genome of Arabidopsis ecotype Columbia-0 has been sequenced and completely annotated(Cheng et al.,2017),which facilitat...Dear Editor,Arabidopsis thaliana is an important model organism in plant biology and genetics.The genome of Arabidopsis ecotype Columbia-0 has been sequenced and completely annotated(Cheng et al.,2017),which facilitates the genomics research of plants.Over the past two decades,advances in the gene regulation studies have elucidated a spectrum of epigenetic molecular phenomena,including DNA methylation,histone modification,chromatin accessibility,and chromatin interaction,which collectively form an additional layer of information based on DNA sequence(Law and Jacobsen,2010).The epigenome landscape has been characterized in Arabidopsis as more high-throughput analyses were developed(Zhao et al.,2022).Without a doubt,in-depth studies of gene expression regulation heavily rely on such epigenomic information.However,the utilization of this knowledge poses a challenge for certain groups lacking bioinformatics analysts or adequate computing resources.展开更多
基金the Fundamental Research Funds for the Central Universities(2662021PY005 and 2662023PY002 to G.L.).
文摘Dear Editor,Arabidopsis thaliana is an important model organism in plant biology and genetics.The genome of Arabidopsis ecotype Columbia-0 has been sequenced and completely annotated(Cheng et al.,2017),which facilitates the genomics research of plants.Over the past two decades,advances in the gene regulation studies have elucidated a spectrum of epigenetic molecular phenomena,including DNA methylation,histone modification,chromatin accessibility,and chromatin interaction,which collectively form an additional layer of information based on DNA sequence(Law and Jacobsen,2010).The epigenome landscape has been characterized in Arabidopsis as more high-throughput analyses were developed(Zhao et al.,2022).Without a doubt,in-depth studies of gene expression regulation heavily rely on such epigenomic information.However,the utilization of this knowledge poses a challenge for certain groups lacking bioinformatics analysts or adequate computing resources.
