In the near future,single-molecule surface-enhanced Raman spectroscopy(SERS)is expected to expand the family of popular analytical tools for single-molecule characterization.We provide a roadmap for achieving single m...In the near future,single-molecule surface-enhanced Raman spectroscopy(SERS)is expected to expand the family of popular analytical tools for single-molecule characterization.We provide a roadmap for achieving single molecule SERS through different enhancement strategies for diverse applications.We introduce some characteristic features related to single-molecule SERS,such as Raman enhancement factor,intensity fluctuation,and data analysis.We then review recent strategies for enhancing the Raman signal intensities of single molecules,including electromagnetic enhancement,chemical enhancement,and resonance enhancement strategies.To demonstrate the utility of single-molecule SERS in practical applications,we present several examples of its use in various fields,including catalysis,imaging,and nanoelectronics.Finally,we specify current challenges in the development of single-molecule SERS and propose corresponding solutions.展开更多
基金This work was supported by the National Natural Science Foundation of China(Nos.11434017 and 11804254)Guangdong Innovative and Entrepreneurial Research Team Program(No.2016ZT06C594)+8 种基金National Key R&D Program of China(No.2018YFA 0306200)Science and Technology Projects of Jiangmen[Nos.(2017)307 and 149]Program for Innovative Research Team of Jiangmen[No.(2017)385]Science and Technology Projects of Guangdong Province(No.2016A020225009)Program for Key Basic Research of Guangdong(No.2017KZDXM083)Cooperative Education Platform of Guangdong Province[No.(2016)31]Innovative Research Team in University of Guangdong(No.2015KCXTD027)Key Laboratory of Optoelectronic Materials and Applications in Guangdong Higher Education(No.2017KSYS011)2014 Leap Project Center of Education Department Key Platform Construction in Guangdong Province(No.GCZX-A1411).
文摘In the near future,single-molecule surface-enhanced Raman spectroscopy(SERS)is expected to expand the family of popular analytical tools for single-molecule characterization.We provide a roadmap for achieving single molecule SERS through different enhancement strategies for diverse applications.We introduce some characteristic features related to single-molecule SERS,such as Raman enhancement factor,intensity fluctuation,and data analysis.We then review recent strategies for enhancing the Raman signal intensities of single molecules,including electromagnetic enhancement,chemical enhancement,and resonance enhancement strategies.To demonstrate the utility of single-molecule SERS in practical applications,we present several examples of its use in various fields,including catalysis,imaging,and nanoelectronics.Finally,we specify current challenges in the development of single-molecule SERS and propose corresponding solutions.
