Long-range olefin isomerization could lead to the remote functionalization of hydrocarbon chains,which is advantageous with regards to atom-,step-,and redox economy.However,present methodologies for long-range olefin ...Long-range olefin isomerization could lead to the remote functionalization of hydrocarbon chains,which is advantageous with regards to atom-,step-,and redox economy.However,present methodologies for long-range olefin isomerization are mainly focused on heteroatom directed remote olefin migration;studies using aryl groups as the directing group are limited.The limited examples either utilize aryl olefins with special substituted groups on a benzene ring,or use elaborately optimized ligands or co-catalysts to accelerate the isomerization.A more simple catalytic system for general aryl olefins,without the need for special ligands or co-catalysts,was to be developed.Herein,we report a Pd-catalyzed long-range olefin isomerization(up to 15 units)for general aryl olefins via a 1,2-hydrogen shift mechanism.This methodology provides a simple pathway to long-range olefin isomerization without the participation of special ligands or co-catalysts.展开更多
基金We would like to thank the Research Foundation of Education Bureau of Hunan Province(No.19K079)the National Key R&D Program of China(No.2018YFE0126800)for financial support.We thank the Instrumental Analysis Center of SJTU for characterza-tion.
文摘Long-range olefin isomerization could lead to the remote functionalization of hydrocarbon chains,which is advantageous with regards to atom-,step-,and redox economy.However,present methodologies for long-range olefin isomerization are mainly focused on heteroatom directed remote olefin migration;studies using aryl groups as the directing group are limited.The limited examples either utilize aryl olefins with special substituted groups on a benzene ring,or use elaborately optimized ligands or co-catalysts to accelerate the isomerization.A more simple catalytic system for general aryl olefins,without the need for special ligands or co-catalysts,was to be developed.Herein,we report a Pd-catalyzed long-range olefin isomerization(up to 15 units)for general aryl olefins via a 1,2-hydrogen shift mechanism.This methodology provides a simple pathway to long-range olefin isomerization without the participation of special ligands or co-catalysts.
