Effectivity and safety of trifocal intraocular lenses and capsular tension rings implantation for cataract patients with axial high myopia

●AIM:To assess effectivity and safety of trifocal intraocular lenses(IOLs)and capsular tension rings in treating cataract patients with axial high myopia.●METHODS:A prospective nonrandomized controlled clinical trial was conducted.Totally 98 eyes(74 patients)who underwent femtosecond laser-assisted cataract surgery(FLACS)with trifocal IOLs were enrolled in the study and followed up for 2y after surgery:46 eyes(33 patients)with capsular tension ring implantation in the long axial lengths(AL)group(26<AL<29 mm)and 52 eyes(41 patients)in the normal AL group(22<AL<24.5 mm).Postoperative outcomes about effectivity and safety,including the subjective and objective visual quality,and postoperative complications were assessed.●RESULTS:Uncorrected distance visual acuity at 5 m and uncorrected intermediate visual acuity at 60 and 80 cm in the long AL group were significantly worse than those in the normal AL group at 3mo postoperatively(P<0.05).The differences in reading speed,spectacle independence and potential visual complaints between the two groups were not statistically significant(P>0.05).The dysfunctional lens index and total modulation transfer function(MTF)average height were similar between the two groups.The postoperative internal coma aberrations in the axial high myopia eyes were significantly higher than that in the normal AL group(P<0.05).The total satisfaction score in the long AL group(91.32±2.76)was slightly higher than that in the normal AL group(90.36±3.47),but there was no difference(P=0.136).A statistically negative correlation was found between corrected distance visual acuity(CDVA)and dysfunctional lens index(r=-0.382,P=0.009),and between CDVA and the total MTF average height(r=-0.374,P=0.01).But there was no significant correlation between CDVA and total satisfaction score(r=0.059,P=0.696).Postoperative complications mainly presented as posterior capsular opacity(PCO),retinal detachment and cystoid macular edema.There was no difference in the incidence of fundus disease(6.5%vs 3.8%,P=0.663)or PCO(17.4%vs 7.7%,P=0.217)between the two groups at two years.●CONCLUSION:The utilization of trifocal IOL and capsular tension ring implantation is beneficial for cataract patients with axial high myopia undergoing FLACS.This approach not only ensures excellent subjective feelings and objective visual quality,but also does not increase the incidence of postoperative complications.

分离格栅视觉诱发电位与蓝黄视野检查诊断开角型青光眼的性能比较

目的:评估分离格栅视觉诱发电位(IC-VEP)在诊断开角型青光眼中的表现,并将其与蓝黄色视野检查法(B/YP)和光学相干断层扫描(OCT)进行比较。方法:通过回顾性分析,对来自中国的101例受试者(正常组35例;早期青光眼30例,中晚期青光眼患者36例)分别进行IC-VEP、蓝黄色视野检查和OCT等检查。计算IC-VEP、视野检查法和OCT对检测青光眼的敏感度以及这三种方法之间的一致性,以评估其临床表现。结果:早期POAG组的IC-VEP、蓝黄色视野检查和OCT的敏感度分别为70.00%、70.00%、63.33%。在中晚期POAG组中,IC-VEP、OCT和蓝黄色视野检查的敏感度分别为86.11%、88.89%、91.67%。其中IC-VEP的特异性为91.43%。IC-VEP的结果与OCT和蓝黄色视野测试高度一致(kappa:0.721~1.000,P<0.05)。结论:作为视觉功能的客观检查手段,IC-VEP可用于青光眼的早期诊断,也可用于监测可疑青光眼患者的RGC功能。

飞秒激光辅助白内障手术对黄斑形态的影响

目的:观察飞秒激光辅助白内障手术对黄斑形态的影响。方法:回顾性分析。选取2019-06/2020-05行白内障手术患者79例79眼,分为研究组(行飞秒激光辅助超声乳化手术的白内障患者38例38眼)和对照组(行传统超声乳化手术的白内障患者41例41眼)。采用OCT的共焦激光成像技术,收集术前1d,术后1wk,1mo的黄斑小凹厚度和黄斑小凹区、内环区、外环区3个区域平均视网膜厚度,并将术前术后及组间进行比较。结果:研究组和对照组在术后1wk,1mo时,黄斑小凹厚度、小凹区厚度、外环区厚度较术前均无差异(P>0.05);两组手术前后不同时间内环区黄斑厚度有差异(P<0.001)。其中研究组术后1wk内环区黄斑厚度较术前轻度增加,但无差异(P=0.057),术后1mo较术前和术后1wk均明显增加(均P<0.001)。对照组术后1wk,1mo均较术前明显增加(均P<0.001),术后1mo较1wk仍轻度增加(P=0.017)。内环区组间比较:术后1wk内环区黄斑厚度对照组明显高于研究组(t=6.233,P<0.05);术后1mo内环区黄斑厚度仍略高于研究组(t=7.055,P<0.05)。结论:飞秒激光辅助白内障手术无明显增加黄斑损害的风险,相较于传统手术方式早期发生黄斑水肿的概率更低,是一种较为安全的手术选择。

飞秒激光辅助超声乳化联合房角分离术治疗急性闭角型青光眼合并白内障

目的:观察飞秒激光辅助白内障超声乳化联合房角分离术治疗急性闭角型青光眼合并白内障患者的临床疗效。方法:回顾性分析。选取我院2019-03/2021-04期间收治的实施飞秒激光辅助白内障超声乳化联合房角分离术的合并白内障的急性闭角型青光眼患者29例34眼,观察手术前后最佳矫正视力、眼压、房角形态、中央前房深度、角膜内皮细胞计数、中央角膜厚度的变化并分析术后并发症情况。结果:术后最佳矫正视力较术前明显提高,术前与术后1mo最佳矫正视力具有差异(Z=-5.126,P<0.01)。术后1d,1wk,1mo眼压分别为16.72±2.12、13.73±1.68、12.87±3.54mmHg,与术前眼压28.67±4.13mmHg比较有差异(均P<0.01)。房角镜检查术后1mo的房角黏连范围与术前比较明显减少(t=21.32,P<0.01),术后1mo中央前房深度、房角开放距离及小梁虹膜夹角均显著大于术前(t=-3.37、-3.68、-5.61,均P<0.01)。角膜内皮细胞计数、中央角膜厚度与术前比较均无差异(P>0.05)。术中术后均未出现相关严重并发症,术后满意度高。结论:飞秒激光辅助白内障超声乳化联合房角分离术可有效治疗合并白内障的急性闭角型青光眼,同时降低手术风险,提高手术安全性及成功率。