Clinical Observation on the Treatment of Diabetic Kidney Disease with Damp-heat Stasis Syndrome in Clinical Proteinuria Stage by Kunkui Kidney Preserving Paste

[Objectives]To evaluate the clinical efficacy and safety of Kunkui Kidney Preserving Paste in the treatment of diabetic kidney disease(DKD)patients with damp-heat stasis syndrome in the clinical proteinuria stage.[Methods]Retrospective analysis was made on 30 patients with DKD who were diagnosed with damp-heat stasis syndrome in the clinical proteinuria stage from March 2021 to March 2023 in Jiangsu Province Hospital of Chinese Medicine,and who took Kunkui Kidney Preserving Paste continuously for six months.The urinary albumin/creatinine ratio(UACR),urinary complement C3,and urea nitrogen(BUN)of DKD patients before and after treatment were compared,and estimated glomerular filtration rate(eGFR),blood creatinine(Scr),and cystatin C(CysC)were estimated,and the therapeutic effects on renal function and urinary protein were evaluated.[Results]After treatment,UACR significantly decreased(P<0.01),and urinary complement C3 and Scr decreased(P<0.05),while other indicators showed no significant statistical difference(P>0.05).In terms of evaluating the efficacy of urinary protein therapy,8 cases showed recent relief;8 cases showed significant effect;9 cases were effective,and 5 cases were invalid after treatment,with a total effective rate of 83.33%.In terms of renal function efficacy evaluation,8 cases showed significant effect;4 cases were effective;11 cases were stable,and 7 cases were invalid,with a total effective rate of 76.67%.In the safety evaluation,there were no obvious adverse reactions.[Conclusions]The Kunkui Kidney Preserving Past has significant clinical efficacy and safety in treating DKD patients with damp-heat stasis syndrome in the clinical proteinuria period.It has significant advantages in reducing urinary protein and protecting renal function,which is worthy of clinical promotion.

Geometrical Design and Hydraulic Feasibility of Inner-Reinforced Girders in Hydropower Bifurcations

Inner-reinforced girders, also known as ribs, are widely used in hydropower bifurcations. However, while they strengthen structures, they also cause energy loss. This work aims to develop an appropriate geometry form for ribs that can diminish head loss in hydropower bifurcations. The term rib/breadth ratio(RBR) is defined to describe the geometrical form of ribs. An investigation is conducted to study the flow and performance characteristics of bifurcations with ribs using computational fluid dynamics. The dependence of the head loss coefficient on the RBR is given in six working conditions. Results show that the ribs change the local flow patterns and slightly increase the water head loss in some cases. In other cases,however, the ribs make the flow smooth. An appropriate RBR is the key to improve the flow patterns in hydropower bifurcations. The head loss varies with the RBR and reaches the minimum when the RBR is 0.3.

韶关市2016年至2019年院前急救疾病谱及其流行病学现况研究

院前急救是急救医疗服务体系(emergency medical service system,EMSS)的重要组成部分,不仅可以反映国家对急救工作的重视程度,还可在一定程度上决定抢救成功率[1]。了解掌握院前急救疾病谱及其流行病学分布特征,有利于科学合理优化急救医疗资源,提高院前医疗急救质量和救治水平,为制定院前急救工作规划、有针对性地加强院前专业队伍规范化培训提供科学参考依据。笔者对韶关市2016年至2019年"120"指挥中心数据库所有接警受理的呼救电话资料进行了回顾性调查。现将调查结果报告如下。