An Overview of Interactive Immersive Services

Immersive services are the typical emerging services in current IMT-2020 network.With the development of network evolution,real-time interactive applications emerge one after another.This article provides an overview on immersive services which focus on real-time interaction.The scenarios,framework,requirements,key technologies,and issues of interactive immersive service are presented.

A novel fast classification filtering algorithm for LiDAR point clouds based on small grid density clustering

Clustering filtering is usually a practical method for light detection and ranging(LiDAR)point clouds filtering according to their characteristic attributes.However,the amount of point cloud data is extremely large in practice,making it impossible to cluster point clouds data directly,and the filtering error is also too large.Moreover,many existing filtering algorithms have poor classification results in discontinuous terrain.This article proposes a new fast classification filtering algorithm based on density clustering,which can solve the problem of point clouds classification in discontinuous terrain.Based on the spatial density of LiDAR point clouds,also the features of the ground object point clouds and the terrain point clouds,the point clouds are clustered firstly by their elevations,and then the plane point clouds are selected.Thus the number of samples and feature dimensions of data are reduced.Using the DBSCAN clustering filtering method,the original point clouds are finally divided into noise point clouds,ground object point clouds,and terrain point clouds.The experiment uses 15 sets of data samples provided by the International Society for Photogrammetry and Remote Sensing(ISPRS),and the results of the proposed algorithm are compared with the other eight classical filtering algorithms.Quantitative and qualitative analysis shows that the proposed algorithm has good applicability in urban areas and rural areas,and is significantly better than other classic filtering algorithms in discontinuous terrain,with a total error of about 10%.The results show that the proposed method is feasible and can be used in different terrains.

Experimental study on vortex induced vibration(VIV) of a wide-D-section cylinder in a cross flow

Wake structures and vortex induced vibration （VIV） of a spring-supported wide-D-section cylinder were experimentally investigated using an X-wire, a novel phase-locked particle image velocimetry （PIV）, and an acceleration sensor at a low speed wind tunnel. Compared with the fixed case, the 2P （two pair） vortex mode as defined by Govardhan and Williamson （2000） rather than S （single vortex） mode exists in the wake. The velocity deficit behind the cylinder is much larger than that of fixed case. The mean drag coefficient increases from 1.42 for the fixed case to 1.64 for the vibrating case. The Reynolds stress presents even distribution and small with increased distance of X/D = -2 to X/D = -10. The power spectra density based on accelerator and hot wire data presents a highlight identical. It shows that after a strong interaction the cylinder vibration and the vortex shedding come to a stable state. The vortex sheddin~ is totally locked on and controlled by the cylinder vihratinn.

Hankel norm of polytopic systems with time-varying delay

This paper addresses the Hankel norm of polytopic systems with time-varying delay. Delay-dependent sufficient conditions are presented such that the polytopic system is stable and the Hankel norm of the polytopic system is less than a prescribed scalar in terms of linear matrix inequalities. A numerical example is presented.

Message for the Special Issue of Advanced Supercritical CO_(2) Power Cycles

Supercritical carbon dioxide(SCO_(2))power cycles,which uses CO_(2) as the working medium to realize thermal power conversion and output electric energy,was first proposed in the 1950s,but has not attracted widespread attention.At the beginning of this century,with the urgent need to reduce greenhouse gas emission and slow down the global warming trend,SCO_(2) power generation started to attract extensive interest.Compared to traditional water steam Rankine cycles,the SCO_(2) Brayton cycles have higher efficiency,more compact system to allow quick response to load variations,and better safety.

Neddylation is required for herpes simplex virus type I （HSV- 1）-induced early phase interferon-beta production

