Genetic Diversity and Genetic Structure of Maize Inbred Lines from Yunnan Revealed by SNP Chips

[Objectives]The genetic diversity and population genetic structure of 107 inbred lines of maize in Yunnan were analyzed,in order to provide technical support for maize germplasm innovation,genetic improvement of germplasm resources,variety management,and lay a solid foundation for exploring genes related to fine traits in the future.[Methods]The 107 maize inbred lines generalized in Yunnan were selected,and 45 backbone inbred lines commonly used in China were used as reference for heterotic group classification.On Axiom Maize 56K SNP Array platform,maize SNP chips(56K)were used to scan the whole maize genome,and the NJ-tree model of Treebest was used to construct a phylogenetic tree.Principal component analysis(PCA)was conducted by GCTA(genome-wide complex trait analysis)to reveal the genetic diversity and population genetic structure.[Results]In the 107 Yunnan local inbred lines,5533 uniformly distributed high-quality SNP marker sites were finally detected.Based on the analysis of these SNP marker sites,Nei s gene diversity index(H)of 107 maize germplasm genes was 0.2981-0.5000 with an average value being 0.4832,and polymorphism information content(PIC)values were 0.2536-0.3750 with an average value being 0.3662.The minimum allele frequency value was 0.5000-0.8178 with an average value being 0.5744.The analysis of population genetic structure showed that when K=6,the maximum value of△K was the maximum,which meant that the inbred lines used in this study could be divided into six groups.They were Tangsi Pingtou blood relationship group,PB blood relationship group,335 female blood relationship group,Zi 330 and the Lüda Honggu blood relationship group,unknown group 1 and unknown group 2.No inbred lines were divided into other heterotic groups.Among them,37 inbred lines from the 2 unknown groups could not be classified into the same group as the 10 known heterotic groups in China.The results of principal component analysis showed that the 107 maize inbred lines generalized in Yunnan could be clearly distinguished from the backbone maize inbred lines commonly used in China.Most of the maize inbred lines in Yunnan were concentrated near the reference backbone inbred lines.But some Yunnan inbred lines were far away from the reference inbred lines commonly used in China.[Conclusions]The maize germplasm resources in Yunnan area were rich in genetic diversity,including multiple heterotic groups,and there was a rich genetic basis of breeding parents.They could be clearly distinguished from the backbone inbred lines commonly used in China,and some of them had a long genetic distance from the backbone inbred lines.The resources which have good application potential can be used to create new heterotic groups.

Characters Selection and Assessment for Spathiphyllum DUS Testing Guideline

[Objectives]This study was conducted to provide technical standards for domestic Spathiphyllum variety description and resource evaluation.[Methods]Through field trials and character surveys of the collected 83 Spathiphyllum varieties,after several revisions by fellow experts,and with reference to the Guidelines for Testing the Specificity,Consistency and Stability of New Plant Varieties:Spathiphyllum(TG/135/3)issued by the International Union For The Protection of New Varieties of Plants,the DUS testing guidelines for Spathiphyllum have been developed,and statistical analysis and other methods were used to study the traits for the guideline.[Results]Thirty two testing traits,including 11 mandatory traits,8 basic traits,10 new traits,and 3 optional traits were finally determined;five traits including plant height,plant width,and leaf length were divided into 7 grades,and 9 traits such as leaf width,spathe length,and spathe width were divided into 5 levels;and the observation method and trait code of the trait spathe depth were adjusted.[Conclusions]The development of this guideline provides a basis for judging the specificity,consistency and stability of Spathiphyllum varieties,and is of great significance to the breeding and protection of Spathiphyllum varieties.

