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Copper-Catalyzed Asymmetric Formal Hydroaminomethylation of Alkenes with N,O-Acetals to Access Chiral β-Stereogenic Amines: Dual Functions of the Copper Catalyst 被引量:2
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作者 Yang’en You quyet van pham Shaozhong Ge 《CCS Chemistry》 CAS 2019年第4期455-463,共9页
Chiral amines are synthetically versatile intermedi-ates used for the preparation of a wide range of biologically active compounds and drugs.Compared with the well-developed synthesis ofα-stereogenic amines,the estab... Chiral amines are synthetically versatile intermedi-ates used for the preparation of a wide range of biologically active compounds and drugs.Compared with the well-developed synthesis ofα-stereogenic amines,the establishment of enantioselective protocols to accessβ-stereogenic amines are very limited. 展开更多
关键词 ALKENE AMINOMETHYLATION asymmetric catalysis N O-acetal amine copper
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