Emission and performance study emulsi ed orange peel oil biodiesel in an aspirated research engine

This study paves the way on reducing smoke emission and NO_x emissions of research diesel engine by detailing the e ect of water addition in biodiesel. Fuel samples were prepared with di erent concentrations of water in orange peel oil biodiesel(94% waste orange peel oil biodiesel + 4% water + 2% Span 80(WOPOBDE1) and 90% waste orange peel oil biodiesel + 8% water + 2% Span 80(WOPOBDE2). Span 80 was employed as a nonionic surfactant, which emulsifies water in biodiesel. Experimental results revealed that the nitrogen oxides and smoke emission of orange peel oil biodiesel emulsion were reduced by 11%–19% and 3%–21%, respectively, compared to that of neat orange peel oil biodiesel(WOPOBD). In addition, the introduction of orange peel oil–water emulsions in the diesel engine considerably reduced the emissions of unburned hydrocarbons and carbon monoxide. The overall hydrocarbon emission of WOPOBDE2 was 12.2% lower than that of WOPOBD and 16.3% lower than that of diesel. The overall CO emission of WOPOBDE2 was 17% lower than that of base fuel(WOPOBD) and 21.8% lower than that of diesel. Experimental results revealed that modified fuel had higher brake thermal e ciency and lower brake specific fuel consumption than that of base fuel at all engine brake power levels.

Virtual screening of the inhibitors targeting at the viral protein 40 of Ebola virus

Background:The Ebola virus is highly pathogenic and destructive to humans and other primates.The Ebola virus encodes viral protein 40(VP40),which is highly expressed and regulates the assembly and release of viral particles in the host cell.Because VP40 plays a prominent role in the life cycle of the Ebola virus,it is considered as a key target for antiviral treatment.However,there is currently no FDA-approved drug for treating Ebola virus infection,resulting in an urgent need to develop effective antiviral inhibitors that display good safety profiles in a short duration.Methods:This study aimed to screen the effective lead candidate against Ebola infection.First,the lead molecules were filtered based on the docking score.Second,Lipinski rule of five and the other drug likeliness properties are predicted to assess the safety profile of the lead candidates.Finally,molecular dynamics simulations was performed to validate the lead compound.Results:Our results revealed that emodin-8-beta-D-glucoside from the Traditional Chinese Medicine Database(TCMD)represents an active lead candidate that targets the Ebola virus by inhibiting the activity of VP40,and displays good pharmacokinetic properties.Conclusion:This report will considerably assist in the development of the competitive and robust antiviral agents against Ebola infection.

Zika:How safe is India?

Zika virus,which originated from a forest in Uganda,has affected countries in Africa,Latin America and Asia.Most people infected with Zika are asymptomatic and present with clinical manifestations ranging from mild fever to severe neurological disorders.Recent outbreaks in Southeast Asian countries,Centers for Disease Control and Prevention has warned pregnant woman to avoid nonessential traveling to 11 Asian countries.Reports about the sexual transmission route of Zika have pushed the World Health Organization to declare it a‘public health emergency’.Having this current warning status,it has become mandatory to consider where second highly populated country India stands in terms of spreading awareness and taking precautionary measures against the Zika virus infection.Therefore,this paper aims to highlight the importance of Zika in Indian population by considering several indicators such as the population size and ratio,rates of mortality,closely related diseases,government initiatives,and other micro-level factors which are prone to Zika effects.