Toxoplasma gondii is a widespread parasite that may infect nearly all warm-blooded vertebrates.1 As an obligatory intracellular apicomplexan parasite,T.gondii has three different types of secretory organelles,includin...Toxoplasma gondii is a widespread parasite that may infect nearly all warm-blooded vertebrates.1 As an obligatory intracellular apicomplexan parasite,T.gondii has three different types of secretory organelles,including micronemes,rhoptries(ROP),and dense granules(GRAs),during invasion of host cells.2 Initially,the parasite replicates in a variety of host cell types as tachyzoites,especially in macrophages and dendritic cells(DCs).展开更多
基金The work was funded by the Natural Science Foundation of China(Y.C.,Grant no.81572801 and L.Y.,Grant no.81572022)the Postdoctoral Foundation of Anhui Province(Y.C.,Grant no.2017B160).
文摘Toxoplasma gondii is a widespread parasite that may infect nearly all warm-blooded vertebrates.1 As an obligatory intracellular apicomplexan parasite,T.gondii has three different types of secretory organelles,including micronemes,rhoptries(ROP),and dense granules(GRAs),during invasion of host cells.2 Initially,the parasite replicates in a variety of host cell types as tachyzoites,especially in macrophages and dendritic cells(DCs).