Objective. To determine whether morbidly obese women have an increased risk of pregnancy complications and adverse perinatal outcome. Methods. In a retrospect ive study, 2472 women with morbid obesity, defined as a bo...Objective. To determine whether morbidly obese women have an increased risk of pregnancy complications and adverse perinatal outcome. Methods. In a retrospect ive study, 2472 women with morbid obesity, defined as a body mass index (BMI) mo re than 40 were compared with normal weight women (BMI 2025). Fisher and Student tests were used for statistical analysis. Results. In the group of morbidly obe se mothers (BMI greater than 40) as compared with the normal weight mothers, the re was an increased risk of the following outcomes: gravidic hypertension (7.7 v s 0.5%; P< 0.05), preeclampsia (11.5 vs 2%; P< 0.05), gestational diabetes (15 .4 vs 1.8%; P< 0.05), cesarean delivery (50 vs 15.4%; P< 0.05), and macrosomia (42.3 vs 10.3%; P< 0.05). However, we noted a lower rate of prematurity in the obese group (0 vs 11%). Even when morbidly obese women with preexisting diabet es and chronic hypertension were excluded from the analysis, significant differe nces in the perinatal outcomes still persisted. Conclusion. Morbid obesity appea rs to be an independent risk factor for perinatal and gestational complications.展开更多
文摘Objective. To determine whether morbidly obese women have an increased risk of pregnancy complications and adverse perinatal outcome. Methods. In a retrospect ive study, 2472 women with morbid obesity, defined as a body mass index (BMI) mo re than 40 were compared with normal weight women (BMI 2025). Fisher and Student tests were used for statistical analysis. Results. In the group of morbidly obe se mothers (BMI greater than 40) as compared with the normal weight mothers, the re was an increased risk of the following outcomes: gravidic hypertension (7.7 v s 0.5%; P< 0.05), preeclampsia (11.5 vs 2%; P< 0.05), gestational diabetes (15 .4 vs 1.8%; P< 0.05), cesarean delivery (50 vs 15.4%; P< 0.05), and macrosomia (42.3 vs 10.3%; P< 0.05). However, we noted a lower rate of prematurity in the obese group (0 vs 11%). Even when morbidly obese women with preexisting diabet es and chronic hypertension were excluded from the analysis, significant differe nces in the perinatal outcomes still persisted. Conclusion. Morbid obesity appea rs to be an independent risk factor for perinatal and gestational complications.
