Divalent metal clusters have received great attention due to the interesting size-induced nonmetal-to-metal transition and fascinating properties dependent on cluster size,shape,and doping.In this work,the combination...Divalent metal clusters have received great attention due to the interesting size-induced nonmetal-to-metal transition and fascinating properties dependent on cluster size,shape,and doping.In this work,the combination of the CALYPSO code and density functional theory(DFT)optimization is employed to explore the structural properties of neutral and anionic Mg_(n+1) and SrMgn(n=2-12)clusters.The results exhibit that as the atomic number of Mg increases,Sr atoms are more likely to replace Mg atoms located in the skeleton convex cap.By analyzing the binding energy,second-order energy difference and the charge transfer,it can be found the SrMg9 cluster with tower framework presents outstanding stability in a studied size range.Further,bonding characteristic analysis reveals that the stability of SrMg9 can be improved due to the strong s-p interaction among the atomic orbitals of Sr and Mg atoms.展开更多
The Gaussian beam migration(GBM) is a steady imaging approach, which has high accuracy and efficiency. Its implementation mainly includes the traditional frequency domain and the recent popular space-time domain. Firs...The Gaussian beam migration(GBM) is a steady imaging approach, which has high accuracy and efficiency. Its implementation mainly includes the traditional frequency domain and the recent popular space-time domain. Firstly, we use the upward ray tracing strategy to get the backward wavefields. Then,we use the dominant frequency of the seismic data to simplify the imaginary traveltime calculation of the wavefields, which can cut down the Fourier transform number compared with the traditional GBM in the space-time domain. In addition, we choose an optimized parameter for the take-off angle increment of the up-going and down-going rays. These optimizations help us get an efficient space-time-domain acoustic GBM approach. Typical four examples show that the proposed method can significantly improve the computational efficiency up to one or even two orders of magnitude in different models with different model parameters and produce good imaging results with comparable accuracy and resolution with the traditional GBM in the space-time domain.展开更多
To the Editor:Palmoplantar pustulosis(PPP)is a chronic recalcitrant disease.Various biologics have been used to successfully treat plaque psoriasis,but their use to treat PPP is limited.Despite their promising effects...To the Editor:Palmoplantar pustulosis(PPP)is a chronic recalcitrant disease.Various biologics have been used to successfully treat plaque psoriasis,but their use to treat PPP is limited.Despite their promising effects,biologics such as tumor necrosis factor-α(TNF-α)inhibitors may aggravate or induce PPP.Herein,we report a patient with PPP refractory to the TNF-αinhibitor adalimumab,but successfully treated with the interleukin-17A(IL-17A)inhibitor secukinumab.展开更多
基金supported by the National Key Research and Development Program of China (No. 2018YFB2002000)the Guangdong Basic and Applied Basic Research Foundation,China (Nos. 2021A515012271, 2019A1515011220, 2020B1515120027)
基金the National Natural Science Foundation of China(Grant No.11404008)the Artificial Intelligence Key Laboratory of Sichuan Province,China(Grant No.2018RYJ07)+2 种基金the Innovation Fund of Postgraduate Sichuan University of Science&Engineering,China(Grant Nos.y202007 and y2021008)the Innovation and Entrepreneurship Training Program of Sichuan Province,China(Grant Nos.S202010622080 and S202010622082)the Innovation and Entrepreneurship Training Program of Sichuan University of Science&Engineering,China(Grant No.cx2019005)。
文摘Divalent metal clusters have received great attention due to the interesting size-induced nonmetal-to-metal transition and fascinating properties dependent on cluster size,shape,and doping.In this work,the combination of the CALYPSO code and density functional theory(DFT)optimization is employed to explore the structural properties of neutral and anionic Mg_(n+1) and SrMgn(n=2-12)clusters.The results exhibit that as the atomic number of Mg increases,Sr atoms are more likely to replace Mg atoms located in the skeleton convex cap.By analyzing the binding energy,second-order energy difference and the charge transfer,it can be found the SrMg9 cluster with tower framework presents outstanding stability in a studied size range.Further,bonding characteristic analysis reveals that the stability of SrMg9 can be improved due to the strong s-p interaction among the atomic orbitals of Sr and Mg atoms.
基金jointly supported by the National Key Research and Development Program of China (2019YFC0605503)the National Natural Science Foundation of China (41821002, 41922028,41874149)+1 种基金the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA14010303)the Major Scientific and Technological Projects of CNPC (ZD2019-183-003)。
文摘The Gaussian beam migration(GBM) is a steady imaging approach, which has high accuracy and efficiency. Its implementation mainly includes the traditional frequency domain and the recent popular space-time domain. Firstly, we use the upward ray tracing strategy to get the backward wavefields. Then,we use the dominant frequency of the seismic data to simplify the imaginary traveltime calculation of the wavefields, which can cut down the Fourier transform number compared with the traditional GBM in the space-time domain. In addition, we choose an optimized parameter for the take-off angle increment of the up-going and down-going rays. These optimizations help us get an efficient space-time-domain acoustic GBM approach. Typical four examples show that the proposed method can significantly improve the computational efficiency up to one or even two orders of magnitude in different models with different model parameters and produce good imaging results with comparable accuracy and resolution with the traditional GBM in the space-time domain.
基金National Natural Science Foundation of China(No.81872518)。
文摘To the Editor:Palmoplantar pustulosis(PPP)is a chronic recalcitrant disease.Various biologics have been used to successfully treat plaque psoriasis,but their use to treat PPP is limited.Despite their promising effects,biologics such as tumor necrosis factor-α(TNF-α)inhibitors may aggravate or induce PPP.Herein,we report a patient with PPP refractory to the TNF-αinhibitor adalimumab,but successfully treated with the interleukin-17A(IL-17A)inhibitor secukinumab.