Type I interferons such as interferon-beta （IFN-β） play essential roles in the host innate immune response to herpes simplex virus type I （HSV-1） infection. The transcription of type I interferon genes is controlled by nuclear factor-κB （NF-κB） and interferon regulatory factor （IRF） family members including IRF3. NF-κB activation depends on the phosphorylation of inhibitor of κB （IκB）, which triggers its ubiqitination and degradation. It has been reported that neddylation inhibition by a pharmacological agent MLN4924 potently suppresses lipopolysaccharide （LPS）-induced proinflammatory cytokine production with the accumulation of phosphorylated IκBa. However, the role of neddylation in type I interferon expression remains unknown. Here, we report that neddylation inhibition with MLN4924 or upon UBA3 deficiency led to accumulation of phosphorylated IκBa, impaired IκBa degradation, and impaired NF-κB nuclear translocation in the early phase of HSV-1 infection even though phosphorylation and nuclear translocation of IRF3 were not affected. The blockade of NF-κB nuclear translocation by neddylation inhibition becomes less efficient at the later time points of HSV-1 infection. Consequently, HSV- 1-induced early phase IFN-β production significantly decreased upon MLN4924 treatment and UBA3 deficiency. NF-κB inhibitor JSH-23 mimicked the effects of neddylation inhibition in the early phase of HSV-1 infection. Moreover, the effects of neddylation inhibition on HSV-1-induced early phase IFN-c production diminished in the presence of NF-κB inhibitor JSH-23. Thus, neddylation contributes to HSV-l-induced early phase IFN-β production through, at least partially, promoting NF-κB activation.

Characterization of a Novel Anti-DR5 Monoclonal Antibody WD1 with the Potential to Induce Tumor Cell Apoptosis

TNF-related apoptosis-inducing ligand （TRAIL） is a TNF family member capable of inducing apoptosis. Death receptor 5 （DR 5） is a key receptor of TRAIL and plays an important role in TRAIL-induced apoptosis. To prepare monoclonal antibodies （mAbs） against DR5, cDNA encoding soluble DR5 （sDR5） was firstly amplified by reverse transcriptase-polymerase chain reaction （RT-PCR） with specific primers, and then inserted into a prokaryotic expression vector pET-30a. The recombinant plasmid was expressed in Escherichia coli strain BL21 （DE3）, and sDR5 was purified by nickel affinity chromatography. As an antigen, sDR5 was used to immunize mice. Hybridomas secreting antibodies against sDR5 were identified. One positive done was selected to produce antibody, WD1. ELISA and immunofluorescence demonstrated that WD1 could bind recombinant sDR5 and membranebound DR5 （mDR5） on Jurkat and Molt-4 cells. ATPLite assays showed that Jurkat and Molt-4 cells were sensitive to the antibody in a dose dependent manner. The Annexin V/PI assays and Giemsa＇s staining both showed that WD1 could induce Jurkat cell apoptosis efficiently. Transient transfection of 293T cells and indirect immunofluorescence assay demonstrated that mAb （WD1） couldn＇t cross-react with DR4. Our findings indicated that the novel antibody, WD1 could act as a direct agonist, bind DR5 characteristically, and initiate efficient apoptotic signaling and tumor regression. Thus, WD1 would be a leading candidate for potential cancer therapeutics. Cellular ＆ Molecular Immunology.

Hilbert-Schmidt-Hankel norm model reduction for matrix second-order linear systems

This paper considers the optimal model reduction problem of matrix second-order linear systems in the sense of Hilbert-Schmidt-Hankel norm, with the reduced order systems preserving the structure of the original systems. The expressions of the error function and its gradient are derived. Two numerical examples are given to illustrate the presented model reduction technique.

Highly Efficient Electroluminescent Materials with High Color Purity Based on Strong Acceptor Attachment onto B-N-Containing Multiple Resonance Frameworks

The development and enrichment of organic materials with narrowband emission in longer wavelength regions beyond 515 nm still remains a great challenge.Herein,a synthetic methodology for narrowband emission materials has been proposed to functionalize multiple resonance(MR)skeletons and generate a universal building block,namely,the key intermediate DtCzB-Bpin,which can be utilized to construct multifarious thermally activated delayed fluorescence(TADF)materials with high color purity through a simple one-step Suzuki coupling reaction.Based on this unique synthetic strategy,a series of efficient narrowband green TADF emitters has been constructed by localized attachment of 1,3,5-triazine and pyrimidine derivatives-based acceptors onto B–N-containing MR frameworks with 1,3-bis(3,6-di-tertbutylcarbazol-9-yl)benzene(DtCz)as the ligand.The precise modulation of the acceptor is an intelligent approach to achieve bathochromic shift and narrowband emission simultaneously.The DtCzB-TPTRZbased organic light-emitting diode(OLED)exhibits pure green emission with Commission Internationale de L’Eclairage(CIE)coordinates of(0.23,0.68),a maximum external quantum efficiency(EQE)of 30.6%,and relatively low efficiency roll-off.