Background:Several studies have investigated the association between smoking and anal abscess and anal fistula (AA/F) diseases.However,the relationship between cigarette smoking and AA/F remains unclear.This study ...Background:Several studies have investigated the association between smoking and anal abscess and anal fistula (AA/F) diseases.However,the relationship between cigarette smoking and AA/F remains unclear.This study sought to assess the role of smoking in anorectal male patients in a Chinese population.Methods:In this retrospective study,a questionnaire,including smoking history,was completed over a 3-month period by male inpatients in the Proctology Department of China-Japan Friendship Hospital."Cases" were patients who had AA/F,and "controls" were patients with other anorectal complaints.Mann-Whitney U-test and Chi-square test were carried out to examine differences in baseline characteristics between groups.Subsequently,multivariate logistic regression was used to explore any related factors.Results:A total of 977 patients aged from 18 to 80 years were included,excluding those diagnosed with inflammatory bowel disease or diabetes mellitus.Out of this total,805 patients (82.4%) completed the entire questionnaire.Among the 805 patients,334 (41.5%) were cases and 471 (58.5%) were controls.Results showed significant differences between cases and controls (x2 =205.2,P < 0.001),with smoking found to be associated with the development of AA/F diseases (odds ratio:12.331,95% confidence interval:8.364-18.179,P < 0.001).Conclusions:This study suggested smoking to be a potential risk factor for the development of AA/F diseases in a Chinese population.Consequently,current smoking patients should be informed of this relationship,and further research should be conducted to explore and investigate this further.展开更多
文摘Background:Several studies have investigated the association between smoking and anal abscess and anal fistula (AA/F) diseases.However,the relationship between cigarette smoking and AA/F remains unclear.This study sought to assess the role of smoking in anorectal male patients in a Chinese population.Methods:In this retrospective study,a questionnaire,including smoking history,was completed over a 3-month period by male inpatients in the Proctology Department of China-Japan Friendship Hospital."Cases" were patients who had AA/F,and "controls" were patients with other anorectal complaints.Mann-Whitney U-test and Chi-square test were carried out to examine differences in baseline characteristics between groups.Subsequently,multivariate logistic regression was used to explore any related factors.Results:A total of 977 patients aged from 18 to 80 years were included,excluding those diagnosed with inflammatory bowel disease or diabetes mellitus.Out of this total,805 patients (82.4%) completed the entire questionnaire.Among the 805 patients,334 (41.5%) were cases and 471 (58.5%) were controls.Results showed significant differences between cases and controls (x2 =205.2,P < 0.001),with smoking found to be associated with the development of AA/F diseases (odds ratio:12.331,95% confidence interval:8.364-18.179,P < 0.001).Conclusions:This study suggested smoking to be a potential risk factor for the development of AA/F diseases in a Chinese population.Consequently,current smoking patients should be informed of this relationship,and further research should be conducted to explore and investigate this further.