Kawasaki disease(KD) is an acute and self-limited febrile disease characterized by fever, polymorphic rash, bulbar conjunctival congestion, redness of the lip mucosa, unilateral cervical lymphadenopathy, erythema, and...Kawasaki disease(KD) is an acute and self-limited febrile disease characterized by fever, polymorphic rash, bulbar conjunctival congestion, redness of the lip mucosa, unilateral cervical lymphadenopathy, erythema, and edema of the extremities. KD was reported first by Tomisaku Kawasaki, a Japanese scholar, in 1967[1]. Since then, the disease has been reported worldwide, with significant differences observed in its incidence in different regions.展开更多
Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of eme...Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up.展开更多
Importance:Kawasaki disease shock syndrome (KDSS) is a rare Kawasaki disease (KD) manifestation.The pediatricians are not aware of the full range of clinical characteristics of KDSS.Objective:We aimed to investigate t...Importance:Kawasaki disease shock syndrome (KDSS) is a rare Kawasaki disease (KD) manifestation.The pediatricians are not aware of the full range of clinical characteristics of KDSS.Objective:We aimed to investigate the clinical features,diagnosis and treatment of KDSS in two patients and we included a literature review.Methods:We collected and analyzed the clinical data for two patients with KDSS.Additionally,using 'Kawasaki diseases shock syndrome' as a key phrase,we searched PubMed,Biotechnology Information and Wanfang Data Knowledge Service Platform databases for any similar reports between January 2009 and March 2017.Results:Both of our patients diagnosed with KD developed sustained hypotension during the course of intravenous immunoglobulin treatment,as well as hypoalbuminemia,and increased C-reactive protein and brain natriuretic peptide levels during hypotension.Both patients responded well to fluid resuscitation and inotropic support.No aneurysms formed in either patient during follow-up.We reviewed two related studies in Chinese and 11 studies in English.Interpretation:KD may present with severe shock,and requires proper diagnosis and rapid treatment.The prognosis for most patients with KDSS is excellent.展开更多
Combining high conductivity,hydrophilicity and excellent electrochemical perfo rmance in one,MXe nes have attracted increasing attention since their inception.However,easy to stack caused by the van der Waals’force b...Combining high conductivity,hydrophilicity and excellent electrochemical perfo rmance in one,MXe nes have attracted increasing attention since their inception.However,easy to stack caused by the van der Waals’force between the layers limits their practical application.Fortunately,intercalating other substances between layers of MXe nes and getting intercalated MXene-based layered composites(IMLCs)with open structure can improve their physical and chemical properties effectively.Larger available surface helps expose more active sites and enlarged layer spacing facilitates ion transport.In addition,other substances fixed in the interlayers by MXenes’two-dimensional confinement effect can produce synergistic effect and expand their applicable range greatly.This review is dedicated to summarizing the preparation methods and applications of IMLCs,emphasizing the advantages of them in the fields of energy storage,catalysis,sensors,electromagnetic interference(EMI)shielding and biomedicine.Furthermore,prospects and further developments in these gratifying fields are also commented.展开更多
文摘Kawasaki disease(KD) is an acute and self-limited febrile disease characterized by fever, polymorphic rash, bulbar conjunctival congestion, redness of the lip mucosa, unilateral cervical lymphadenopathy, erythema, and edema of the extremities. KD was reported first by Tomisaku Kawasaki, a Japanese scholar, in 1967[1]. Since then, the disease has been reported worldwide, with significant differences observed in its incidence in different regions.
文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up.
文摘Importance:Kawasaki disease shock syndrome (KDSS) is a rare Kawasaki disease (KD) manifestation.The pediatricians are not aware of the full range of clinical characteristics of KDSS.Objective:We aimed to investigate the clinical features,diagnosis and treatment of KDSS in two patients and we included a literature review.Methods:We collected and analyzed the clinical data for two patients with KDSS.Additionally,using 'Kawasaki diseases shock syndrome' as a key phrase,we searched PubMed,Biotechnology Information and Wanfang Data Knowledge Service Platform databases for any similar reports between January 2009 and March 2017.Results:Both of our patients diagnosed with KD developed sustained hypotension during the course of intravenous immunoglobulin treatment,as well as hypoalbuminemia,and increased C-reactive protein and brain natriuretic peptide levels during hypotension.Both patients responded well to fluid resuscitation and inotropic support.No aneurysms formed in either patient during follow-up.We reviewed two related studies in Chinese and 11 studies in English.Interpretation:KD may present with severe shock,and requires proper diagnosis and rapid treatment.The prognosis for most patients with KDSS is excellent.
基金supported by the National Natural Science Foundation of China(Nos.21776061,21978069,21707081 and 41807128)the program for Science&Technology Innovation Team in Universities of Henan Province(No.19IRTSTHN029)。
文摘Combining high conductivity,hydrophilicity and excellent electrochemical perfo rmance in one,MXe nes have attracted increasing attention since their inception.However,easy to stack caused by the van der Waals’force between the layers limits their practical application.Fortunately,intercalating other substances between layers of MXe nes and getting intercalated MXene-based layered composites(IMLCs)with open structure can improve their physical and chemical properties effectively.Larger available surface helps expose more active sites and enlarged layer spacing facilitates ion transport.In addition,other substances fixed in the interlayers by MXenes’two-dimensional confinement effect can produce synergistic effect and expand their applicable range greatly.This review is dedicated to summarizing the preparation methods and applications of IMLCs,emphasizing the advantages of them in the fields of energy storage,catalysis,sensors,electromagnetic interference(EMI)shielding and biomedicine.Furthermore,prospects and further developments in these gratifying fields are also commented.