Mobile health applications for the care of patients with breast cancer:A scoping review

Objectives:In recent years,the use of mobile health applications(mHealth apps)to deliver care for patients with breast cancer has increased exponentially.This study aimed to summarize the available evidence on developing mHealth apps to care for patients with breast cancer and identify the need for systematic efforts.Methods:A scoping review was performed according to Arksey and O’Malley’s framework,aiming to identify eligible research studies in PubMed,CINAHL,and Web of Science between January 2010 and December 2020.All identified studies were screened,extracted,and analyzed independently by two reviewers.Results:A total of 676 studies were retrieved,and eight eligible studies were finally included.Four themes emerged:the involvement of patients and health professionals in the phases of design and development,patients’preferences,the characteristics of patients,and the motivators to use mHealth apps.The results indicated promising prospects for using mHealth apps to care for patients with breast cancer and identified the need for systematic efforts to develop and validate relevant apps.Conclusions:The attributes of patient characteristics,needs,and patient-reported outcomes data are vital components for developing mHealth apps for patients with breast cancer.Additionally,collaborative efforts,including patients,nurses,and other significant health professionals,should develop mHealth apps for breast cancer care.Additional research focusing on the design and development of mHealth apps for patients with breast cancer is warranted.

Symptom trajectories in patients with breast cancer:An integrative review

Objective This study aimed to synthesize the available knowledge of symptom trajectories in patients with breast cancer and identify predictors associated with these trajectories.Methods Whittemore and Knafl’s integrative review method was employed to guide a systematic search for literature in four databases(PubMed,Embase,Web of Science,and CINAHL).The retrieved articles’publication time was limited to 2010 to 2020,and only peer-reviewed English articles were included.Results Twenty-seven articles were included.The findings of the relevant studies were analyzed using thematic analysis.They were grouped into two themes:symptom trajectories of patients with breast cancer(symptom trajectories in patients with breast cancer,in patients who underwent surgery,and in patients who received cancer-related treatment)and associated factors(socioeconomic factors,health characteristics,cancer-related treatment characteristics).Newly diagnosed patients tended to report high trajectories of depression and persistent sleep disturbance.Most patients who underwent surgery reported significant sleep disturbance and anxiety shortly after surgery.For patients who received cancer-related treatment,only a small proportion had a high level of physical activity after cancer-related therapy over time.A high body mass index,a low relationship quality,parental responsibilities,insufficient social support,a low educational background,and an unhealthy lifestyle may increase the risk of negative symptom trajectories in patients with breast cancer.Additionally,old patients were more likely to report cognitive impairment after chemotherapy,while young patients tended to report trajectories of persistent sexual dysfunction.Concurring symptoms and poor health status also contributed to adverse symptom trajectories.Conclusion The findings of this review add to the body of knowledge of the interindividual variability of symptom trajectories in patients with breast cancer.Despite the overall similarity in appraisal at baseline,the patients reported varied symptom trajectories over time.It is recommended that nurses consider sociodemographic,clinical and cancer-related treatment characteristics and perform targeted early preventive interventions for patients with breast cancer.

广西北部湾海洋经济、社会与生态系统耦合协调度研究

近年来,广西加速发展海洋经济,不断推动海洋社会发展,同时又要保护海洋生态环境。因此,研究广西海洋经济、社会与生态系统耦合协调发展具有重要的现实意义。本文基于2005~2021年广西北部湾经济区北海、钦州、防城港的海洋经济、社会和生态环境相关面板数据,首先,构建了广西海洋经济、社会和生态环境三系统的综合评价指标体系,采用熵值法和TOPSIS法得到其综合评价指数。在此基础上,利用耦合协调度模型对广西北部湾海洋经济、社会和生态系统的耦合协调发展进行实证研究。结果发现:广西北部湾海洋经济、社会与生态系统综合评价指数总体上逐年增加,广西北部湾海洋经济、社会和生态系统两两之间及三者之间耦合协调水平均由低中度协调发展为良好协调。最后,提出了一些政策性建议。

Associations Between Specific Diets, Dietary Diversity, and Cognitive Frailty in Older Adults — China, 2002–2018

Summary What is already known about this topic?The relationship between specific dietary patterns and dietary diversity with cognitive frailty continues to be a subject of ambiguity.What is added by this report?This research revealed that regular consumption of fruit,meat,bean products,garlic,and tea was connected to a decreased risk of cognitive frailty.Compared to participants with dietary diversity score(DDS)≤6 points,those with DDS of 9–10,11–12,and≥12 had a lower risk of cognitive frailty.