Inquiry of Water-Soluble Polysaccharide Extraction Conditions from Grapefruit Skin

Water-soluble polysaccharide was isolated from grapefruit with the method of water-dissolving and ethanol-precipitating. By single factor test and orthogonal experimental method, the extraction conditions of the water-soluble polysaccharide were investigated, which contained liquid-solid ratio, temperature, time and pH. The results showed that pH was the most important factor of polysaccharide extraction, followed by temperature. The optimized extraction technology conditions were obtained. The liquid-solid ratio was 1:40, temperature was 90?C, time was 2.0 h, and pH was 2. The highest extraction rate of crude polysaccharide was 8.30%.

穿支皮瓣在面部恶性肿瘤切除术后创面美容性修复中的应用

目的探讨穿支皮瓣在面部恶性肿瘤切除术后创面美容性修复中的临床应用价值。方法回顾性描述性研究。纳入2016年2月—2021年2月在成都医学院第二附属医院、溧阳市人民医院整形外科面部恶性肿瘤切除术后面部缺损患者50例,其中男20例、女30例,年龄38~95岁。肿瘤切除后,面部皮肤缺损1.5 cm×1.5 cm~3.5 cm×7.5 cm。根据患者恶性肿瘤切除术后面部缺损的大小、位置与形状,设计推进、旋转、螺旋桨等多种面部穿支皮瓣进行创面修复。皮瓣面积1.5 cm×1.0 cm~ 12.0 cm×6.0 cm;蒂部穿支血管直径在0.3~3.0 mm,其中2例蒂部为穿支血管束。术后观察皮瓣存活情况,同时对并发症予以对症处理;术后对皮瓣色泽、修复后功能、美观度及复发情况进行随访,评价其创面修复效果。结果本组50例手术均顺利完成。术后49例皮瓣一期愈合;1例术后皮瓣淤血,予针刺放血、局部按摩治疗,1周后好转,伤口延迟愈合。供区切口均一期愈合。术后随访3 ~24个月,皮瓣的质地、颜色和触感与周围皮肤相一致,供区瘢痕不明显,50例患者对术后皮瓣供区与受区功能及外形均满意。结论采用穿支皮瓣对面部恶性肿瘤切除后面部缺损进行修复,是一种安全、可靠的修复方式,对面部恶性肿瘤切除术后创面的美容性修复具有一定的临床价值。