Double-Edged Mossy Cells in Temporal Lobe Epilepsy:Evil in the Early Stage Through a BDNF-Dependent Strengthening Dentate Gyrus Circuit

Temporal lobe epilepsy(TLE),one of the most common drug-resistant epilepsies,is characterized by abnormal recurrent excitatory activity originating from the temporal lobe.In the dentate gyrus(DG)of the hippocampus.